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Saquinavir (Invirase/Fortovase)

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New and Noteworthy

November 2015

The HIV-protease inhibitor saquinavir reduces proliferation, invasion and clonogenicity in cervical cancer cell lines.
Bandiera E, Todeschini P, Romani C, et al Oncol Lett. 2016 Oct;12(4):2493-2500

Saquinavir Induced Suicidal Death of Human Erythrocytes.
Waibel S, Bissinger R, Bouguerra G, et ak Cell Physiol Biochem. 2015;37(5):1973-1982.

Drug Alerts

IMPORTANT DRUG INTERACTION ADMINISTRATION WARNING
New Saquinavir Drug Interaction Information and Warnings on Coadministration of
Invirase/Ritonavir and Digoxin
USFDA
June 11, 2008
Product Information
IMPORTANT DRUG INTERACTION WARNING
Drug-Induced Hepatitis with Marked Transaminase Elevations Has Been Observed in Healthy
Volunteers Receiving Rifampin 500 mg Once Daily in Combination with Ritonavir 100 mg/
Saquinavir 1000 mg Twice Daily (Ritonavir Boosted Saquinavir)
Birgerson L
February 2005
PDF Product Information Letter

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