Medical Advocates

Aspergillosis
Main Page
     
New and Noteworthy         

Pediatric     
Adolescent         
General Reports
Risk Factors
Transmission
Case Studies/Literature Reviews
Epidemiology/Incidence
Prevention
Diagnosis/Diagnostics
Clinical Management
Drugs
 
 

OI Main Page Disease Main Page Main New/Noteworthy Home Page 

Last Update:  June 16, 2008
 Documents identified with this icon are in Portable Document Format (PDF) and require the Adobe Acrobat Reader
New and Noteworthy
     

June 2008
 

 

May 2008
 

General Reports
       

     Journal Papers, Abstracts, and Commentaries  

 
Chemosensitization prevents tolerance of Aspergillus fumigatus to antimycotic drugs.
Kim J, Campbell B, Mahoney N,et al

Biochem Biophys Res Commun. 2008 May 15.
Abstract
 
Strong correlation between serum aspergillus galactomannan index and outcome of |
aspergillosis in patients with hematological cancer: clinical and research implications.
Miceli MH, Grazziutti ML, Woods G, et al 
Clin Infect Dis. 2008 May 1;46(9):1412-22.
Abstract
 
Comparison of the use of administrative data and an active system for surveillance of
invasive aspergillosis .
Chang DC, Burwell LA, Lyon GM, et al
Infect Control Hosp Epidemiol. 2008 Jan;29(1):25-30
Abstract
 
Role of macrophages in host defense against aspergillosis and strategies for immune
augmentation.
Segal BH.  

Oncologist.
2007;12 Suppl 2:7-13.
Abstract
 
Aspergillosis and sarcoidosis.
Lachkar S, Dominique S, Thiberville L, et al  

Rev Mal Respir.
2007 Oct;24(8):943-53.
Abstract
 
Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of
invasive aspergillosis.

Ibrahim-Granet O, Dubourdeau M
Cell Microbiol. 2007 Aug 17
Abstract
 
Using rare diseases as models for biobehavioral research: allergic bronchopulmonary
aspergillosis.

Greenberger PA, Yucha CB, Janson S, Huss K.
et al
Allergy Asthma Proc. 2007 Jul-Aug;28(4):489-96
Abstract
 
Immune reconstitution inflammatory syndrome in cancer patients with pulmonary aspergillosis
recovering from neutropenia: Proof of principle, description, and clinical and research implications.

Miceli MH, Maertens J, Buvé K, et al
Cancer. 2007 Jul 1;110(1):112-20.
Abstract
 
Isolation of Aspergillus in critically ill patients: a potential marker of poor outcome.
Khasawneh F, Mohamad T, Moughrabieh MK, et al 

J Crit Care.
2006 Dec;21(4):322-7.
Abstract
 
Post-operative aspergillosis.
Pasqualotto AC, Denning DW.

Clin Microbiol Infect.
2
006 Nov;12(11):1060-76.
Abstract
 
Comparison of epidemiological, clinical, and biological features of invasive aspergillosis
in neutropenic and nonneutropenic patients: a 6-year survey.
Cornillet A, Camus C, Nimubona S, et al 

Clin Infect Dis.
2006 Sep 1;43(5):577-84.
Abstract
 
Late-onset invasive aspergillosis in organ transplant recipients in the current era.
Singh N, Limaye AP, Forrest G, et al;

Med Mycol. 2006 Aug;44(5):445-9
Abstract
 
Invasive aspergillosis with central nervous system dissemination in a presumably
immunocompetent, non-neutropenic patient: case report and review.

Garcia RJ, Troya P, Edwards C.

South Med J. 2006 Jun;99(6):607-10.
Abstract
 
Systemic fungal infections caused by Aspergillus species: epidemiology, infection
process and virulence determinants.
Brakhage AA

Curr Drug Targets.
2005 Dec;6(8):875-86.
Abstract
 
Rapidly advancing invasive endomyocardial aspergillosis.
Davutoglu V, Soydinc S, Aydin A, Karakok M.  

Am Soc Echocardiogr.
2005 Feb;18(2):185-187.
Abstract

Invasive aspergillosis in patients with solid tumors.
Ohmagari N, Raad II, Hachem R, Kontoyiannis DP. 

