HIV Infection/Disease Symptom Diarrhea

Medical Advocates
HIV Infection/Disease

Diarrhea

General Reports
Pathogens
Risk Factors
Patient Perceptions
Drug-Related Diarrhea
Management
Quality of Life
National Studies

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Last Update: April 19, 2015
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General Reports

Journal Papers, Abstracts, and Commentaries

Human Immunodeficiency Virus-Associated Diarrhea: Still an Issue in the Era of Antiretroviral Therapy.
Dikman AE, Schonfeld E, Srisarajivakul NC, Poles MA.
Dig Dis Sci. 2015 Mar 14
Abstract

Unexplained diarrhoea in HIV-1 infected individuals.
Oude Munnink BB, Canuti M, Deijs M, et al
BMC Infect Dis. 2014 Jan 13;14(1):22.
Abstract

Intestinal spirochetosis as a cause of chronic diarrhoea in patients with HIV infection: case report and review of the literature.
Ena J, Simón-Aylón A, Pasquau F
Int J STD AIDS. 2009 Oct 20
Abstract

FULL-TEXT ARTICLE
Etiological agents of diarrhea in patients infected by the human immunodeficiency virus-1: a review.
Rossit AR, Gonçalves AC, Franco C, Machado RL
Rev Inst Med Trop Sao Paulo. 2009 Mar-Apr;51(2):59-65
Paper

Systematic Review of Strategies to Measure HIV-Related Diarrhea.
Tinmouth J, Kandel G, Tomlinson G, et al
HIV Clin Trials. 2007 May-Jun;8(3):155-63.
Abstract

Etiology of Chronic Diarrhea in Antiretroviral-Naive Patients with HIV Infection Admitted to Norodom Sihanouk Hospital, Phnom Penh, Cambodia.
Chhin S, Harwell JI, Bell JD, et al
Clin Infect Dis. 2006 Oct 1;43(7):925-32.
Abstract

Diarrhea in patients with AIDS.
Morpeth SC, Thielman NM.
Curr Treat Options Gastroenterol. 2006 Feb;9(1):23-37.
Abstract

Chronic Diarrhea and AIDS: Insights into Studies with Non-Human Primates.
Sestak K.
Curr HIV Res. 2005 Jul;3(3):199-205.
Abstract

Infectious diarrhea
Mottet C, El Wafa AA, Cavassini M, D’Acremont V, Delarive J.
Rev Med Suisse. 2005 Jan 19;1(3):209-10, 213-7.
Abstract

Etiologies and Manifestations of Persistent Diarrhea in Adults with HIV-1 Infection:A Case-Control Study in Lima, Peru.
Carcamo C, Hooton T, Wener MH, et al
J Infect Dis. 2005 Jan 1;191(1):11-9.
Abstract

Evaluation of Chronic Diarrhea in Patients with Human Immunodeficiency Virus Infection.
Oldfield EC 3rd.
Rev Gastroenterol Disord 2002 Autumn;2(4):176-188
Abstract

Pathogens

Conference Reports, Abstracts, and Posters

Cryptosporidiosis in HIV- infected persons presenting with diarrhea in Jos, North central
Nigeria
Danung M.L., Badung B.P., Mu’azu M.A., et al
(XVI International AIDS Conference)
Abstract

Prevalence of Salmonella and Shigella species in HIV/AIDS patients with diarrhoea in Lagos, Nigeria
CT Oparaugo, E O Idigbe, J I Onyewuche, E B Adetiloye
(15IAC)
Abstract

Spectrum of parasitic infections in AIDS associated diarrhoea
AS Chowdhary, M Joshi
(15IAC)
Abstract

Spectrum of parasitic pathogens in AIDS related diarrhea in a tertiary care hospital, Belgaum, India
M B Mutnal, M B Nagamoti, C S Patil
(15IAC)
Abstract

Pathogens associated with diarrhea among persons with and without HIV in rural Uganda
J Mermin, A Kigozi, S Malamba, et al
(14IAC)
Abstract

