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Delavirdine  (Rescriptor)
 
Journal Citations


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Pharmacokinetics
Drug/Drug Interactions
Resistance
Adverse Events
 Efficacy



 
Delavirdine Main Page ARV Drugs Main Page Home Page      
Last Update:  December 06, 2014
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General Reports
         
 
Solid lipid nanoparticles comprising internal Compritol 888 ATO, tripalmitin and cacao butter for encapsulating and
releasing stavudine, delavirdine and saquinavir.
 Kuo YC, Chung CY.
Colloids Surf B Biointerfaces. 2011
Abstract

Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: Introducing
a diketoacid functionality into delavirdine.
Wang Z, Vince R.  
Bioorg Med Chem. 2008 Feb 8
Abstract
 
Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by
polybutylcyanoacrylate, methylmethacrylate-sulfopropylmethacrylate, and solid lipid
nanoparticles.
 Kuo YC, Su FL
Int J Pharm. 2007 Mar 12
 Abstract
Pharmacokinetics
         
 
Population Pharmacokinetics of Delavirdine and N-Delavirdine in HIV-Infected Individuals.
Smith PF, Dicenzo R, Forrest A, et al
Clin Pharmacokinet. 2005;44(1):99-109.
 Abstract

Pharmacokinetics of Ritonavir and Delavirdine in Human Immunodeficiency Virus-Infected Patients.
Shelton MJ, Hewitt RG, Adams J, et al.
Antimicrob Agents Chemother 2003 May;47(5):1694-1699
 Abstract

  
Drug-Drug Interactions
         
  Pharmacokinetic interaction between amprenavir and delavirdine: Evidence of induced clearance by amprenavir.
Tran JQ, Petersen C, Garrett M, et al.
Clin Pharmacol Ther 2002 Dec;72(6):615-626
 Abstract		  
Resistance
 
  Effects of the G190A substitution of HIV reverse transcriptase on phenotypic susceptibility
of patient isolates to delavirdine.
Uhlmann EJ, Tebas P, Storch GA ,et al 
J Clin Virol. 2004 Nov;31(3):198-203.
 Abstract
 
  FULL-TEXT ARTICLE
 Delavirdine in Combination with Zidovudine in Treatment of Human Immunodeficiency Virus
Type 1-Infected Patients: Evaluation of Efficacy and Emergence of Viral Resistance in a
Randomized, Comparative Phase III Trial
Joly V , Moroni M, Concia E,
Antimicrob Agents Chemother  2000 Nov;44(11):3155-3157
  Paper
Adverse Events
 
  Delavirdine malabsorption in HIV-infected subjects with spontaneous
gastric hypoacidity.
Shelton MJ, Hewitt RG, Adams JM, et al.
J Clin Pharmacol 2003 Feb;43(2):171-9
 Abstract
Efficacy
 

FULL-TEXT ARTICLE
 Delavirdine in Combination with Zidovudine in Treatment of Human Immunodeficiency Virus
Type 1-Infected Patients: Evaluation of Efficacy and Emergence of Viral Resistance in a
Randomized, Comparative Phase III Trial
Joly V, Moroni M, Concia E, et al;
 Antimicrob Agents Chemother 2000 Nov;44(11):3155-3157
 Paper

FULL-TEXT ARTICLE