Medical Advocates
Dolutegravir
(Tivicay/S/GSK1349572) |
Last
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December 08, 2014
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A WEEK-IN-REVIEW FEATURED REPORT
POSTER
HIV resistance to dolutegravir (DTG) simultaneously diminishes viral DNA
integration into host cells and viral replication fitness: implications
for HIV reservoirs
T. Mesplede, P. Quashie M. Oliveira, M. Wainberg
Poster
Abstract
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POSTER
Secondary resistance mutations in the R263K integrase inhibitor resistance
pathway
T. Mesplède, M.A. Wares, N. Osman, P.K. et ak
Paper
Abstract
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Dolutegravir is non-inferior to raltegravir and shows durable response
through 96 weeks: results from the SPRING-2 trial
F. Raffi, H. Jaeger, D. Motta, et al
Abstract
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Once-daily
dolutegravir (DTG; S/GSK1349572) has a renal safety profile comparable to
raltegravir (RAL) and efavirenz in antiretroviral (ART)‑naïve adults: 48
week results from SPRING-2 (ING113086) and SINGLE (ING114467)
L.D. Curtis, S. Min, G. Nichols, et al
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Dolutegravir (DTG)
is superior to raltegravir (RAL) in ART-experienced, integrase naive
subjects: week 48 results from SAILING (ING111762)
P. Cahn, A.L. Pozniak, H. Mingrone3,et
al
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Pharmacokinetics,
safety and efficacy of dolutegravir (DTG; S/GSK1349572) in HIV-1-positive
adolescents:
preliminary analysis from IMPAACT P1093
R. Hazra, R. Viani, E. Acosta, et al
Abstract
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A WEEK-IN-REVIEW FEATURED REPORT
Once-daily
dolutegravir (DTG; S/GSK1349572) is non-inferior to raltegravir (RAL) in
antiretroviral‑naive adults: 48 week results from SPRING-2 (ING113086)
F. Raffi, A. Rachlis2 H.-J. Stellbrink, et al
Abstract
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Increasing patient
compliance in SPRING-1 phase IIb HIV clinical trial in ART-naïve patients
with dolutegravir (DTG, S/GSK1349572)
J. Harris, S. Hughes, C. Brothers
Abstract
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Rapid, robust and
sustained antiviral response with once-daily (QD) dolutegravir (DTG,
S/GSK1349572), a next generation integrase inhibitor (INI) in combination
therapy in antiretroviral-naïve adults: 48 week results from SPRING-1
(ING112276)
J. Van Lunzen, F. Maggiolo, B. Phung, et al
Abstract
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No impact of HIV
integrase polymorphisms at position 101 and 124 on in vitro resistance
isolation with dolutegravir (DTG, S/GSK1349572), a potent next generation
HIV integrase inhibitor
T. Seki, S. Miki, M. Kobayashi, T. Yoshinaga
Abstract
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Safety profile of
dolutegravir (DTG, S/GSK1349572), in combination with other antiretrovirals
in antiretroviral (ART)-naïve and ART-experienced adults from two phase IIb
studies
S. Min, A. Carrod, L. Curtis, C. Stainsby
Abstract
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