MEDICAL ADVOCATES
WOMEN AND HIV RESOURCE CENTER
  Maternal HIV Transmission
Risks

General Reports
Amniocentesis
Maternal Immunological Responses
Viral Dynamics
Viral Load
HIV Shedding in Genital Tract
Obstetrical Risks

Breastfeeding Risks
 


 

HIV Pregnancy Main Page Women Main Page  

Last Update:  February 28, 2015
 Documents identified with this icon are in Portable Document Format (PDF) and require the Adobe Acrobat Reader

General/Miscellaneous Reports
       

            Journal Papers, Abstracts, and Commentaries

 
Risk factors of hiv-1 vertical transmission (vt) and the influence of antiretroviral therapy (art) in pregnancy outcome.
Barral MF, Oliveira GR, Lobato RC,  et al
Rev Inst Med Trop Sao Paulo
. 2014 Mar-Apr;56(2):133-8.
Abstract

FULL-TEXT PDF ARTICLE
Role of the Placenta in Adverse Perinatal Outcomes among HIV-1 Seropositive Women.
Ackerman Iv W, J Kwiek J.
J Nippon Med Sch
. 2013;80(2):90-4
Paper

Virologic and Host Risk Factors for Mother-to-Child Transmission of HIV.
Selvaraj S, Paintsil E.
Curr HIV Res. 2013 Feb 21
Abstract

FULL-TEXT ARTICLE
Peripartum cardiomyopathy coexistent with human immunodeficiency virus: a substantial obstetric jeopardy.
Mandal D, Dattaray C, Dutta M, Sarkar G, Sinha P.
Heart Views. 2013 Jan;14(1):26-8
Paper

Bolstering the Evidence Base for Integrating Abortion and HIV Care: A Literature Review.
Manski R, Dennis A, Blanchard K, et al.
AIDS Res Treat. 2012;2012:802389.
Abstract

Maternal HIV Infection and Vertical Transmission of Pathogenic Bacteria.
Cutland CL, Schrag SJ, Zell ER,  et al
Pediatrics
. 2012 Aug 6.
Abstract

Premasticating Food for Weaning African Infants: A Possible Vehicle for Transmission of HIV.
Maritz ER, Kidd M, Cotton MF.
Pediatrics
. 2011 Aug 28
Abstract

Different  Regions of HIV-1 Subtype C ENV are Associated with Placental Localization and in Utero
Mother-to-Child Transmission
Kumar SB, Handelman SK, Voronkin I, et al
J Virol
. 2011 May 4.
Abstract

A new unique recombinant HIV-1 isolated from child born from HIV-infected mother.
Eremin VF, Gasich EL, Sasinovich SV.
AIDS Res Hum Retroviruses
.
2011 May 3.
Abstract

Advances in basic science understanding of mother-to-child HIV-1 transmission.
Walter J, Kuhn L, Aldrovandi GM. 
Curr Opin HIV AIDS
. 2008 Mar;3(2):146-50.
Abstract

A WEEK-IN-REVIEW FEATURED REPORT
Interventions for preventing late postnatal mother-to-child transmission of HIV.
Horvath T, Madi BC, Iuppa IM, et al
Cochrane Database Syst Rev
. 2009 Jan 21;(1):CD006734.
Abstract
 

The role of transplacental microtransfusions of maternal lymphocytes in HIV transmission to newborns.
Biggar RJ, Lee TH, Wen L, et al
 
AIDS.
2008 Nov 12;22(17):2251-6.
Abstract
 
Perinatal transmission of HIV
Gardella B, Preti E, Zanchi S, et al  
Minerva Ginecol.
2007 Apr;59(2):139-49
Abstract

 
Herpes Simplex Virus Type 2 and Risk of Intrapartum Human Immunodeficiency Virus
Transmission

Drake AL, John-Stewart GC, Wald A, et al 
Obstet Gynecol. 2007 Feb;109(2):403-409
Abstract

 
Increased Risk of Intrauterine Transmission of HIV-1 Associated With Granulocyte
Elastase in Endocervical Mucus.
Kaseba-Sata C, Kasolo F, Ichiyama K, et al 

