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Alternating Therapy
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Last Update:  March 27, 2018  
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General Reports
 
     Journal Papers, Abstracts, and Commentaries
 
 

Modification of Initial Highly Active Antiretroviral Therapy (HAART) Regimen in Paediatric HIV Patients.
Low YS, Islahudin F, Razali KAM, Adnan S.
Open AIDS J. 2018 Mar 12;12:11-19.
Abstract

Second- and Third-line Antiretroviral Therapy for Children and Adolescents: A Scoping Review.
 Lazarus E, Nicol S, Frigati L, et al 
Pediatr Infect Dis J. 2017 May;36(5):492-499
 Abstract

First-line antiretroviral drug discontinuations in children.
Fortuin-de Smidt M, de Waal R,  et al 
PLoS One. 2017 Feb 13;12(2):e0169762
 Abstract

Second and Third Line Antiretroviral Therapy for Children and Adolescents: A Scoping Review.
 Lazarus E, Nicol S, Frigati L, et al
Pediatr Infect Dis J. 2016 Dec 15.
 Abstract

Genotype-guided antiretroviral regimens in children with multi-drug resistant HIV-1 infection.
 Huerta-García G, Vazquez-Rosales JG, Mata-Marín JA, et al
 Pediatr Res. 2016 Mar 21.
 Abstract

Once-Daily Antiretroviral Therapy in a Cohort of HIV-Infected Children and Adolescents.
 Jiménez-Montero B, Beceiro J, de José-Gómez MI, et al
Pediatr Infect Dis J. 2014 Apr 17
 Abstract

Use of Nucleoside Reverse Transcriptase Inhibitor-only Regimens in HIV-infected Children and Adolescents.
 Neely M, Rutstein R, Del Bianco G,  et al
Pediatr Infect Dis J. 2013 Sep;32(9):e370
Abstract
Starting Therapy
 
     Journal Papers, Abstracts, and Commentaries
 
 
Early Antiretroviral Therapy in HIV-Infected Children Is Associated with Diffuse White Matter Structural Abnormality and Corpus Callosum Sparing.
 Ackermann C, Andronikou S, Saleh MG,  et al
AJNR Am J Neuroradiol. 2016 Aug 18.
 Abstract

Early antiretroviral therapy in children perinatally infected with HIV: a unique opportunity to implement immunotherapeutic approaches to prolong viral remission.
 Klein N, Palma P, Luzuriaga K, et al
Lancet Infect Dis. 2015 Jul 14
 Abstract

Outcomes of Infants Starting Antiretroviral Therapy in Southern Africa, 2004-2012.
 Porter M, Davies MA, Mapani MK, et al
J Acquir Immune Defic Syndr. 2015 Aug 15;69(5):593-601.Z
 Abstract

FULL-TEXT ARTICLE
 Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection.
 Mori M, Adland E, Paioni P, Swordy A, et al 
PLoS One. 2015 Jul 7;10(7):e0131591
Paper

Starting Treatment in Pediatric HIV Infection: Try to Clarify a Gray Area.
Prato M, Venturini E, Chiappini E, et al
Pediatr Infect Dis J. 2015 May;34(5 Suppl 1,
Abstract

Young age at start of antiretroviral therapy and negative HIV antibody results in HIV-infected children when suppressed.
Kuhn L, Schramm DB, Shiau S,  et al
AIDS. 2015 Apr 13.
 Abstract

Using CD4 Percentage and Age to Optimize Pediatric Antiretroviral Therapy Initiation.
 Yin DE, Warshaw MG, Miller WC,  et al 
Pediatrics. 2014 Sep 29. pii: peds.2014-0527
 Abstract
Early Initiation of Combination Antiretroviral Therapy in HIV-1-Infected Newborn Infants can Achieve Sustained Virologic Suppression with Low Frequency of CD4+ T-cells carrying HIV in Peripheral Blood.
Bitnun A, Samson L, Chun TW,  et al
Clin Infect Dis. 2014 Jun 9.
Abstract

Immediate antiretroviral therapy in young HIV-infected children: benefits and risks.
Collins IJ, Judd A, Gibb DM.
Curr Opin HIV AIDS. 2013 Nov 15
 Abstract

Optimal time for initiating antiretroviral therapy (ART) in HIV-infected, treatment-naive children aged 2 to 5 years old.
 Siegfried N, Davies MA, Penazzato M,  et al
Cochrane Database Syst Rev. 2013 Oct 10;10:CD010309.
 Abstract

Antiretroviral therapy increases thymic output in children with HIV.
 Sandgaard KS, Lewis J, Adams S, et al
 AIDS. 2013 Sep 25.
 Abstract

Early versus deferred antiretroviral therapy for children older than 1 year infected with HIV (PREDICT): a multicentre, randomised, open-label trial.
 Puthanakit T, Saphonn V, Ananworanich J,  et al
Lancet Infect Dis. 2012 Oct 8.
 Abstract

When to Start, What to Start and Other Treatment Controversies in Pediatric HIV Infection.
 T|urkova A, Webb RH, Lyall H.
Paediatr Drugs. 2012 Sep 27
 Abstract

