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WOMEN AND HIV RESOURCE CENTER
  Maternal HIV Transmission
Risks
General Reports
Maternal Immunological Responses
 Viral Dynamics
 Viral Load
 HIV Shedding in Genital Tract
 Obstetrical Risks
 Breastfeeding Risks
 

 
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Last Update:  November 07, 2008
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General/Miscellaneous Reports
       

            Journal Papers, Abstracts, and Commentaries

 
The role of transplacental microtransfusions of maternal lymphocytes in HIV transmission to newborns.
Biggar RJ, Lee TH, Wen L, et al 
AIDS. 2008 Nov 12;22(17):2251-6.
 Abstract
 
Perinatal transmission of HIV
Gardella B, Preti E, Zanchi S, et al  
Minerva Ginecol. 2007 Apr;59(2):139-49
 Abstract
 
Herpes Simplex Virus Type 2 and Risk of Intrapartum Human Immunodeficiency Virus
Transmission
 Drake AL, John-Stewart GC, Wald A, et al 
Obstet Gynecol. 2007 Feb;109(2):403-409
 Abstract
 
Increased Risk of Intrauterine Transmission of HIV-1 Associated With Granulocyte
Elastase in Endocervical Mucus.
Kaseba-Sata C, Kasolo F, Ichiyama K, et al 
J Acquir Immune Defic Syndr. 2006 Feb 1;41(2):249-251.
 Abstract

Risk Factors for In Utero and Intrapartum Transmission of HIV.
Magder LS, Mofenson L, Paul ME, et al
J Acquir Immune Defic Syndr. 2005 Jan 1;38(1):87-95.
 Abstract
 
          Conference Reports, Abstracts, and Posters
 
 
Impact of vaginal microbes on postpartum infectious morbidity among HIV infected
and uninfected women
Sebitloane M, Moodley J
 (4th IAS Conference)
 Abstract

Role of CCR5 Promoter and CX3CR1 Polymorphisms in Mother-to-Child
Transmission of HIV-1 in African Children
 K Singh , M Hughes, J Chen, et al
(12 CROI)
 Abstract

Perinatal Transmission of HIV-1 va Amniotic Fluid, Vaginal Secretions, and Blood:
A Molecular Analysis
R Dickover , K Nielsen  , K Yusim, et al
(12 CROI)
 Abstract
 
Is Maternal Syphilis Infection a Risk Factor for Mother-to-Child Transmission of HIV?
V Mwpasa  , J Kwiek , S Rogerson ,  et al
(12 CROI)
 Abstract
Maternal Immunological Responses 
Cellular Responses Humoral Responses    
Cellular Responses

CD4+ Cells

            Journal Papers, Abstracts, and Commentaries

  Influence of maternal CD4 levels on the predictive value of virus load over mother-to-child
transmission of human immunodeficiency virus type 1 (HIV-1). Study Group for Vertical
Transmission.
Mazza C, Ravaggi A, Rodella A, et al.
J Med Virol 1999 May;58(1):59-62 
Abstract 
   
  Maternal viral load, CD4 cell count and vertical transmission of HIV-1.
O'Shea S, Newell ML, Dunn DT, et  al. 
J Med Virol. 1998 Feb;54(2):113-7.
Abstract 
   
  Effect of maternal CD4+ cell count, acquired immunodeficiency syndrome, and viral load
on disease progression in infants with perinatally acquired human immunodeficiency virus
type 1 infection. New York City Perinatal HIV Transmission Collaborative Study Group.
Lambert G, Thea DM, Pliner V, et al.
J Pediatr 1997 Jun;130(6):890-7 
 Abstract
   
  Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection.
Mellors JW, Munoz A, Giorgi JV, et al.
Ann Intern Med 1997 Jun 15;126(12):946-54 
Abstract

CD8+ Cells

        Journal Papers, Abstracts, and Commentaries

  Maternal and infant factors predicting disease progression inhuman immunodeficiency
virus type 1-infected infants. Women and Infants Transmission Study Group.
Rich KC, Fowler MG, Mofenson LM, et al
 Pediatrics 2000 Jan;105(1):e8 
Abstract
   
  Prospective study of CD8+ lymphocyte activation in relation to viral load in HIV-infected
patients with > or = 400 CD4+ lymphocytes per microliter.
Bouscarat F, Levacher M, Dazza MC,et al,
 AIDS Res Hum Retroviruses 1999 Nov 1;15(16):1419-25
Abstract
   