Duodenal HIV-1 RNA load is increased in both HIV patients with an opportunistic intestinal pathogen or pathogen negative diarrhoea
P McKenna, B Gazzard, P Hayes, et al.
(14IAC)
Abstract

Risk Factors

Journal Papers, Abstracts, and Commentaries

FULL-TEXT ARTICLE
Failure to Eradicate Isospora belli Diarrhoea Despite Immune Reconstitution in Adults with HIV – A Case Series.
Boyles TH, Black J, Meintjes G, Mendelson M.
PLoS One. 2012;7(8):e42844..
Paper

Risk factors in HIV-associated diarrhoeal disease: the role of drinking water, medication and immune status.
Eisenberg J N S, Wade T J, Charles S, et al.
Epidemiol Infect 2002 Feb;128(1):73-81
Abstract

Patient Perceptions

            Conference Reports, Abstracts, and Posters

Traditional beliefs of diarrhoeal illness in children in an area of high HIV seroprevalence – implications for design and interpretation of epidemiological surveys
S Kauchali, N Rollins, G Solarsh
(14IAC)
Abstract

Drug-Related Diarrhea

GW433908

          Conference Reports, Abstracts, and Posters

GW433908 is associated with a significantly lower incidence of drug-related diarrhea and less use of antidiarrheals compared to nelfinavir in chronic HIV-infected antiretroviral therapy
naïve subjects
G Faetkenheuer, C Walworth, G Frechette,
(15IAC)
Abstract

Lopinavir

          Journal Papers, Abstracts, and Commentaries

Differences in rates of diarrhea in patients with human immunodeficiency virus receiving lopinavir-ritonavir or nelfinavir.
Guest JL, Ruffin C, Tschampa JM, et al
Pharmacotherapy. 2004 Jun;24(6):727-35.
Abstract

Nelfinavir

          Journal Papers, Abstracts, and Commentaries

Differences in rates of diarrhea in patients with human immunodeficiency virus receiving lopinavir-ritonavir or nelfinavir.
Guest JL, Ruffin C, Tschampa JM, et al
Pharmacotherapy. 2004 Jun;24(6):727-35.
Abstract

The use of calcium carbonate in nelfinavir-associated diarrhoea in HIV-1-infected patients.
Jensen-Fangel S, Justesen US, Black FT, et al
HIV Med 2003 Jan;4(1):48-52
Abstract

            Conference Reports, Abstracts, and Posters

Management of nelfinavir-related diarrhoea
C R Fumaz, E Negredo, J Puig, et al.
(14IAC)
Abstract

Evaluation of pancrelipase (ultrase mt-20) for the symptomatic control of nelfinavir-
associated diarrhea
S A Tuscher, T Greenough, A Stein, et al
(14IAC)
Abstract

Management

General Management Challenges

          Journal Papers, Abstracts, and Commentaries

Etiology and Pharmacologic Management of Noninfectious Diarrhea in HIV-Infected Individuals in the HAART Era.
Macarthur RD, Dupont HL.
Clin Infect Dis. 2012 Jun 14..
Abstract

Treatment of HIV-Associated Diarrhea with Curcumin.
Conteas CN, Panossian AM, Tran TT, Singh HM.
Dig Dis Sci. 2008 Dec 3
Abstract

Antimotility agents for chronic diarrhoea in people with HIV/AIDS.
Nwachukwu CE, Okebe JU.
Cochrane Database Syst Rev. 2008 Oct 8;(4):CD005644.
Abstract

Randomized Controlled Trial of Zinc Supplementation for Persistent Diarrhea in Adults With HIV-1 Infection.
Carcamo C, Hooton T, Weiss NS, et al
J Acquir Immune Defic Syndr. 2006 Aug 24
Abstract

         Conference Reports, Abstracts, and Posters

Symptom management of diarrhea in HIV/AIDS
M J Hamilton, E Sefcik, Y Tsai, et al
(15IAC)
Abstract

Adequate zinc intake is strongly associated with lower incidence of diarrhea in HIV+ drug users
A Campa, F Huffman, S Sales, et al
(15IAC)
Abstract

