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In vitro hypersusceptibility of human
immunodeficiency virus type 1 subtype C
protease to lopinavir.
Gonzalez LM, Brindeiro RM, Tarin M, et al
Antimicrob Agents Chemother. 2003 Sep;47(9):2817-22.
Abstract
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In vitro antiviral interaction of lopinavir with
other protease inhibitors.
Molla A, Mo H, Vasavanonda S, Han L
Antimicrob Agents Chemother 2002 Jul;46(7):2249-53
Abstract
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X-ray crystallographic
structure of ABT-378 (Lopinavir) bound to HIV-1 protease.
Stoll V, Qin W, Stewart KD,
Jakob C, et al
Bioorg Med Chem 2002 Aug;10(8):2803-6
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FULL-TEXT ARTICLE
In
vitro metabolism of the HIV-1 protease inhibitor ABT-378: species comparison
and metabolite identification.
Kumar GN, Jayanti V,
Lee RD, et al.
Drug Metab Dispos
1999 Jan;27(1):86-91
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Human
serum attenuates the activity of protease inhibitors toward wild-type
and
mutant human immunodeficiency virus
Molla A,
Vasavanonda S, Kumar G, Sham HL, et al.
Virology
1998 Oct 25;250(2):255-62
Abstract |
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FULL-TEXT ARTICLE
In
vitro selection and characterization of human immunodeficiency virus
type 1
variants with increased resistance to ABT-378, a novel protease inhibitor.
Carrillo A, Stewart KD, Sham HL, et al.
J Virol 1998 Sep;72(9):7532-41
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Human Immunodeficiency Virus Type 1 Genotypic and
Pharmacokinetic
Determinants of the Virological Response to
Lopinavir-Ritonavir-Containing
Therapy in Protease
Inhibitor-Experienced Patients.
Masquelier B, Breilh D, Neau D, et al.
Antimicrob Agents Chemother 2002 Sep;46(9):2926-2932
Abstract
Pharmacokinetics of amprenavir and lopinavir in combination with
nevirapine
in highly pretreated HIV-infected patients.
Fătkenheuer G, Römer K, Kamps
R, et al
AIDS, 2001:Vol 15, No 17 2334-2355
Abstract
ABT 378/r: a novel inhibitor of HIV-1 protease in
haemodialysis.
Izzedine H, Launay-Vacher V, Legrand M, et al.
AIDS 2001 Mar 30;15(5):662-4
Abstract
FULL-TEXT ARTICLE
Potent
inhibition of the cytochrome P-450 3A-mediated human liver
microsomal
metabolism
of a novel HIV protease inhibitor by ritonavir:
A positive drug-drug
interaction.
Kumar GN, Dykstra J, Roberts EM, Jayanti
VK, Hickman D, et al.
Drug Metab Dispos 1999 Aug;27(8):902-8
Paper
FULL-TEXT ARTICLE
ABT-378,
a highly potent inhibitor of the human immunodeficiency virus
protease.
Sham HL, Kempf DJ, Molla A, Marsh KC, Kumar GN, Chen CM, et al
Antimicrob Agents
Chemother 1998 Dec;42(12):3218-24
Paper
FULL-TEXT ARTICLE
Pharmacokinetic enhancement of inhibitors of the human immunodeficiency
virus protease by coadministration with ritonavir.
Kempf DJ, Marsh KC, Kumar G, et al;
Antimicrob Agents Chemother
1997 Mar;41(3):654-60
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