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MTCT Syphilis

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Perinatal Disease Index Main New and Noteworthy Home Page

Last Update:  November 16, 2007 

General Reports
 

        Journal Papers, Abstracts, and Commentaries

 
Do Targeted HIV Programs Improve Overall Care for Pregnant Women?: Antenatal
Syphilis Management in Zambia Before and After Implementation of Prevention of
Mother-to-Child HIV Transmission Programs.
 Potter D, Goldenberg RL, Chao A, et al  
J Acquir Immune Defic Syndr. 2007 Nov 1;
Abstract
 
The need and plan for global elimination of congenital syphilis.
Schmid GP, Stoner BP, Hawkes S, Broutet N.
Sex Transm Dis. 2007 Jul;34(7 Suppl):S5-10
 Abstract
 
The elimination of congenital syphilis: a comparison of the proposed World Health Organization
action plan for the elimination of congenital syphilis with existing national maternal and
congenital syphilis policies.
Hossain M, Broutet N, Hawkes S.
Sex Transm Dis. 2007 Jul;34(7 Suppl):S22-30.
 Abstract
 
Managing congenital syphilis again? The more things change ...
Chakraborty R, Luck S.
Curr Opin Infect Dis. 2007 Jun;20(3):247-52.
Abstract
 
FULL TEXT ARTICLE
Is congenital syphilis really congenital syphilis?
Li Y, Gonik B.
Infect Dis Obstet Gynecol. 2006 Sep;14(3):81629.
Paper
 
Issues of congenital syphilis in the past twenty years. I. Etiology, epidemiology and
diagnosis
Zákoucká H, Kremenová S, Kremen J.
Klin Mikrobiol Infekc Lek. 2006 Apr;12(2):44-50
 Abstract
 
Issues of congenital syphilis in the past twenty years. II. Clinical picture
Kremenová S, Zákoucká H, Kremen J.
Klin Mikrobiol Infekc Lek. 2006 Apr;12(2):51-7
 Abstract
 
Syphilis in pregnancy and the neonatal period.
Doroshenko A, Sherrard J, Pollard AJ.
Int J STD AIDS. 2006 Apr;17(4):221-7;
Abstract
 
The continuing scourge of congenital syphilis in 21st century: a case report
 Gurlek A, Alaybeyoglu NY, Demir CY, et al
 Int J Pediatr Otorhinolaryngol. 2005 Aug;69(8):1117-21.
 Abstract
 
Syphilis and pregnancy
Mandelbrot L, Marcollet A.
Rev Prat. 2004 Feb 29;54(4):392-5.
 Abstract
 
Congenital syphilis: identification of two distinct profiles of maternal characteristics
associated with risk.
Lago EG, Rodrigues LC, Fiori RM, Stein AT. et al
Sex Transm Dis. 2004 Jan;31(1):33-7.
 Abstract
 
Universal antenatal screening for syphilis: is it still justified economically? A 10-year retrospective
analysis.
Kiss H, Widhalm A, Geusau A, Husslein P. et al
Eur J Obstet Gynecol Reprod Biol. 2004 Jan 15;112(1):24-8.
Abstract

Forgotten but not gone: the continuing scourge of congenital syphilis.
 Walker DG, Walker GJ.
Lancet Infect Dis 2002 Jul;2(7):432-6
 Abstract

  
Diagnosis
 

       Journal Papers, Abstracts, and Commentaries

 
Analysis of the operational costs of using rapid syphilis tests for the detection of maternal
syphilis in Bolivia and Mozambique.
 Levin CE, Steele M, Atherly D, et al
Sex Transm Dis. 2007 Jul;34(7 Suppl):S47-54.
Abstract
 
Maternal and congenital syphilis in two Mexican hospitals: evaluation of a rapid diagnostic test
Hernández-Trejo M, Hernández-Prado B, Uribe-Salas F, et al
Rev Invest Clin. 2006 Mar-Apr;58(2):119-25
 Abstract
 
Diagnostic tools for preventing and managing maternal and congenital syphilis: an overview.
Peeling RW, Ye H.
Bull World Health Organ. 2004 Jun;82(6):439-46.
 Abstract
 
Evaluation of a Treponema pallidum-specific IgM enzyme immunoassay and Treponema
pallidum western blot antibody detection in the diagnosis of maternal and congenital syphilis.
Rawstron SA, Mehta S, Bromberg K. et al
Sex Transm Dis. 2004 Feb;31(2):123-6.
 Abstract

An evaluation of on-site testing for syphilis.
 Patel A, Moodley D, Moodley J.
 Trop Doct 2001 Apr;31(2):79-82
 Abstract
 
