Medical Advocates
Pneumocystis jirovecii (carinii)
  Drugs
 
Clindamycin                        
Corticosteroids
Cotrimoxazole
 Corticosteroids
 Dapsone
Deferoxamine  
Ganciclovir
Pafuramidine
Pentamidine 
Pyrimethamine/Sulfadoxine		 Quinupristin-Dalfopristin
Sulfamethoxazole
Tacrolimus
TMP/SMX




 
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Last Update:  September 13, 2016
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Clindamycin
       
        Journal Papers, Abstracts, and Commentaries
 
  Successful treatment of severe pneumocystis pneumonia with clindamycin-primaquine in an HIV-negative patient.
Crisp HC, Stewart IJ, Blatz PJ, et al
South Med J. 2009 Nov;102(11):1161-3.
 Abstract
Cotrimoxazole
       
        Journal Papers, Abstracts, and Commentaries
 
 
Severe and long lasting cholestasis after high-dose co-trimoxazole treatment for Pneumocystis pneumonia in HIV-infected patients-a report of two cases.
Hanses F, Zierhut S, Schölmerich J, et al
Int J Infect Dis. 2009 Mar 17.
 Abstract

Cotrimoxazole Pneumocystis jiroveci pneumonia treatment failure: co-infection cytomegalovirus role?
Scemama J, Amathieu R, Tual L, Fessenmeyer C, et al  
Ann Fr Anesth Reanim. 2007 Apr 11;
 Abstract
Corticosteroids
       
        Journal Papers, Abstracts, and Commentaries
 
 

Successful treatment of severe pneumocystis pneumonia with clindamycin-primaquine in an HIV-negative patient.
Crisp HC, Stewart IJ, Blatz PJ, et al
South Med J. 2009 Nov;102(11):1161-3.
 Abstract

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection.
Ewald H, Raatz H, Boscacci R,  et al 
Cochrane Database Syst Rev. 2015 Apr 2;4:CD006150.
 Abstract

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV-infection.
Briel M, Bucher H, Boscacci R, Furrer H.
Cochrane Database Syst Rev. 2006 Jul 19;3:CD006150.
 Abstract

FULL-TEXT PDF ARTICLE
 Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection: a meta-analysis of randomised controlled trials.
Briel M, Boscacci R, Furrer H, Bet al 
BMC Infect Dis. 2005 Nov 7;5(1):101
 Paper
Dapsone
       
        Journal Papers, Abstracts, and Commentaries
 
  Toxicity and Efficacy of Daily Dapsone as Pneumocystis jiroveci Prophylaxis after Hematopoietic Stem Cell Transplantation: A Case-Control Study.
Sangiolo D, Storer B, Nash R,et al
Biol Blood Marrow Transplant. 2005 Jul;11(7):521-9.
Abstract
Deferoxamine
       

        Journal Papers, Abstracts, and Commentaries

  Action of deferoxamine against Pneumocystis carinii.
Clarkson AB Jr, Turkel-Parrella D, et al
Antimicrob Agents Chemother 2001 Dec;45(12):3560-5
 Abstract
Ganciclovir
       

        Journal Papers, Abstracts, and Commentaries

  An observational study of once weekly intravenous ganciclovir as CMV prophylaxis in heavily pre-treated chronic lymphocytic leukemia patients receiving subcutaneous alemtuzumab.
Visani G, Mele A, Guiducci B, et al 
Leuk Lymphoma. 2006 Dec;47(12):2542-6
 Abstract
Pafuramidine
       

        Journal Papers, Abstracts, and Commentaries

  Pafuramidine for Pneumocystis jiroveci pneumonia in HIV-infected individuals.
Chen D, Marsh R, Aberg JA
Expert Rev Anti Infect Ther. 2007 Dec;5(6):921-8.
 Abstract
Pentamidine
       

        Journal Papers, Abstracts, and Commentaries

 
Aerosolized pentamidine prophylaxis against AIDS-related Pneumocystis carinii pneumonia and its short- and long-term effects on pulmonary function in the Japanese.
Konishi M, Yoshimoto E, Takahashi K, et al
J Infect Chemother. 2003 Jun;9(2):178-182.
Abstract

The Pulmonary Effects of Long-term Exposure to Aerosol Pentamidine: A 5-Year Surveillance Study in HIV-Infected Patients.
Obaji J, Lee-Pack LR, Gutierrez C, Chan CK.
Chest. 2003 Jun;123(6):1983-7.
Abstract
 
Serial pentamidine levels in bronchial epithelial lining fluid after aerosol administration.
Yamamoto H, Koizumi T, Miyahara T, et al.
Respiration 2001;68(5):506-8
 Abstract

Pyrimethamine/Sulfadoxine
       

        Journal Papers, Abstracts, and Commentaries

  Association between a Specific Pneumocystis jiroveci Dihydropteroate Synthase Mutation and Failure of Pyrimethamine/Sulfadoxine Prophylaxis in Human Immunodeficiency Virus-
Positive and -Negative Patients.
Nahimana A, Rabodonirina M, Zanetti G, et al 
J Infect Dis. 2003 Oct 1;188(7):1017-23.
 Abstract
Quinupristin-Dalfopristin
       

          Journal Papers, Abstracts, and Commentaries

  In Vitro and In Vivo Effects of Quinupristin-Dalfopristin against Pneumocystis carinii.
Walzer PD, Ashbaugh A, Collins M, Cushion MT
Antimicrob Agents Chemother 2001 Nov;45(11):3234-7
Abstract
Sulfamethoxazole
       

         Journal Papers, Abstracts, and Commentaries

  Linking Pneumocystis jiroveci sulfamethoxazole resistance to the alleles of the DHPS gene using functional complementation in Saccharomyces cerevisiae.
Moukhlis R, Boyer J, Lacube P, et al  
Clin Microbiol Infect. 2009 Aug 10.
Abstract
Tacrolimus
       

         Journal Papers, Abstracts, and Commentaries

  FULL-TEXT ARTICLE
Pneumocystis pneumonia induced by treatment with low-dose tacrolimus and methylprednisolone in a patient with rheumatoid arthritis: a case report
Kato M, Tobino K, Fujimoto Y,  et al
BMC Res Notes. 2013 Dec 1;6:498
 Paper
Trimethoprim-Sulfamethoxazole
       

         Journal Papers, Abstracts, and Commentaries

 

FULL-TEXT ARTICLE
A Case of Pneumonia Caused by Pneumocystis jirovecii Resistant to Trimethoprim-Sulfamethoxazole.
Lee SM, Cho YK, Sung YM,
Korean J Parasitol. 2015 Jun;53(3):321-327.
Paper

Good outcome with trimethoprim 10 mg/kg/day-sulfamethoxazole 50 mg/kg/day for Pneumocystis jirovecii pneumonia in HIV infected patients.
Thomas M, Rupali P, Woodhouse A, Ellis-Pegler R.
Scand J Infect Dis. 2009 Aug 17:1-7
 Abstract

A Systematic Review of Two Different Trimetoprim-Sulfamethoxazole Regimens Used to Prevent Pneumocystis jirovecii and No Prophylaxis at All in Transplant Recipients:
Appraising the Evidence.
Di Cocco P, Orlando G, Bonanni L, et al
Transplant Proc. 2009 May;41(4):1201-3.
 Abstract

FULL TEXT PDF ARTICLE
Preventive effect of sulfamethoxasole-trimethoprim on Pneumocystis jiroveci pneumonia in patients with interstitial pneumonia.
Enomoto T, Azuma A, Matsumoto A
Intern Med. 2008;47(1):15-20.
 Paper
 
 
 

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