  Allo-immunization elicits CD8+ T cell-derived chemokines, HIV suppressor factors and
resistance to HIV infection in women.
Wang Y, Tao L, Mitchell E, et al
 Nat Med 1999 Sep;5(9):1004-9
Abstract
   
  Decreased CD8 cell-mediated viral suppression and other immunologic characteristics of
women who transmit human immunodeficiency virus to their infants.
Plaeger S, Bermudez S, Mikyas Y, et al
J Infect Dis 1999 Jun;179(6):1388-94 
Abstract
   
  CD8+ lymphocytes in pregnancy and HIV infection: characterization of CD8+ subpopulations
and CD8+ noncytotoxic antiviral activity.
Rich KC, Siegel JN, Jennings C, et al,
AIDS Res Hum Retroviruses 1999 May ;15(7):665-70 
Abstract 
   
  Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study.
Tuomala RE, Kalish LA, Zorilla C, et al
Obstet Gynecol 1997Jun;89(6):967-74 
Abstract
   
  Prospective study of CD8+ lymphocyte activation in relation to viral load in HIV-infected
patients with > or = 400 CD4+ lymphocytes per microliter.
Bouscarat F, Levacher M, Dazza MC, et al,
AIDS Res Hum Retroviruses 1999 Nov 1;15(16):1419-25
Abstract

Humoral Responses

        Journal Papers, Abstracts, and Commentaries

  Maternal humoral factors associated with perinatal human immunodeficiency virus
type-1 transmission in a cohort from Kigali,
Tranchat C, Van de Perre P, et al
 J Infect 1999 Nov;39(3):213-20 
Abstract
   
  Role of maternal humoral immunity in vertical transmission of HIV-1 subtype E in
Thailand.
Louisirirotchanakul S, Beddows S, Cheingsong R, et al
J Acquir Immune Defic Syndr 1999 Aug
Abstract
   
  Apparent enhancement of perinatal transmission of human immunodeficiency virus
type 1 by high maternal anti-gp160 antibody titer.
 Pancino G, Leste-Lasserre T, Burgard M, et al
J Infect Dis 1998 Jun;177(6):1737-41  
Abstract
 
Viral Dynamics
 

          Journal Papers, Abstracts, and Commentaries

 

Influence of human immunodeficiency virus type 1 subtype on mother-to-child transmission.
Tapia N, Franco S, Puig-Basagoiti F, Menendez C   
J Gen Virol 2003 Mar;84(Pt 3):607-13
 Abstract

 
Viral Load
 
        Journal Papers, Abstracts, and Commentaries|
 
  Perinatal Transmission of Human Immunodeficiency Virus Type 1 by Pregnant Women
with RNA Virus Loads <1000 Copies/mL.
Ioannidis JP, Abrams EJ, Ammann A, et al
J Infect Dis 2001 Jan;183(4):539-545
Abstract
   
  Maternal viral load and vertical transmission of HIV-1: an important factor but not the only
one.
The European Collaborative Study.
AIDS 1999 Jul 30;13(11):1377-85  
Abstract
   
  Maternal virus load and perinatal human immunodeficiency virus type 1 subtype E
transmission, Thailand. Bangkok Collaborative Perinatal HIVTransmission Study Group.
Shaffer N, Roongpisuthipong A, Siriwasin W, et al  
J Infect Dis 1999 Mar;179(3):590-9  
Abstract
   
  Maternal viral load and timing of mother-to-child HIV transmission, Bangkok, Thailand.
Bangkok Collaborative Perinatal HIV Transmission Study Group.
Mock PA, Shaffer N, Bhadrakom C,  et al
 AIDS 1999 Feb 25;13(3):407-14
Abstract
   
  Maternal viral and gestational risk factors in vertical transmission of HIV-1 infection
Greco P, Vimercati A, Fiore JR, et al
Minerva Ginecol 1998 Nov 0(11):449-54
Abstract
   
  Intrapartum mucosal exposure to human immunodeficiency virus type 1 (HIV-1) of infants
born to HIV-1-infected mothers correlates with maternal plasma virus burden.
Ait-Khaled M, Lyall EG, Stainsby C, et al
J Infect Dis 1998 Apr;177(4):1097-100 
Abstract
   
  Maternal HIV-1 viral load and vertical transmission of infection: the Ariel Project for the
prevention of HIV transmission from mother to infant.
 Cao Y, Krogstad P, Korber BT, Koup RA, et al
J Nat Med 1997 May;3(5):549-52 
Abstract
   
