Medical Advocates
HAART/ART/cART
 
Drug/Substance Interactions

ARV Drug Interactions Database
 General Reports 
 Anticonvulsant Drugs      
Antineoplastic Drugs      
Addiction Management Drugs
 Metabolic Management Drugs
Transplantation Drugs
Psychotropic Drugs
Statins
Recreational Drugs/Substances
 


Specific HIV ARV drug interactions are
indexed under the applicable drug



 
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Last Update:  March 25, 2015  
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General Reports
 

     Journal Papers, Abstracts, and Commentaries
 
Drug-Drug Interactions: Antiretroviral Drugs and Recreational Drugs.
Staltari O, Leporini C, Caroleo B,
Recent Pat CNS Drug Discov. 2014 Nov 26
 Abstract

Pharmacokinetic and Pharmacodynamic Drug Interactions Between Antiretrovirals and Oral Contraceptives.
 Tittle V, Bull L, Boffito M, Nwokolo N. 
Clin Pharmacokinet. 2014 Oct 21.
 Abstract

Significant interaction between activated charcoal and antiretroviral therapy leading to subtherapeutic drug concentrations, virological breakthrough and development of resistance.
Tseng AL, la Porte C, Salit IE.
Antivir Ther. 2013 Sep 26.
Abstract

Drug-drug interactions in HIV therapy: is it all clear?
Burger D, Back D.
Antivir Ther. 2013 Sep 26.  
 Abstract

Important Drug-Drug Interactions in HIV-Infected Persons on Antiretroviral Therapy: An Update on New Interactions Between HIV and Non-HIV Drugs.
Tseng A, Foisy M.
 Curr Infect Dis Rep. 2011 Nov 30..
 Abstract

Drug-Drug Interactions with HIV Treatments
Mossdorf E, Marzolini C, Fasel D,  et al
 Praxis (Bern 1994). 2011 Sep 21;100(19):1193-6
 Abstract

Approaches for understanding and predicting drug interactions in human immunodeficiency virus-infected patients.
Jiménez-Nácher I, Alvarez E, Morello J,  et al
  xpert Opin Drug Metab Toxicol. 2011 Feb 23.
 Abstract

Emerging antiretroviral drug interactions.
Pham PA, Flexner C.
J Antimicrob Chemother. 2010 Dec 5.
Abstract

Recognition and Management of Significant Drug Interactions in HIV Patients: Challenges in Using Available Data to Guide Therapy.
Pau AK, Boyd SD.
Clin Pharmacol Ther. 2010 Jul 28.
 Abstract

Recognition of Risk for Clinically Significant Drug Interactions among HIV-Infected Patients Receiving Antiretroviral Therapy.
Evans-Jones JG, Cottle LE, Back DJ,  et al
Clin Infect Dis. 2010 Apr 9
 Abstract

Quality of the antiretrovirals drug interactions database.
Villacorta Linaza P, Ruano Camps R, et al 
Med Clin (Barc). 2010 Mar 18.
 Abstract

Drug interactions with new and investigational antiretrovirals.
Brown KC, Paul S, Kashuba AD.
 Clin Pharmacokinet. 2009;48(4):211-41
 Abstract

Antiretroviral drug interactions: often unrecognized, frequently unavoidable, sometimes unmanageable.
Seden K, Back D, Khoo S. 
J Antimicrob Chemother. 2009 Apr 27.
Abstract

Serious adverse events derived from the drug interactions of antiretroviral therapy.
Morales Conejo M, Moreno Cuerda VJ, et al
Rev Clin Esp. 2008 Dec;208(11):557-60.
Abstract
 
Drug-drug interactions with newer antiretroviral agents.
Aberg JA.
Top HIV Med. 2008 Dec-2009 Jan;16(5):146-50.
 Abstract

Drug interactions in the management of HIV infection: an update.
Robertson SM, Penzak SR, Pau A.
Expert Opin Pharmacother. 2007 Dec;8(17):2947-2963
 Abstract
 
A WEEK-IN-REVIEW FEATURED REPORT
 Pharmacokinetic drug interactions between opioid agonist therapy and antiretroviral medications: implications and management for clinical practice.
Bruce RD, Altice FL, Gourevitch MN, Friedland GH.
J Acquir Immune Defic Syndr. 2006 Apr 15;41(5):563-72.
 Abstract
 
FULL-TEXT PDF ARTICLE
Drug-Drug Interactions and the Pharmacotherapy of HIV Infection.
 Kashuba AD.
 Top HIV Med. 2005 Jun-Jul;13(2):64-9.
Paper
 
Drug interactions between antiretroviral drugs and comedicated agents.
 de Maat MM, Ekhart GC, Huitema AD, et al
 Clin Pharmacokinet. 2003;42(3):223-82.
 Abstract
 
Drug interactions with antiretroviral agents
Furlan V, Taburet AM.
 Therapie. 2001 May-Jun;56(3):267-71.
Abstract
 
     Conference Reports, Abstracts, and Posters
 
  A WEEK IN REVIEW FEATURED REPORT
POSTER
 Drug interactions that really matter.
Khoo SH.
(Ninth International Congress on Drug Therapy in HIV Infection)
PDF Poster
Antineoplastic Drugs
 