Cancer. 2004 Sep 27
Abstract
 
Localised invasive sino-orbital aspergillosis: characteristic features.
Sivak-Callcott JA, Livesley N, et al
Br J Ophthalmol. 2004 May;88(5):681-687.
Abstract
 
Invasive aspergillosis in critically ill patients: attributable mortality and excesses in length
of ICU stay and ventilator dependence.
Vandewoude KH, Blot SI, Benoit D ,et al
J Hosp Infect. 2004 Apr;56(4):269-76.
Abstract

Invasive aspergillosis in patients with hematologic malignancies.
Wiederhold NP, Lewis RE, Kontoyiannis DP
.  
Pharmacotherapy.
2003 Dec; 23(12): 1592-610.
Abstract
 
Aspergillosis caused by non-fumigatus Aspergillus species: risk factors and in vitro
susceptibility compared with Aspergillus fumigatus.

Torres HA, Rivero GA, Lewis RE et al.  
Diagn Microbiol Infect Dis
2003 May;46(1):25-8
Abstract
 
Clinical applicability of the new EORTC/MSG classification for invasive pulmonary
aspergillosis in patients with hematological malignancies and autopsy-confirmed
invasive aspergillosis.
Subira M, Martino R, Rovira M, et al.
 
Ann Hematol
2003 Feb;82(2):80-2
Abstract
 
Invasive aspergillosis in 2002: an update.
Kontoyiannis DP, Bodey GP. 
Eur J Clin Microbiol Infect Dis 2002 Mar;21(3):161-72
Abstract   
 
Aspergillosis among people infected with human immunodeficiency virus: incidence and
survival. Adult and Adolescent Spectrum of HIV Disease Project.
Holding KJ, Dworkin MS, Wan PC, et al.

Clin Infect Dis
2000 Nov;31(5):1253-7\
Abstract
 

Risk Factors
       

           Journal Papers, Abstracts, and Commentaries

 
Higher risk of cytomegalovirus and aspergillus infections in recipients of T cell-depleted
unrelated bone marrow: analysis of infectious complications in patients treated with T cell

depletion versus immunosuppressive therapy to prevent graft-versus-host disease.
van Burik JA, Carter SL, Freifeld AG, et al. 
Biol Blood Marrow Transplant. 2007 Dec;13(12):1487-98
Abstract
 
Non-decompensated cirrhosis as a risk factor for invasive aspergillosis: a case report and
review of the immune dysfunction of cirrhosis.

Lipke AB, Mihas AA.

Am J Med Sci.
2007 Oct;334(4):314-6

Abstract
 
Occupational risk assessment of aspergillosis after renal transplantation.
Praz-Christinaz SM, Lazor-Blanchet C, Binet I,et al
Transpl Infect Dis. 2007 May 19;
Abstract
 
Aspergillosis related to long-term nasal corticosteroid use.
Bratton RL, Brazis PW, Hellinger WC, et al.
Mayo Clin Proc 2002 Dec;77(12):1353-7
Abstract
 

Transmission
       

Nosocomial

           Journal Papers, Abstracts, and Commentaries

 
Nosocomial aspergillosis in outbreak settings.
R-P Vonberg, Gastmeier P.

J Hosp Infect.
2006 May 16;
Abstract
 

Prevention
       

        Journal Papers, Abstracts, and Commentaries  

 
Reduction of invasive aspergillosis incidence among immunocompromised patients after
control of environmental exposure.
Bénet T, Nicolle MC, Thiebaut A, et al 

Clin Infect Dis.
2007 Sep 15;45(6):682-6.
Abstract
 
Safety of aerosolized liposomal versus deoxycholate amphotericin B formulations for
prevention of invasive fungal infections following lung transplantation: a retrospective
study.
Lowry CM, Marty FM, Vargas SO, et al
Transpl Infect Dis. 2007 Jun;9(2):121-5.
Abstract
 
Comparison of DNA extraction methods for Aspergillus fumigatus using real-time PCR.
Griffiths LJ, Anyim M, Doffman SR, et al  