  Viral load and disease progression in infants infected with human immunodeficiency virus
type 1. Women and Infants Transmission Group
Shearer WT, Quinn TC, LaRussa P, et al
 N Engl J Med 1997 May 8;336(19):1337-42
Abstract
   
  Maternal viral load, CD4 cell count and vertical transmission of HIV-1.
O'Shea S, Newell ML, Dunn DT, et al
 J Med Virol 1998 Feb;54(2):113-7 
Abstract
   
  Maternal viral load, CD4 cell count and vertical transmission of HIV-1.
O'Shea S, Newell ML, Dunn DT, et al
 J Med Virol 1998 Feb;54(2):113-7 
Abstract
   
  The effect of maternal viral load on the risk of perinatal transmission of HIV-1. New York
City Perinatal HIV Transmission Collaborative Study Group.
Thea DM, Steketee RW, Pliner V, et al
AIDS 1997 Mar 15;11(4):437-44
Abstract
   
  Maternal viral load, zidovudine treatment, and the risk of transmission of human
immunodeficiency virus type 1 from mother to infant.
Sperling RS, Shapiro DE, Coombs RW, et al.
N Engl J Med 1996;335:1621-1629.  
Abstract
   
  Influence of other maternal variables on the relationship between maternal virus load and
mother-to-infant transmission of human immunodeficiency virus type 1.
Burns DN, Landesman S, Wright DJ, et al.,
 J Infect Dis, 1997. 175: p. 1206-1210. 
Abstract
   
  Vertical HIV-1 transmission correlates with a high maternal viral load at delivery 
Coll O, Hernandez M, Boucher CAB, et al
J Acquir Immune Defic Syndr Hum Retrovirol, 1997. 14: p. 26-30. 
Abstract
 
HIV Shedding in Genital Tract
 

          Journal Papers, Abstracts, and Commentaries

  Effect of menstrual cycle on HIV-1 levels in the peripheral blood and genital tract.
WHS 001 Study Team.
Reichelderfer PS, Coombs RW, Wright DJ, et al
AIDS 2000 Sep 29;14(14):2101-7  
Abstract
   
  Frequent detection of HIV-1 RNA but low rates of HIV-1 isolation in cervicovaginal
secretions from infected women.
Saracino A, Di Stefano M, Fiore JR, et al  
New Microbiol 2000 Jan;23(1):79-83  
Abstract
   
  Genital HIV shedding in women.
Iversen AK
Aids Patient Care STDS 1999 Dec;13(12):695-701  
Abstract
   
  Genital tract human immunodeficiency virus type 1 (HIV-1) shedding and inflammation
and HIV-1 env diversity in perinatal HIV-1 transmission.
Panther LA, Tucker L, Xu C, et al
J Infect Dis 2000 Feb;181(2):555-63  
Abstract
   
  Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells
throughout the menstrual cycle.
Mostad SB, Jackson S, Overbaugh J, Ret al
J Infect Dis 1998 Oct;178(4):983-91
Abstract
   
  Prevalence and correlates of HIV type 1 shedding in the female genital tract
Mostad SB
AIDS Res Hum Retroviruses 1998 Apr;14 Suppl 1:S11-5  
Abstract
   
  Human immunodeficiency virus type 1 RNA shedding in the female genital tract.
Goulston C, McFarland W, Katzenstein D
J Infect Dis 1998 Apr;177(4):1100-3
Abstract
   
  Effect of menstrual cycle on HIV-1 levels in the peripheral blood and genital tract.
WHS 001 Study Team.
Reichelderfer PS, Coombs RW, Wright DJ, et al
AIDS 2000 Sep 29;14(14):2101-7  
Abstract
   
  Frequent detection of HIV-1 RNA but low rates of HIV-1 isolation in cervicovaginal secretions
from infected women.
Saracino A, Di Stefano M, Fiore JR, et al  
New Microbiol 2000 Jan;23(1):79-83  
Abstract
   
  Genital HIV shedding in women.
Iversen AK
Aids Patient Care STDS 1999 Dec;13(12):695-701  
Abstract
   
  Genital tract human immunodeficiency virus type 1 (HIV-1) shedding and inflammation and
HIV-1 env diversity in perinatal HIV-1 transmission.
Panther LA, Tucker L, Xu C, et al
J Infect Dis 2000 Feb;181(2):555-63  
Abstract
   
  Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells
throughout the menstrual cycle.
Mostad SB, Jackson S, Overbaugh J,et al
J Infect Dis 1998 Oct;178(4):983-91
Abstract
 

 

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