J Acquir Immune Defic Syndr.
2006 Feb 1;41(2):249-251.
Abstract

Risk Factors for In Utero and Intrapartum Transmission of HIV.
Magder LS, Mofenson L, Paul ME, et al

J Acquir Immune Defic Synd
r. 2005 Jan 1;38(1):87-95.
Abstract
 

          Conference Reports, Abstracts, and Posters
 
 
Impact of vaginal microbes on postpartum infectious morbidity among HIV infected
and uninfected women
Sebitloane M, Moodley J
(4th IAS Conference)
Abstract

Amniocentesis
 

          Journal Papers, Abstracts, and Commentaries

 

A WEEK-IN-REVIEW FEATURED REPORT
Amniocentesis and viral risk (hepatitis B, C virus and HIV).
Ducarme G, Ceccaldi PF, Bernuau J, Luton D.

J Gynecol Obstet Biol Reprod (Paris)
. 2009 Aug 11
Abstract

 

Maternal Immunological Responses 
Cellular Responses Humoral Responses    

Cellular Responses

CD4+ Cells

            Journal Papers, Abstracts, and Commentaries

  Influence of maternal CD4 levels on the predictive value of virus load over mother-to-child
transmission of human immunodeficiency virus type 1 (HIV-1). Study Group for Vertical
Transmission
.
Mazza C, Ravaggi A, Rodella A, et al.
J Med Virol 1999 May;58(1):59-62 

Abstract 
   
  Maternal viral load, CD4 cell count and vertical transmission of HIV-1.
O'Shea S, Newell ML, Dunn DT,
et  al. 
J Med Virol. 1998 Feb;54(2):113-7.

Abstract
 
   
  Effect of maternal CD4+ cell count, acquired immunodeficiency syndrome, and viral load
on disease progression in infants with perinatally acquired human immunodeficiency virus
type 1 infection. New York City Perinatal HIV Transmission Collaborative Study Group
.
Lambert G, Thea DM, Pliner V, et al.
J Pediatr
1997 Jun;130(6):890-7 
Abstract
   
  Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection.
Mellors JW, Munoz A, Giorgi JV, et al.
Ann Intern Med 1997 Jun 15;126(12):946-54
 
Abstract

CD8+ Cells

        Journal Papers, Abstracts, and Commentaries

  Maternal and infant factors predicting disease progression inhuman immunodeficiency
virus type 1-infected infants. Women and Infants Transmission Study Group
.
Rich KC, Fowler MG, Mofenson LM, et al
Pediatrics 2000 Jan;105(1):e8
 
Abstract
   
  Prospective study of CD8+ lymphocyte activation in relation to viral load in HIV-infected
patients with > or = 400 CD4+ lymphocytes per microliter.
Bouscarat F, Levacher M, Dazza MC,et al,
AIDS Res Hum Retroviruses 1999 Nov 1;15(16):1419-25

Abstract
   
  Allo-immunization elicits CD8+ T cell-derived chemokines, HIV suppressor factors and
resistance to HIV infection in women.
Wang Y, Tao L, Mitchell E, et al
Nat Med 1999 Sep;5(9):1004-9
Abstract
   
  Decreased CD8 cell-mediated viral suppression and other immunologic characteristics of
women who transmit human immunodeficiency virus to their infants
.
Plaeger S, Bermudez S, Mikyas Y, et al

J
Infect Dis 1999 Jun;179(6):1388-94 

Abstract
   
  CD8+ lymphocytes in pregnancy and HIV infection: characterization of CD8+ subpopulations
and CD8+ noncytotoxic antiviral activity.