J Med Microbiol.
2006 Sep;55(Pt 9):1187-91.
Abstract
 
Detection of Aspergillus DNA in cerebrospinal fluid by a nested PCR assay in patients with
 cerebral aspergillosis.
Hummel M, Spiess B, Kentouche K, et al 
J Clin Microbiol. 2006 Aug
 30;
Abstract
 
Efficacy of environmental measures to decrease the risk of hospital-acquired
aspergillosis in patients hospitalised in haematology wards.
Berthelot P, Loulergue P, Raberin H, et al

Clin Microbiol Infect. 2006 Aug;12(8):738-44.
Abstract

Prophylactic administration of liposomal amphotericin B is superior to treatment in a murine
model of invasive aspergillosis after hematopoietic cell transplantation.

BitMansour A, Brown JM

Infect Dis 2002 Jul 1;186(1):134-7
Abstract

FULL-TEXT ARTICLE
Guidelines for Preventing Opportunistic Infections Among HIV-Infected Persons --
2002: Recommendations of the U.S. Public Health Service and the Infectious
Diseases Society of America
MMWR June 14, 2002 / Vol. 51 / No. RR--8   
Paper

 

Diagnosis/Diagnostics General
       

          Journal Papers, Abstracts, and Commentaries

 
FULL TEXT PDF ARTICLE
Development and optimization of quantitative PCR for the diagnosis of invasive aspergillosis with bronchoalveolar
lavage fluid.

Khot PD, Ko DL, Hackman RC, Fredricks DN.
BMC Infect Dis. 2008 May 29;8(1):73.
Paper
 
Utility of a microsatellite assay for identifying clonally related outbreak isolates of
Aspergillus fumigatus.

Balajee SA, de Valk HA, Lasker BA, et al
J Microbiol Methods. 2008 Feb 23
Abstract
 
An Aspergillus Myocardial Abscess Diagnosed by Echocardiography.
Kemdem A, Ahmad I, Ysebrand L, et al
 
J Am Soc Echocardiogr.
2008 Jan 25
Abstract
 
Aspergillus galactomannan testing in patients with long-term neutropenia: implications for
clinical management.

Penack O, Rempf P, Graf B, Blau IW, Thiel E.
Ann Oncol. 2008 Jan 27
Abstract
 
Invasive pulmonary aspergillosis - imaging and invasive potential of diagnosis.
Haber J, Cervenková J.
Klin Mikrobiol Infekc Lek. 2007 Oct;13(5):191-195
Abstract
 
Detection of invasive aspergillosis by PCR and real-time PCR - benefits and drawbacks.
Lengerová M, Ráčil Z, Hrnčířová K, et al
Klin Mikrobiol Infekc Lek. 2007 Oct;13(5):184-190.
Abstract
 
Contribution of galactomannan antigen detection to early diagnosis of invasive aspergillosis.
Ráčil Z, Kocmanová I, Wagnerová B, et al
Klin Mikrobiol Infekc Lek. 2007 Oct;13(5):176-183.
Abstract
 
Differentiating Intracranial Aspergillosis from a High Grade Glioma Using MRI and MR
Spectroscopic Imaging.
Pollack E, Bhaya A, Law M.

J Neuroimaging.
2007 Oct;17(4):361-6.
Abstract
 
Aspergillus vertebral osteomyelitis in chronic leukocyte leukemia patient diagnosed by a novel
panfungal polymerase chain reaction method.

Dayan L, Sprecher H, Hananni A, et al
 
Spine
J. 2007 Sep-Oct;7(5):615-7.
Abstract
 
Comparison of serum markers for allergic bronchopulmonary aspergillosis in cystic
fibrosis.
Latzin P, Hartl D, Regamey N, et al
Eur Respir J. 2007 Sep 26;
Abstract
 
The Pan-AC assay: a single-reaction real-time PCR test for quantitative detection of a
broad range of Aspergillus and Candida species.

