HIV Lipodystrophy Syndrome

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HIV Infection/Disease

Lipodystrophy Syndrome

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Treatment
ARV/HAART
Hypercholesterolemia
Hyperlipidemia
Hypertriglyceridemia
Insulin Resistance
Quality of Life

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Last Update: January 26, 2015
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General Reports

Books

FULL-TEXT BOOK CHAPTER
Lipodystrophy Syndrome
Behrens B
HIV Medicine-2003 Hoffmann C, Kamps, BS (editors) Amedeo Group 2003
On-Line Book

Journal Papers, Abstracts, and Commentaries

Lipodystrophy syndrome in HIV treatment-multiexperienced patients: implication of resistin.
Arama V, Munteanu DI, Streinu Cercel A, et al
J Endocrinol Invest. 2014 Feb 15.
Abstract

FULL-TEXT ARTICLE
Role of Mitochondria in HIV Infection and Associated Metabolic Disorders: Focus on Nonalcoholic Fatty Liver Disease and Lipodystrophy Syndrome.
Pérez-Matute P, Pérez-Martínez L, Blanco JR, Oteo JA.
Oxid Med Cell Longev. 2013;2013:493413
Paper

How to diagnose a lipodystrophy syndrome.
Vantyghem MC, Balavoine AS, Douillard C, et al
Ann Endocrinol (Paris). 2012 Jun 27
Abstract

Change in Body Compositions in Female Patients with Human Immunodeficiency Virus related
Lipodystrophy Syndrome.
Jin-Peng Y, Wei Y, Tai-Sheng L, et al
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Aug;33(4):421-6.
Abstract

Evolving perspectives on HIV-associated lipodystrophy syndrome: moving from
lipodystrophy to non-infectious HIV co-morbidities.
Guaraldi G, Baraboutis IG.
J Antimicrob Chemother. 2009 Jul 3
Abstract

HIV lipodystrophy syndrome.
Valente AM, Reis AF, Machado DM,
Arq Bras Endocrinol Metabol. 2005 Dec;49(6):871-81.
Abstract

Redefining lipodystrophy syndrome: risks and impact on clinical decision making.
Lichtenstein KA.
J Acquir Immune Defic Syndr. 2005 Aug 1;39(4):395-400.
Abstract

Current perspectives on HIV-associated lipodystrophy syndrome.
Milinkovic A, Martinez E.
J Antimicrob Chemother. 2005 May 19;
Abstract

Agreement Analysis of Variables Involved in Lipodystrophy Syndrome Definition in HIV-
Infected Patients.
Belloso WH, Quiros RE, Ivalo SA, et al.
J Acquir Immune Defic Syndr 2003 Jan 1;32(1):104-11
Abstract

Lipodystrophy Syndrome and Self-Assessment of Well-Being and Physical Appearance in
HIV-Positive Patients.
Oette M, Juretzko P, Kroidl A, et al.
AIDS Patient Care STDS 2002 Sep;16(9):413-7
Abstract

Metabolic basis of HIV-lipodystrophy syndrome.
Sekhar RV, Jahoor F, White AC, et al.
Am J Physiol Endocrinol Metab 2002Aug;283(2):E332-7
Abstract

Risk factors for the HIV-associated lipodystrophy syndrome in a closed cohort of
patients after 3 years of antiretroviral treatment.
Mauss S, Corzillius M, Wolf E, S
HIV Med 2002 Jan;3(1):49-55
Abstract

Syndrome of lipodystrophy, hyperlipidemia, insulin resistance, and diabetes in treated
patients with human immunodeficiency virus infection.
Graber AL.
Endocr Pract 2001 Nov-Dec;7(6):430-7
Abstract

Insulin resistance in the HIV-lipodystrophy syndrome.
Grinspoon S.
Trends Endocrinol Metab 2001Nov 1;12(9):413-9
Abstract

A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV
nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy
syndrome.
Carr A, Miller J, Law M, Cooper DA.
AIDS 2000 Feb 18;14(3):F25-32
Abstract