Short- and Long-term Immunological and Virological Outcome in HIV-Infected Infants According to the Age at Antiretroviral Treatment Initiation.
Goetghebuer T, Le Chenadec J, Haelterman E,  et al
 Clin Infect Dis. 2011 Dec 23.
 Abstract

Discordance between CD4 cell count and CD4 cell percentage: implications for when to start antiretroviral therapy in HIV-1 infected children.
 HIV Paediatric Prognostic Markers Collaborative Study.
AIDS. 2010 Apr 9
 Abstract
Alternating Therapy
 

     Journal Papers, Abstracts, and Commentaries

 
A randomized controlled trial of intermittent compared with daily cotrimoxazole preventive therapy in HIV-infected children.
Zar HJ, Workman L, le Roux SM, et al
AIDS. 2010 Aug
Abstract
Treatment Interruption
 

     Journal Papers, Abstracts, and Commentaries

 
FULL-TEXT ARTICLE
 Mutations Related to Antiretroviral Resistance Identified by Ultra-Deep Sequencing in HIV-1 Infected Children under Structured Interruptions of HAART.
 Vazquez-Guillen JM, Palacios-Saucedo GC, Rivera-Morales LG,  et al
PLoS One. 2016 Jan 25;11(1):e0147591
 Paper

Factors associated with antiretroviral treatment interruption in human immunodeficiency virus (HIV)-1-infected children attending the Jos University Teaching Hospital, Jos, Nigeria.
 Ebonyi AO, Ejeliogu EU, Okpe SE,  et al
Niger Med J. 2015 Jan-Feb;56(1):43-7
 Abstract

Interruption of cART in Clinical Practice is Associated with an Increase in the Long-Term Risk of Subsequent Immunosuppression in HIV-1-Infected Children.
 Aupiais C, Faye A, Le Chenadec J,  et al
Pediatr Infect Dis J. 2014 Ju
 Abstract

FULL-TEXT ARTICLE
 The Immunological and Virological Consequences of Planned Treatment Interruptions in Children with HIV Infection.
 Klein N, Sefe D, Mosconi I,  et al
PLoS One. 2013 Oct 23;8(10):e76582.
 Paper
 
 Outcomes after reinitiating antiretroviral therapy in children randomized to planned treatment interruptions in the PENTA 11 Study.
 Bunupuradah T, Duong T, Compagnucci A, et al
AIDS. 2012 Nov 6.
Abstract

Impact of CD4 T Cell Count on the  Outcome of Planned Treatment Interruptions  in Early- Treated HIV-Infected Children.
Fortuny C, Noguera-Julian A, Alsina L, et al
Pediatr Infect Dis J. 2010 Oct 27
 Abstract

Evolution of Mitochondrial DNA Content After Planned Interruption of HAART in HIV-Infected Pediatric Patients.
Noguera A, Morén C, Rovira N, et al 
AIDS Res Hum Retroviruses. 2010 Aug 14.
 Abstract
Switching Therapy
 
     Journal Papers, Abstracts, and Commentaries
 
  HIV-1 Drug Resistance and Second-Line Treatment in Children Randomized to Switch at Low Versus Higher RNA Thresholds.
 Harrison L, Melvin A, Fiscus S, et al
J Acquir Immune Defic Syndr. 2015 Sep 1;70(1):42-53.
 Abstract

FULL TEXT ARTICLE
 A biregional survey and review of first-line treatment failure and second-line pediatric antiretroviral access and use in Asia and southern Africa.
TREAT Asia Pediatric HIV Observational Database (TApHOD);
J Int AIDS Soc. 2011 Apr 8;14(1):17
 Paper
Treatment Simplification
 
     Journal Papers, Abstracts, and Commentaries
 
  Successful simplification of protease inhibitor-based HAART with triple nucleoside regimens in children vertically infected with HIV.
 Palma P, Romiti ML, Cancrini C, et al 
AIDS. 2007 Nov 30;21(18):2465-2472.
 Abstract
Lipid Management
 
     Journal Papers, Abstracts, and Commentaries
 
  Effect of specific antiretroviral therapy (ART) drugs on lipid changes and the need for lipid management in children with HIV.
Rhoads MP, Lanigan J, Smith CJ, Lyall EG.
 J Acquir Immune Defic Syndr. 2011 Apr 14.
Abstract
Stopping Therapy
 
     Journal Papers, Abstracts, and Commentaries
 
  Long-Term Effects of Highly Active Antiretroviral Therapy on CD4(+) Cell Evolution among Children and Adolescents Infected with HIV: 5 Years and Counting.
 Patel K, Hernán MA, Williams PL, et al
Clin Infect Dis. 2008 Apr 2
 Abstract
Salvage Therapy
 
     Journal Papers, Abstracts, and Commentaries
 
  FULL TEXT PDF ARTICLE
 Predictive factors of virological success to salvage regimens in HIV-1 infected children.
Larru B, De Mendoza C, Bellon JM, et al
 BMC Infect Dis. 2007 Jun 10;7(1):55
Paper

   

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