Rich KC, Siegel JN, Jennings C, et al,

AIDS Res Hum Retroviruses 1999 May ;15(7):665-70
 
Abstract 
   
  Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study.
Tuomala RE, Kalish LA, Zorilla C, et al
Obstet Gynecol 1997Jun;89(6):967-74
 
Abstract
   
  Prospective study of CD8+ lymphocyte activation in relation to viral load in HIV-infected
patients with > or = 400 CD4+ lymphocytes per microliter.
Bouscarat F, Levacher M, Dazza MC, et al,
A
IDS Res Hum Retroviruses
1999 Nov 1;15(16):1419-25

Abstract

Humoral Responses

        Journal Papers, Abstracts, and Commentaries

  Maternal humoral factors associated with perinatal human immunodeficiency virus
type-1 transmission in a cohort from Kigali,

Tranchat C, Van de Perre P, et al
J Infect 1999 Nov;39(3):213-20
 
Abstract
   
  Role of maternal humoral immunity in vertical transmission of HIV-1 subtype E in
Thailand.
Louisirirotchanakul S, Beddows S, Cheingsong R, et al
J Acquir Immune Defic Syndr 1999 Aug
Abstract
   
  Apparent enhancement of perinatal transmission of human immunodeficiency virus
type 1 by high maternal anti-gp160 antibody titer
.
Pancino G, Leste-Lasserre T, Burgard M, et al
J Infect Dis 1998
Jun;177(6):1737-41  
Abstract
 

Viral Dynamics
 

          Journal Papers, Abstracts, and Commentaries

 

Influence of human immunodeficiency virus type 1 subtype on mother-to-child transmission.
Tapia N, Franco S, Puig-Basagoiti F, Menendez C 
 
J Gen Virol
2003 Mar;84(Pt 3):607-13
Abstract

 

Viral Load
 

        Journal Papers, Abstracts, and Commentaries|
 
  Perinatal Transmission of Human Immunodeficiency Virus Type 1 by Pregnant Women
with RNA Virus Loads <1000 Copies/mL
.
Ioannidis JP, Abrams EJ, Ammann A,
et al
J Infect Dis
2001 Jan;183(4):539-545

Abstract
   
  Maternal viral load and vertical transmission of HIV-1: an important factor but not the only
one
.
The European Collaborative Study.
AIDS
1999 Jul 30;13(11):1377-85
 
Abstract
   
  Maternal virus load and perinatal human immunodeficiency virus type 1 subtype E
transmission, Thailand. Bangkok Collaborative Perinatal HIVTransmission Study Group
.
Shaffer N, Roongpisuthipong A, Siriwasin W,
et al  
J Infect Dis
1999 Mar;179(3):590-9  
Abstract
   
  Maternal viral load and timing of mother-to-child HIV transmission, Bangkok, Thailand.
Bangkok Collaborative Perinatal HIV Transmission Study Group
.
Mock PA, Shaffer N, Bhadrakom C, 
et al
AIDS 1999 Feb 25;13(3):407-14
Abstract
   
  Maternal viral and gestational risk factors in vertical transmission of HIV-1 infection
Greco P, Vimercati A, Fiore JR,
et al
Minerva Ginecol 1998 Nov 0(11):449-54

Abstract
   
  Intrapartum mucosal exposure to human immunodeficiency virus type 1 (HIV-1) of infants
born to HIV-1-infected mothers correlates with maternal plasma virus burden
.
Ait-Khaled M, Lyall EG, Stainsby C,
et al
J Infect Dis
1998 Apr;177(4):1097-100 
Abstract
   
  Maternal HIV-1 viral load and vertical transmission of infection: the Ariel Project for the
prevention of HIV transmission from mother to infant
.
Cao Y, Krogstad P, Korber BT, Koup RA,
et al
J
Nat Med
1997 May;3(5):549-52 
Abstract
   
  Viral load and disease progression in infants infected with human immunodeficiency virus
type 1.
Women and Infants Transmission Group

Shearer WT, Quinn TC, LaRussa P, et al

N Engl J Med
1997 May 8;336(19):1337-42
Abstract
   
  Maternal viral load, CD4 cell count and vertical transmission of HIV-1.
O'Shea S, Newell ML, Dunn DT,
et al
J Med Virol 1998 Feb;54(2):113-7 
Abstract
   
  Maternal viral load, CD4 cell count and vertical transmission of HIV-1.
O'Shea S, Newell ML, Dunn DT,
et al
J Med Virol 1998 Feb;54(2):113-7 
Abstract
   
  The effect of maternal viral load on the risk of perinatal transmission of HIV-1. New York
City Perinatal HIV Transmission Collaborative Study Group
.
Thea DM, Steketee RW, Pliner V,
et al
AIDS 1997 Mar 15;11(4):437-44
Abstract
   
  Maternal viral load, zidovudine treatment, and the risk of transmission of human
immunodeficiency virus type 1 from mother to infant
.
Sperling RS, Shapiro DE, Coombs RW, et al.
N Engl J Med
1996;335:1621-1629.
 