Treatment

Journal Papers, Abstracts, and Commentaries

The efficacy and safety of insulin-sensitizing drugs in HIV-associated lipodystrophy
syndrome: a meta-analysis of randomized trials.
Sheth SH, Larson RJ.
BMC Infect Dis. 2010 Jun 23;10(1):183
Abstract

Improvement in Highly Active Antiretroviral Therapy-Induced Metabolic Syndrome
by Treatment with Pioglitazone but Not with Fenofibrate: A 2 x 2 Factorial, Randomized,
Double-Blinded, Placebo-Controlled Trial.
Gavrila A, Hsu W, Tsiodras S et al
Clin Infect Dis. 2005 Mar 1;40(5):745-9.
Abstract

ARV/HAART

Journal Papers, Abstracts, and Commentaries

FULL-TEXT ARTICLE
Uridine Metabolism in HIV-1-Infected Patients: Effect of Infection, of Antiretroviral Therapy
and of HIV-1/ART-Associated Lipodystrophy Syndrome.
Domingo P, Torres-Torronteras J, Pomar V, et al
PLoS One. 2010 Nov 15;5(11):e13896.
Paper

Lipodystrophy syndrome associated with antiretroviral therapy in HIV patients:
considerations for psychosocial aspects.
Fernandes AP, Sanches RS, Mill J, et al
Rev Lat Am Enfermagem. 2007 Oct;15(5):1041-1045.
Abstract

Antiretroviral therapy and the lipodystrophy syndrome, part 2: concepts in
aetiopathogenesis.
Nolan D, John M, Mallal S.
Antivir Ther 2001 Sep;6(3):145-60
Abstract

Conference Reports, Abstracts, and Posters

Cumulative nucleoside exposure as a prognostic marker for development of HIV-
associated lipodystrophy syndrome
WF Pewen, BC Calhoun, SA Riddler, et al,
(15IAC)
Abstract

Lipodystrophy syndrome in HIV infected patients taking a NRTI combination, partial
reversion with a one-week on/off treatment, Oxygen assay, results at 48 weeks
G Hittinger, C Poggi, J M Beyssac, et al
(15IAC)
Abstract

Outcomes of switching from PI-containing regimens to PI-sparing regimens due to
lipodystrophy
MP Lee, GWB Ng, RWY Chung, et al
(15IAC)
Abstract

Hypertriglyceridemia

          Journal Papers, Abstracts, and Commentaries

Treatment of hypertriglyceridemia and HIV: fenofibrate-induced changes in the
expression of chemokine genes in circulating leukocytes.
Alonso-Villaverde C, Aragones G, Beltran-Debon R, et al
AIDS Res Ther. 2009 Nov 23;6(1):26
Abstract

Decrease in LDL size in HIV-positive adults before and after lopinavir/ritonavir
-containing regimen: an index of atherogenicity?
Badiou S, Merle De Boever C, et al.
Atherosclerosis 2003 May;168(1):107-13
Abstract

Peripheral Lipodystrophy

Quality of Life

       Journal Papers, Abstracts, and Commentaries

Health related quality of life and lipodystrophy syndrome among HIV-infected patients.
Preau M, Bouhnik AD, Spire B, et al
Encephale. 2006 Oct;32(5 Pt 1):713-9
Abstract

A qualitative study of the psychosocial implications of lipodystrophy syndrome on
HIV positive individuals.
Power R, Tate HL, McGill SM, Taylor C.
Sex Transm Infect 2003 Apr;79(2):137-141
Abstract

Lipodystrophy Syndrome and Self-Assessment of Well-Being and Physical
Appearance in HIV-Positive Patients.
Oette M, Juretzko P, Kroidl A, et al.
AIDS Patient Care STDS 2002 Sep;16(9):413-7
Abstract

           Conference Reports, Abstracts, and Posters

Quality of life and related psychological factors in HIV-infected patients with
Lipodystrophy Syndrome
A Marin, J L Casado, J Moya, et al
(15IAC)
Abstract

Depression as consequence of the lipodystrophy syndrome in HIV-infected patients
A Marin, J L Casado, J Moya, 3et al
(15IAC)
Abstract

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HIV-Associated Lipodystrophy Syndrome