  Recognizing and treating syphilis in pregnancy
Larkin JA, Lit L, Toney J, Haley JA
Medscape Womens Health 1998 Jan;3(1):5  
Abstract
 
     Conference Reports, Abstracts, and Posters
 
  Comparison of the Diagnostic Accuracy of a Rapid Immunochromatographic Test and
the Rapid Plasma Reagin Test for Antenatal Syphilis Screening in Mozambique
 P Montoya, PE Brentlinger,  F Floriano, S Gloyd
 (134 APHA Annual Meeting)
 Abstract
Treatment
 

          Journal Papers, Abstracts, and Commentaries

 
Occurrence of congenital syphilis after maternal treatment with azithromycin during pregnancy.
 Zhou P, Qian Y, Xu J, et al  
Sex Transm Dis. 2007 Jul;34(7):472-4.
 Abstract   
 
FULL TEXT ARTICLE
Detection of Treponema pallidum subsp. pallidum from skin lesions, serum, and cerebrospinal
fluid in an infant with congenital syphilis after clindamycin treatment of the mother during
pregnancy.
Woznicová V, Smajs D, Wechsler D, et al
J Clin Microbiol. 2007 Feb;45(2):659-61
 Paper

Treatment of syphilis in pregnancy and prevention of congenital syphilis.
Wendel GD Jr, Sheffield JS, Hollier LM, 
Clin Infect Dis 2002 Oct 15;35(Suppl 2):S200-9
 Abstract   

Central nervous system infection in congenital syphilis.
 Michelow IC, Wendel GD Jr, Norgard MV, et al
N Engl J Med 2002 Jun 6;346(23):1792-8
 Abstract 
 
Congenital syphilis after maternal treatment for syphilis during pregnancy.  
 Sheffield JS, Sanchez PJ, Morris G, et al.
 Am J Obstet Gynecol 2002 Mar;186(3):569-73
 Abstract 
   
Pulmonary abscesses in congenital syphilis.
Bell C, Taxy J.
Arch Pathol Lab Med 2002 Apr;126(4):484-6
Abstract 
 
Antibiotics for syphilis diagnosed during pregnancy.
Walker GJ  
 Cochrane Database Syst Rev 2001;3:CD001143
 Abstract
 
Recognizing and treating syphilis in pregnancy
Larkin JA, Lit L, Toney J, Haley JA
Medscape Womens Health 1998 Jan;3(1):5  
Abstract
 
Syphilis in pregnancy.
 Genc M, Ledger WJ
 Sex Transm Infect 2000 Apr;76(2):73-9
 Abstract
 
Outcome Studies    
 
     Journal Papers, Abstracts, and Commentaries
 
  Syphilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancy.
 Watson-Jones D, Changalucha J, Gumodoka B, et al.
J Infect Dis 2002 Oct 1;186(7):940-7
 Abstract

Syphilis in Pregnancy in Tanzania. II. The Effectiveness of Antenatal Syphilis
Screening and Single-Dose Benzathine Penicillin Treatment for the Prevention of
Adverse Pregnancy Outcomes.
Watson-Jones D, Gumodoka B, Weiss H, et al.
Infect Dis 2002 Oct 1;186(7):948-57
 Abstract

  
Case Reports/Studies/Literature Reviews
 
     Journal Papers, Abstracts, and Commentaries
 
 
Early diffuse alopecia in a neonate with congenital syphilis.
Reddy S, Bushore D, Levy A, Skinner RB.
Pediatr Dermatol. 2006 Nov-Dec;23(6):564-6.
Abstract
 
Early congenital syphilis and erythema multiforme-like bullous targetoid lesions in a
1-day-oldnewborn: detection of Treponema pallidum genomic DNA from the targetoid
plaque using nested polymerase chain reaction.
Wu CC, Tsai CN, Wong WR, et al
J Am Acad Dermatol. 2006 Aug;55(2 Suppl):S11-5
 Abstract
 
Congenital syphilis.
Lugo A, Sanchez S, Sanchez JL.
Pediatr Dermatol. 2006 Mar-Apr;23(2):121-3
 Abstract
 
Congenital syphilis: beta2-microglobulin in cerebrospinal fluid and diagnosis of
neurosyphilis in an affected newborn.
Tagarro A, García-Alix A, Alarcón Am et al
 J Perinat Med. 2005;33(1):79-82.
 Abstract
 
Ganglioneuroma in a newborn with early inborn syphilis
Rastol'tsev KV
Arkh Patol. 2005 Jan-Feb;67(1):42-4
 Abstract

Congenital syphilis: unique clinical presentation in three preterm newborns.
 Filippi L, Serafini L, Dani C ,et al
 J Perinat Med. 2004;32(1):90-4.
 Abstract

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