Abstract
   
  Influence of other maternal variables on the relationship between maternal virus load and
mother-to-infant transmission of human immunodeficiency virus type 1
.
Burns DN, Landesman S, Wright DJ, et al.,
 
J Infect Dis, 1997. 175: p. 1206-1210. 
Abstract
   
  Vertical HIV-1 transmission correlates with a high maternal viral load at delivery 
Coll O, Hernandez M, Boucher CAB, et al

J Acquir Immune Defic Syndr Hum Retrovirol,
1997. 14: p. 26-30. 
Abstract
 

HIV Shedding in Genital Tract
 

          Journal Papers, Abstracts, and Commentaries

  Effect of menstrual cycle on HIV-1 levels in the peripheral blood and genital tract.
WHS 001 Study Team
.
Reichelderfer PS, Coombs RW, Wright DJ, et al
AIDS
2000 Sep 29;14(14):2101-7  
Abstract
   
  Frequent detection of HIV-1 RNA but low rates of HIV-1 isolation in cervicovaginal
secretions from infected women
.
Saracino A, Di Stefano M, Fiore JR, et al  
New Microbiol
2000 Jan;23(1):79-83  
Abstract
   
  Genital HIV shedding in women.
Iversen AK
Aids Patient Care STDS 1999 Dec;13(12):695-701  
Abstract
   
  Genital tract human immunodeficiency virus type 1 (HIV-1) shedding and inflammation
and HIV-1 env diversity in perinatal HIV-1 transmission.
Panther LA, Tucker L, Xu C, et al
J Infect Dis
2000 Feb;181(2):555-63  
Abstract
   
  Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells
throughout the menstrual cycle.

Mostad SB, Jackson S, Overbaugh J, Ret al
J Infect Dis 1998 Oct;178(4):983-91

Abstract
   
  Prevalence and correlates of HIV type 1 shedding in the female genital tract
Mostad SB

AIDS Res Hum Retroviruses 1998 Apr;14 Suppl 1:S11-5
 
Abstract
   
  Human immunodeficiency virus type 1 RNA shedding in the female genital tract.
Goulston C, McFarland W, Katzenstein D

J Infect Dis
1998 Apr;177(4):1100-3
Abstract
   
  Effect of menstrual cycle on HIV-1 levels in the peripheral blood and genital tract.
WHS 001 Study Team
.
Reichelderfer PS, Coombs RW, Wright DJ, et al

AIDS
2000 Sep 29;14(14):2101-7
 
Abstract
   
  Frequent detection of HIV-1 RNA but low rates of HIV-1 isolation in cervicovaginal secretions
from infected women
.
Saracino A, Di Stefano M, Fiore JR, et al  

New Microbiol
2000 Jan;23(1):79-83
 
Abstract
   
  Genital HIV shedding in women.
Iversen AK
Aids Patient Care STDS 1999 Dec;13(12):695-701
 
Abstract
   
  Genital tract human immunodeficiency virus type 1 (HIV-1) shedding and inflammation and
HIV-1 env diversity in perinatal HIV-1 transmission.
Panther LA, Tucker L, Xu C, et al
J Infect Dis
2000 Feb;181(2):555-63  
Abstract
   
  Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells
throughout the menstrual cycle.

Mostad SB, Jackson S, Overbaugh J,et al
J
Infect Dis 1998 Oct;178(4):983-91

Abstract
 

 


HIV Pregnancy Main Page Women Main Page  

  Maternal HIV Transmission Risks