Basková L, Landlinger C, Preuner S, Lion T. 
J Med Microbiol. 2007 Sep;56(Pt 9):1167-73
Abstract
 
Comparison of the Real-time Nucleic Acid Sequence-based Amplification (RTi-NASBA)
with Conventional NASBA, and Galactomannan Assay for the Diagnosis of Invasive
Aspergillosis.
Yoo JH, Choi SM, Lee DG, et al 
J Korean Med Sci. 2007 Aug;22(4):672-6.
Abstract
 
Allergic bronchopulmonary aspergillosis' diagnosis remains a challenge.
de Oliveira E, Giavina-Bianchi P, et al  
Respir Med. 2007 Aug 2;
Abstract
 
A comparison of galactomannan-ELISA and a newly developed galactomannan-LATEX test in the
serologic diagnosis of invasive aspergillosis in patients with hematologic malignancies.

Keutgen X, Hachem R, Jiang Y, et al 

Eur J Clin Microbiol Infect Dis
. 2007 Jul 11;
Abstract
 
Prospective Aspergillus Galactomannan Antigen Testing in Pediatric Hematopoietic Stem Cell
Transplant Recipients.

Steinbach WJ, Addison RM, McLaughlin L, et al  

Pediatr Infect Dis J.
2007 Jul;26(7):558-564.
Abstract
 
Bronchoalveolar lavage (BAL) galactomannan in the diagnosis of pulmonary aspergillosis among
non-immunocompromised hosts.

Nguyen MH, Jaber R, Leather HL, et al
J Clin Microbiol. 2007 Jun 27;
Abstract
 
FULL TEXT PDF ARTICLE
A systematic literature review on the diagnosis of invasive aspergillosis using polymerase chain
reaction (PCR) from bronchoalveolar lavage clinical samples.

Tuon FF.
Rev Iberoam Micol. 2007 Jun;24(2):89-94.
Paper
 
Comparison of CT features of Aspergillus and bacterial pneumonia in severely neutropenic
patients.

Bruno C, Minniti S, Vassanelli A, Pozzi-Mucelli R.
J Thorac Imaging. 2007 May;22(2):160-5.
Abstract
 
Optimization of the cutoff value for the Aspergillus double-sandwich enzyme immunoassay.
Maertens JA, Klont R, Masson C, et al
Clin Infect Dis. 2007 May 15;44(10):1329-36.
Abstract
 
FULL TEXT PDF ARTICLE
A systematic literature review on the diagnosis of invasive aspergillosis using polymerase
chain reaction (PCR) from bronchoalveolar lavage clinical samples.

Tuon FF.

Rev Iberoam Micol.
2007 Jun;24(2):89-94.

Paper
 
Relevant imaging findings of cerebral aspergillosis on MRI: a retrospective case-based study in
immunocompromised patients.

Gabelmann A, Klein S, Kern W, et al
Eur J Neurol. 2007 May;14(5):548-55.
Abstract
 
Aspergillus galactomannan antigen in the bronchoalveolar lavage fluid for the diagnosis of
invasive aspergillosis in lung transplant recipients.

Husain S, Paterson DL, Studer SM, et al
Transplantation. 2007 May 27;83(10):1330-6
Abstract
 
Update on the contribution of galactomannan for the diagnosis of invasive aspergillosis.
Aquino VR, Goldani LZ, Pasqualotto AC. 
Mycopathologia. 2007 Apr;163(4):191-202.
Abstract
 
Bronchoalveolar lavage galactomannan in the diagnosis of invasive pulmonary aspergillosis
among solid organ transplant recipients.

Clancy CJ, Jaber RA, Leather HL, et al

J Clin Microbiol.
2007 Apr 11
Abstract
 
Potential role of the cellular allergen stimulation test (CAST) in diagnosis of allergic
bronchopulmonary aspergillosis (ABPA) in cystic fibrosis.