STEP-WISE INTERVENTION FOR THE MANAGEMENT OF NELFINAVIR (NFV)-ASSOCIATED DIARRHEA
A. Rachlis, M.J. Gill, J.G. Baril, et al
(2nd IAS)
Abstract

Evaluation of pancrelipase (ultrase mt-20) for the symptomatic control of nelfinavir-associated diarrhea
S A Tuscher, T Greenough, A Stein, et al
(14IAC)
Abstract

Drugs

Crofelemer

Journal Papers, Abstracts, and Commentaries

Crofelemer: In HIV Associated Diarrhea and Secretory Diarrhea- A Patent Perspective.
Biswal S.
Recent Pat Antiinfect Drug Discov. 2015 Apr 8.
Abstract

Efficacy and Safety of Crofelemer for Noninfectious Diarrhea in HIV-Seropositive Individuals (ADVENT Trial): A Randomized, Double-Blind, Placebo-Controlled, Two-Stage Study.
Macarthur RD, Hawkins TN, Brown SJ, et al
HIV Clin Trials. 2013 Nov-Dec;14(6):261-73
Abstract

FULL-TEXT ARTICLE
Crofelemer for the treatment of chronic diarrhea in patients living with HIV/AIDS.
Patel TS, Crutchley RD, Tucker AM, et al
HIV AIDS (Auckl). 2013 Jul 15;5:153-62.
Paper

Crofelemer: A Review of its Use in the Management of Non-Infectious Diarrhoea in Adult Patients with HIV/AIDS on Antiretroviral Therapy.
Frampton JE.
Drugs. 2013 Jun 27.
Abstract

Crofelemer, a novel antisecretory agent approved for the treatment of HIV-associated diarrhea.
Yeo QM, Crutchley R, Cottreau J, Tucker A, Garey KW.
Drugs Today (Barc). 2013 Apr;49(4):239-52
Abstract

Mesalamine
Journal Papers, Abstracts, and Commentaries

Double-Blind Pilot Study of Mesalamine vs. Placebo for Treatment of Chronic Diarrhea and Nonspecific Colitis in Immunocompetent HIV Patients.
Rodriguez-Torres M, Rodriguez-Orengo JF, Rios-Bedoya CF, et al
Dig Dis Sci. 2006 Jan;51(1):161-7
Abstract

Quality of Life

Journal Papers, Abstracts, and Commentaries

Association between diarrhea and quality of life in HIV-infected patients receiving highly active antiretroviral therapy.
Tramarin A, Parise N, Campostrini S, et al.
Qual Life Res. 2004 Feb;13(1):243-50.
Abstract

National Studies

Cambodia
Journal Papers, Abstracts, and Commentaries

Etiology of Chronic Diarrhea in Antiretroviral-Naive Patients with HIV Infection Admitted to Norodom Sihanouk Hospital, Phnom Penh, Cambodia.
Chhin S, Harwell JI, Bell JD, et al
Clin Infect Dis. 2006 Oct 1;43(7):925-32.
Abstract

India

Conference Reports, Abstracts, and Posters

	Coccidian parasites in HIV seropositive patients with diarrhea in Pune, India Kulkarni S., Kairon R, Kale VA, et al (XVI International AIDS Conference) Abstract
	Cryptosporidiosis in HIV- infected persons presenting with diarrhea in Jos, North central Nigeria Danung M.L., Badung B.P., Mu’azu M.A., et al (XVI International AIDS Conference) Abstract
	Diarrhea in HIV-infected adults in Karnataka, India: evaluation of risk factors and etiology Becker M., Cohen C., Cheang M., et al (XVI International AIDS Conference) Abstract
	Chronic diarrhea as presenting feature of abdominal tuberculosis in HIV/AIDS patients in a tertiary care center in India Pazare A., Mathew Davis A., Atre Singh D. (XVI International AIDS Conference) Abstract

Nigeria
Journal Papers, Abstracts, and Commentaries

Diarrhea prevention in people living with HIV: an evaluation of a point-of-use water quality intervention in Lagos, Nigeria.
Barzilay EJ, Aghoghovbia TS, Blanton EM, et al
AIDS Care. 2011 Mar;23(3):330-9.
Abstract

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Diarrhea