     Journal Papers, Abstracts, and Commentaries

 
Life-threatening interaction between antiretroviral therapy and vinblastine in HIV-associated multicentric Castleman’s disease.
 Kotb R, Vincent I, Dulioust A, Peretti D,  et al   
 Eur J Haematol. 2006 Jan 12;
 Abstract

Interactions Between Antiretrovirals and Antineoplastic Drug Therapy.
 Antoniou T, Tseng AL.
 Clin Pharmacokinet. 2005;44(2):111-145.
 Abstract

Drug interactions with antiretroviral agents
Furlan V, Taburet AM.
 Therapie. 2001 May-Jun;56(3):267-71.
Abstract
Anticonvulsant/CNS Drugs
 

     Journal Papers, Abstracts, and Commentaries
 
 
Anticonvulsant and antiretroviral interactions.
 Liedtke MD, Lockhart SM, Rathbun RC.et al  
Ann Pharmacother. 2004 Mar;38(3):482-9
 Abstract

Concurrent Use of Antiretrovirals and Anticonvulsants in Human Immunodeficiency Virus (HIV) Seropositive Patients.
 Romanelli F, Pomeroy C
 Curr Pharm Des 2003;9(18):1433-9
 Abstract
 
Seizures in HIV-seropositive individuals: epidemiology and treatment.
 Romanelli F, Ryan M.
CNS Drugs 2002;16(2):91-8
Abstract
 
Therapeutic dilemma: the use of anticonvulsants in HIV-positive individuals.
 Romanelli F, Jennings HR, Nath A, et al.
Neurology 2000 Apr 11;54(7):1404-7
Abstract

HIV Metabolic Adverse Events Management Drugs
 

    Journal Papers, Abstracts, and Commentaries

  Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection.
 Fichtenbaum CJ, Gerber JG.
Clin Pharmacokinet. 2002;41(14):1195-211.
 Abstract
Addiction Management Drugs
 
General Reports

      Journal Papers, Abstracts, and Commentaries

 
A review of pharmacological interactions between HIV or hepatitis C virus medications and opioid agonist therapy: implications and management for clinical practice.
 Bruce RD, Moody DE, Altice FL,  et al
Expert Rev Clin Pharmacol. 2013 May;6(3):249-69
 Abstract

Pharmacokinetic drug interactions between opioid agonist therapy and antiretroviral medications:implications and management for clinical practice.
Bruce RD, Altice FL, Gourevitch MN, Friedland GH.
J Acquir Immune Defic Syndr. 2006 Apr 15;41(5):563-72.
 Abstract

Drug interactions associated with HAART: focus on treatments for addiction and recreational drugs.
 Faragon JJ, Piliero PJ.
 AIDS Read. 2003 Sep;13(9):433-4, 437-41, 446-50.
Abstract
 
Methadone   
 
           Journal Papers, Abstracts, and Commentaries
 

  Methadone and antiretroviral medications, part II.
 Gourevitch MN, Friedland GH.
 AIDS Clin Care. 1999 May;11(5):37, 43, 45-6.
 Abstract
Organ Transplantation Drugs
 
Tacrolimus 

          Conference Reports, Abstracts, and Posters

  Management of Drug-to-drug Interactions between Tacrolimus and HAART
 E Teicher , AM Taburet , I Vincent, et al
(12 CROI)
 Abstract
Psychotropic Drugs
 

      Journal Papers, Abstracts, and Commentaries

  Significant interactions with new antiretrovirals and psychotropic drugs.
Tseng AL, Foisy MM.et al
Ann Pharmacother. 1999 Apr;33(4):461-73.
 Abstract
Statins
 

      Journal Papers, Abstracts, and Commentaries

 
A WEEK-IN-REVIEW FEATURED REPORT
Devolving of statin prescribing to general practitioners for HIV-infected patients receiving antiretroviral therapy.
Benn PD, Miller RF, Evans L, Minton J, Edwards SG. 
Int J STD AIDS. 2009 Mar;20(3):202-4
 Abstract

Antiretroviral and statin drug-drug interactions.
Ray GM.
Cardiol Rev. 2009 Jan-Feb;17(1):44-7.
 Abstract
Recreational Drugs/Substances
 

     Journal Papers, Abstracts, and Commentaries

The Influence of Different Types of Alcoholic Beverages on Disrupting HAART Outcome.
Míguez-Burbano MJ, Lewis JE, et al
Alcohol Alcohol. 2009 May 18.
Abstract

Prevalence and Clinical Implications of Interactive Toxicity Beliefs Regarding Mixing Alcohol and Antiretroviral Therapies among People Living with HIV/AIDS.
Kalichman SC, Amaral CM, White D, et al
 AIDS Patient Care STDS. 2009 May 4
 Abstract

Drug interactions associated with HAART: focus on treatments for addiction and recreational drugs.
Faragon JJ, Piliero PJ.
 AIDS Read. 2003 Sep;13(9):433-4, 437-41, 446-50.
Abstract

Interactions between recreational drugs and antiretroviral agents.
Antoniou T, Tseng AL.
Ann Pharmacother. 2002 Oct;36(10):1598-613.
 Abstract

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