Ringer S, Hipler UC, Elsner P, et al  
Pediatr Pulmonol. 2007 Apr;42(4):314-8.
Abstract
 
Comparison of Two Highly Discriminatory Molecular Fingerprinting Assays for Analysis of
Multiple Aspergillus fumigatus Isolates from Patients with Invasive Aspergillosis.

de Valk HA, Meis JF, de Pauw BE, et al
 
J Clin Microbiol.
2007 Mar 21
Abstract
 
Galactomannan Antigen Enzyme-Linked Immunosorbent Assay for Diagnosis of Invasive
Aspergillosis after Hematopoietic Stem Cell Transplantation.
Foy PC, van Burik JA, Weisdorf DJ.
Biol Blood Marrow Transplant. 2007 Feb 1
Abstract
 
Imaging findings in acute invasive pulmonary aspergillosis: clinical significance of the halo
sign.
Greene RE, Schlamm HT, Oestmann JW, et al 
Clin Infect Dis. 2007 Feb 1;44(3):373-9.
Abstract
 
Galactomannan antigen detection in the diagnosis of invasive aspergillosis.
Verdaguer V, Walsh TJ, Hope W, Cortez KJ. 

Expert Rev Mol Diagn.
2007 Jan;7(1):21-32.
Abstract
 
Two non-invasive diagnostic tools for invasive aspergilosis: (1-3)-beta-D-glucan and the
galactomannan assay.

Kelaher A.
Clin Lab Sci. 2006 Fall;19(4):222-4.
Abstract

Usefulness of the MSG/IFICG/EORTC diagnostic criteria of invasive pulmonary aspergillosis
in the clinical management of patients with acute leukaemia develping pulmonary infiltrates.
Borlenghi E, Cattaneo C, Capucci MA, et al 
Ann Hematol. 2006 Nov 21
Abstract
 

Diagnosis of aspergilloma in a pleural cavity (persistent pneumothorax) using classic
imaging methods.
Kreymborg KG, Seyfarth HJ, Gessner C, et al  
 
Mycoses.
2006 May;49(3):210-5.
Abstract
 
Diagnosis of invasive aspergillosis using a galactomannan assay: a meta-analysis.
Pfeiffer CD, Fine JP, Safdar N. 

Clin Infect Dis. 2006 May 15;42(10):1417-727.
Abstract
 
Diagnosis of aspergilloma in a pleural cavity (persistent pneumothorax) using classic
imaging methods.
Kreymborg KG, Seyfarth HJ, Gessner C, et al 
Mycoses. 2006 May;49(3):210-5.
Abstract
 
Assessment of a commercial sandwich ELISA in the diagnosis of aspergillosis in falcons.
Arca-Ruibal B, Wernery U, Zachariah R, et al    

Vet Rec
. 2006 Apr 1;158(13):442-4.
Abstract
 
Multidimensional volumetric imaging of pulmonary infiltrates for measuring therapeutic response
to antifungal therapy in experimental invasive pulmonary aspergillosis.
Petraitis V, Petraitiene R, Solomon J, et al   
Antimicrob Agents Chemother. 2006 Apr;50(4):1510-7.
Abstract
 
Recombinant antigens as diagnostic markers for aspergillosis.
Sarfati J, Monod M, Recco P, et al
Diagn Microbiol Infect Dis. 2006 Apr 18;
Abstract
 
Prospective Evaluation of a Polymerase Chain Reaction-ELISA Targeted to Aspergillus
fumigatus and Aspergillus flavus for the Early Diagnosis of Invasive Aspergillosis in
Patients with Hematological Malignancies.
Florent M, Katsahian S, Vekhoff A, et al

J Infect Dis. 2006 Mar 1;193(5):741-7.
Abstract
 
Cavitating invasive pulmonary aspergillosis visualized and diagnosed by ultrathin
bronchoscopy.
Oki M, Saka H, Sako C, Tanaka S, et al
Chest. 2006 Feb;129(2):475-9.
Abstract
 
Diagnosis of invasive aspergillosis and mucormycosis in immunocompromised patients by
seminested PCR assay of tissue samples.

