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 Guidelines



 
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Last Update: August 23, 2008
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General Reports
 
Internet Citations
 
  FULL-TEXT PDF DOCUMENT
 Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection
 HIV-Infected Children convened by the National Resource Center at the François-
Xavier Bagnoud Center, UMDNJ, The Health Resources and Services Administration
(HRSA), and The National Institutes of Health (NIH)
Updated February 28, 2008
 PDF Guidelines
 
      Journal Papers, Abstracts, and Commentaries
 
 
Analyses of HIV-1 Drug-Resistance Profiles Among Infected Adolescents Experiencing Delayed Antiretroviral
Treatment Switch After Initial Nonsuppressive Highly Active Antiretroviral Therapy.
Agwu A, Lindsey JC, Ferguson K, et al
AIDS Patient Care STDS. 2008 May 15.
 Abstract
 
Long-Term Effects of Highly Active Antiretroviral Therapy on CD4(+) Cell Evolution among
Children and Adolescents Infected with HIV: 5 Years and Counting.
Patel K, Hernán MA, Williams PL, et al
Clin Infect Dis. 2008 Apr 2
 Abstract
 
Virologic Response Using Directly Observed Therapy in Adolescents With HIV: An Adherence Tool.
Purdy JB, Freeman AF, Martin SC, et al
J Assoc Nurses AIDS Care. 2008 Mar-Apr;19(2):158-65.
 Abstract
 
Clinical Outcomes After an Unstructured Treatment Interruption in Children and Adolescents
With Perinatally Acquired HIV Infection.
Saitoh A, Foca M, Viani RM, et al  
Pediatrics. 2008 Mar;121(3):e513-21.
 Abstract
 
FULL TEXT ARTICLE
Impact of highly active antiretroviral therapy (HAART) on the incidence of opportunistic
infections, hospitalizations and mortality among children and adolescents living with HIV/AIDS
in Belo Horizonte, Minas Gerais State, Brazil.
Candiani TM, Pinto J, Cardoso CA, Carvalho IR, et al
Cad Saude Publica. 2007;23 Suppl 3:S414-23.
 Paper
 
Long-Term Observation of Adolescents Initiating HAART Therapy: Three-Year Follow-Up.
Flynn PM, Rudy BJ, Lindsey JC, et al
AIDS Res Hum Retroviruses. 2007 Oct;23(10):1208-1214.
 Abstract
 
Long-term Follow-up of 414 HIV-Infected Romanian Children and Adolescents Receiving
Lopinavir/Ritonavir-Containing Highly Active Antiretroviral Therapy.
Kline MW, Rugina S, Ilie M, et al 
Pediatrics. 2007 Apr 9;
Abstract

FULL TEXT ARTICLE
Retroviral rebound syndrome after treatment discontinuation in a 15 year old girl with
HIV attracted through mother-to-child transmission: case report.
Friman V, Gisslen M.
AIDS Res Ther. 2007 Feb 23;4:
Paper
 
       Conference Reports, Abstracts, and Posters
 
 
n

Outcomes of HAART in a cohort of adolescents in Argentina
 Coll Cardenas P , Fink V,  Balinotti S.
 (4th IAS Conference)
 Abstract
 
The PACTG 1020A Protocol: Atazanavir with or without Ritonavir in HIV-infected Infants,
Children, and Adolescents
 R Rutstein, P Samson, J Kiser, et al
 (14 CROI)
 Abstract
 
Sustained Increased Thymic Output and Decreased Immune Activation in Children and
Adolescents with High Post-therapy Viral Loads while Receiving PI-containing ART
C Rodriguez, L Yin, M Morrow, et al
 (14 CROI)
 Abstract
 
Adiponectin, Leptin, and Antiretroviral Use in HIV-infected Children and Adolescents
MR Araneta, T Ciaraldi, R Henry,  S Spector
 (14 CROI)
 Abstract
 
PDF CONFERENCE POSTER
 Long-term Follow-up of 414 HIV-infected Romanian Children and Adolescents Receiving
Lopinavir/Ritonavir-containing HAART
 M Kline, S Rugina, M Ilie, et al
 (14 CROI)
 PDF Poster  Abstract

