Medical Advocates for Social Justice
Didanosine (Videx)
 
Perinatal Index

Adverse Events
 Monotherapy
Combination Therapies






 
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Last Update:  February 09, 2016
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Adverse Events
       

  Journal Papers, Abstracts, and Commentaries

  Risk of cancer in children exposed to didanosine in utero.
 Hleyhel M, Goujon S, Delteil C, et al  
AIDS. 2016 Feb 5.
Abstract
Monotherapy
       
Pharmacokinetics

            Journal Papers, Abstracts, and Commentaries

  Pharmacokinetics of didanosine in antepartum and postpartum human |immunodeficiency
virus–infected pregnant women and their neonates:an AIDS clinical trials group study.
Wang Y, Livingston E, Patil S, McKinney RE, et al.
J Infect Dis 1999 Nov;180(5):1536-41
Abstract
Combination Therapy
       

DDI/ZDV vs DDI/ZDV/NVP

Efficacy

     Journal Papers, Abstracts, and Commentaries

  Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients
with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. NIAID Clinical Trials
Group Protocol 241 Investigators.
D’Aquila RT, Hughes MD, Johnson VA, et al.  
 Ann Intern Med 1996 Jun 15;124(12):1019-30  
Abstract 

DDI/NFV/D4T

Pharmacokinetics

         Journal Papers, Abstracts, and Commentaries

  Pharmacokinetics of Stavudine and Didanosine coadministered with nelfinavir in human
immunodeficiency virus-exposed neonates.
Rongkavilit C, Thaithumyanon P, Chuenyam, T, et al.
Antimicrob Agents Chemother. 2001 Dec;45(12):3585-90.
Abstract
   
  Pharmacokinetics of Stavudine and Didanosine coadministered with nelfinavir in human
immunodeficiency virus-exposed neonates.
Rongkavilit C, Thaithumyanon P, Chuenyam, T, et al.
Antimicrob Agents Chemother. 2001 Dec;45(12):3585-90.
Abstract

         Conference Reports, Abstracts, and Posters

  Safety and Pharmacokinetics of Stavudine and Didanosine when  Co-Administered
with Nelfinavir in HIV-Exposed Neonates
(41 ICAAC)   
Abstract 

DDI/ZDV/NVP vs DDI/ZDV

Efficacy

          Journal Papers, Abstracts, and Commentaries

  Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in
patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial.
NIAID Clinical Trials Group Protocol 241 Investigators. D’Aquila RT, Hughes MD, et al. 
MS Ann Intern Med 1996 Jun 15;124(12):1019-30
Abstract
 

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Didanosine Perinatal Data