Rickerts V, Just-Nubling G, Konrad F, et al
Eur J Clin Microbiol Infect Dis. 2006 Jan;25(1):8-13.
Abstract
 
A WEEK-IN-REVIEW FEATURED REPORT
Current Approaches to Diagnosis and Treatment of Invasive Aspergillosis.
Segal BH, Walsh TJ.   
Am J Respir Crit Care Med. 2005 Dec 30;

Abstract
 
Evaluation of the role of real-time PCR in the diagnosis of invasive aspergillosis.
Ferns RB. 
Leuk Lymphoma. 2006 Jan;47(1):15-20. et al
Abstract
 
Initial CT manifestations of invasive pulmonary aspergillosis in 45 non-HIV
immunocompromised patients: association with patient outcome?
Horger M, Hebart H, Einsele H, et a
l
Eur J Radiol. 2005 Sep;55(3):437-44
Abstract
 
The contribution of galactomannan detection in the diagnosis of invasive aspergillosis
in bone marrow transplant recipients.
Pereira CN, Del Nero G, Lacaz CS, Machado CM.

Mycopathologia.
2005 Jun;159(4):487-93.
Abstract
 
Chest computed tomography of late invasive aspergillosis after allogeneic hematopoietic
stem cell transplantation.
Kojima R, Tateishi U, Kami M, et al 
 
Biol Blood Marrow Transplant.
2005 Jul;11(7):506-11.
Abstract
 
Direct detection of angioinvasive pulmonary aspergillosis in immunosuppressed patients:
preliminary results with high-resolution 16-MDCT angiography.
Sonnet S, Buitrago-Tellez CH, Tamm M, et al 

AJR Am J Roentgenol.
2005 Mar;184(3):746-51
Abstract
 
Monochrome LightCycler PCR assay for detection and quantification of five common
 species of Candida and Aspergillus.
Bu R, Sathiapalan RK, Ibrahim MM, Al-Mohsen   

J Med Microbiol.
2005 Mar;54(Pt 3):243-8.
Abstract
 
Diagnosis of IPA in HIV: the role of the chest X-ray and radiologist.
Zaspel U, Denning DW, Lemke AJ, et al  
Eur Radiol. 2004 Nov;14(11):2030-7.
Abstract
 
Diagnosing invasive aspergillosis during antifungal therapy by PCR analysis of blood
samples.
Lass-Florl C, Gunsilius E, Gastl G, et al 
J Clin Microbiol. 2004 Sep;42(9):4154-7
Abstract
 
Diagnosis of IPA in HIV: the role of the chest X-ray and radiologist.
Zaspel U, Denning DW, Lemke AJ, et al 
Eur Radiol. 2004 Aug 11
Abstract
 
Prospective Assessment of Platelia  Aspergillus Galactomannan Antigen for the
Diagnosis of Invasive Aspergillosis in Lung Transplant Recipients.
Husain S, Kwak EJ, Obman A ,et al
Am J Tra Am J Transplant. 2004 May;4(5):796-802
Abstract
 

Detection of Circulating Aspergillus fumigatus Galactomannan: Value and Limits of the
Platelia Test for Diagnosing Invasive Aspergillosis.
Pinel C, Fricker-Hidalgo H, Lebeau B, et al
J Clin Microbiol 2003 May;41(5):2184-6
Abstract
 
Value of antigen detection using an enzyme immunoassay in the diagnosis and
prediction of invasive aspergillosis in two adult and pediatric hematology units during a
4-year prospective study.
Sulahian A, Boutboul F, Ribaud P, et al.

Cancer 2001 Jan 15;91(2):311-8
Abstract
 
In vitro susceptibility testing methods for caspofungin against Aspergillus and Fusarium
isolates.

Arikan S, Lozano-Chiu M, Paetznick V, Rex JH.

Antimicrob Agents Chemother
2001 Jan;45(1):327-30
Abstract
 
Lack of correlation of in vitro amphotericin B susceptibility testing with outcome in a
murine model of Aspergillus infection.
Johnson EM, Oakley KL, Radford SA, et al.
J Antimicrob Chemother 2000 Jan;45(1):85-93
Abstract
 
Polymerase chain reaction detection of aspergillus DNA in experimental models
of invasive aspergillosis.
Loeffler J, Kloepfer K Hebart H, et al.
J Infect Dis 2002 Apr 15;185(8):1203-6
Abstract


OI Main Page Disease Main Page Main New/Noteworthy Home Page 

Aspergillosis Main Page