HAART in children and adolescents in Latin America: relationship between viral load and
clinical characteristics from the national institute of child health and human development
international site development initiative (NISDI) pediatric study
Oliveira R., Byrne J., Souza R., et al
 (XVI International AIDS Conference)
 Abstract

  
Atazanavir
 
      Journal Papers, Abstracts, and Commentaries
 
 
Pharmacokinetics of Antiretroviral Regimens Containing Tenofovir Disoproxil Fumarate and
Atazanavir/Ritonavir in Adolescents and Young Adults with HIV Infection – Study ATN056.
 Kiser JJ, Fletcher CV, Flynn PM, et al 
Antimicrob Agents Chemother. 2007 Nov 19;
Abstract
Combivir
 
      Journal Papers, Abstracts, and Commentaries
 
 
Intracellular pharmacokinetics of once versus twice daily zidovudine and lamivudine in
adolescents.
 Flynn PM, Rodman J, Lindsey JC, et al 
Antimicrob Agents Chemother. 2007 Oct;51(10):3516-22.
 Abstract

Intracellular Pharmacokinetics of Once vs. Twice Daily Zidovudine and Lamivudine in
Adolescents.
Flynn PM, Rodman J, Lindsey JC, et al 
Antimicrob Agents Chemother. 2007 Jul 30;
 Abstract
Darunavir
 
       Conference Reports, Abstracts, and Posters
 
  Safety and Efficacy of Darunavir Co-administered with Low-dose Ritonavir in Treatment-experienced
Children and Adolescents at Week 24
 R Bologna, S Rugina, P Cahn, et al
 Abstract
Lopinavir
 
      Journal Papers, Abstracts, and Commentaries
 
  A WEEK IN REVIEW FEATURED REPORT
Pharmacokinetics of High-Dose Lopinavir/Ritonavir with and without Saquinavir or Non-Nucleoside
Reverse Transcriptase Inhibitors in HIV Infected Pediatric and Adolescent Patients Previously Treated
with Protease Inhibitors – Study PACTG P1038.
 Robbins BL, Capparelli EV, Chadwick EG, et al
Antimicrob Agents Chemother. 2008 Jul 14.
 Abstract
Tenofovir
 
      Journal Papers, Abstracts, and Commentaries
 
 
Decreased bone mineral density with off-label use of tenofovir in children and adolescents
infected with human immunodeficiency virus.
Purdy JB, Gafni RI, Reynolds JC
J Pediatr. 2008 Apr;152(4):582-4.
  Abstract

Increased beta-2 Microglobulinuria in HIV-1-Infected Children and Adolescents Treated with
Tenofovir
Papaleo A, Warszawski J, Salomon R, et al
Pediatr Infect Dis J. 2007 Oct;26(10):949-951.
 Abstract
Tipranavir
 
       Conference Reports, Abstracts, and Posters
 
 
POSTER
 Efficacy and safety profile of APTIVUS oral solution or capsules co-administered with low dose ritonavir
(APTIVUS/r) in treatment experienced children and teenagers after two years of treatment (Phase I/IIa study)
JC Salazar, P Cahn, C Giaquinto, et al
(XVII Int. AIDS Conference )
 PDF Poster

NEWS RELEASE
New data shows HIV therapy tipranavir (Aptivus) is effective and well tolerated in children
 Boehringer Ingelheim
August 04 2008
 News
Adherence
 
      Journal Papers, Abstracts, and Commentaries
 
 
Patient, Caregiver and Regimen Characteristics Associated With Adherence to Highly Active
Antiretroviral Therapy Among HIV-Infected Children and Adolescents.
Martin S, Elliott-Desorbo DK, Wolters PL 
Pediatr Infect Dis J. 2007 Jan;26(1):61-67.
 Abstract

Predictors of adherence to antiretroviral medications in children and adolescents with HIV
infection.
Williams PL, Storm D, Montepiedra G, et al  |
Pediatrics. 2006 Dec;118(6):e1745-57.
Abstract
 
       Conference Reports, Abstracts, and Posters
 
 
An adolescent peer support group improves adherence to antiretroviral therapy and reduces self
stigma among HIV infected adolescents at joint clinical research centre (JCRC), Kampala
 Musiime V, Kizito H, Ssali F,  et al
 (4th IAS Conference)
 Abstract
 
Compliance of HIV infected adolescents
 Arbune M , Barbuta M , Saveanu L , Tabacaru G
(4th IAS Conference)
 Abstract

Antiretroviral adherence among adolescents in a reference center in
Rio de Janeiro, Brazil
Barreto Filho L.F., Nogueira S., Machado E., et al
 (XVI International AIDS Conference)
 Abstract

  
HAART Adverse Events
 
Central Nervous System
 
       Conference Reports, Abstracts, and Posters
 
  POWERPOINT POSTER PRESENTATION
Impact of highly active antiretroviral therapy on the incidence of HIV-encephalopathy among
perinatally-infected children and adolescents
K Patel
 (XVII International AIDS Confe
rence)
 Poster Presentation
 
Immune Reconstitution Inflammatory Syndrome
 
      Journal Papers, Abstracts, and Commentaries
 
  Immune Reconstitution Inflammatory Syndrome Associated With Progressive Multifocal
Leukoencephalopathy in a Perinatally Acquired Human Immunodeficiency Virus-Infected
Young Adult
Chong TW, Dieudonne A.
Pediatr Infect Dis J. 2007 Nov;26(11):1068-1070.
Abstract

Cutaneous

      Journal Papers, Abstracts, and Commentaries

  Cutaneous EBV-related lymphoproliferative disorder in a 15-year-old boy
with AIDS: an unusual clinical presentation.
Fardet L, Blanche S, Brousse N, et al.
J Pediatr Hematol Oncol 2002 Nov;24(8):666-9
 Abstract
 		  

Endocrine

Cushing’s Syndrome

      Journal Papers, Abstracts, and Commentaries

 
Cushing Syndrome and Severe Adrenal Suppression Caused by Fluticasone and
Protease Inhibitor Combination in an HIV-Infected Adolescent.
St Germain RM, Yigit S, Wells L, et al 
AIDS Patient Care STDS. 2007 Jun;21(6):373-7.
Abstract

Ritonavir-Fluticasone Interaction Causing Cushing Syndrome in HIV-Infected Children
and Adolescents.
 Arrington-Sanders R, Hutton N, Siberry GK.
Pediatr Infect Dis J. 2006 Nov;25(11):1044-1048.
Abstract
 
Hepatic
 
      Journal Papers, Abstracts, and Commentaries
 
  Hepatotoxicity in HIV-infected children and adolescents on antiretroviral therapy.
Gil AC, Lorenzetti R, Mendes GB, et al
Sao Paulo Med J. 2007 Jul;125(4):205-209.
 Abstract
 
Metabolic

      Journal Papers, Abstracts, and Commentaries

 
Evaluation of insulin resistance in a cohort of HIV-infected youth.
Rosso R, Parodi A, d’Annunzio G, Ginocchio F, et al  
Eur J Endocrinol. 2007 Nov;157(5):655-9.
 Abstract

Hyperinsulinemia induced by highly active antiretroviral therapy in an adolescent with
polycystic ovary syndrome who was infected with human immunodeficiency virus.
Vigano A, Manzoni P, Riva S,  et al.   
Fertil Steril 2003 Feb;79(2):422-3
 Abstract

Musculoskeletal

      Journal Papers, Abstracts, and Commentaries

  Bone measures in HIV-1 infected children and adolescents: disparity between quantitative
computed tomography and dual-energy X-ray absorptiometry measurements.
Pitukcheewanont P, Safani D, Church J, Gilsanz V.
Osteoporos Int. 2005 Feb 9;
Abstract

       Conference Reports, Abstracts, and Posters

 
Relationship between Low Bone Mass Measurements and Age in HIV-infected
Children and Adolescents on HAART
S Mora  , V Giacomet  , L Cafarelli , et al
 (12 CROI)
 Abstract

Oral

      Journal Papers, Abstracts, and Commentaries

  Candida Epiglottitis in an Adolescent with Acquired Immunodeficiency Syndrome.
Sharma N, Berman DM, Scott GB, Josephson G.
Pediatr Infect Dis J. 2005 Jan;24(1):91-92
 Abstract

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