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CMV Infection

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Perinatal Disease Index Main New and Noteworthy Home Page

Last Update:  April 12, 2012 
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New and Noteworthy
       
April 2013
 
General Reports
 

        Journal Papers, Abstracts, and Commentaries

 
Human cytomegalovirus infection is detected frequently in stillbirths and is associated
with fetal thrombotic vasculopathy.
 Iwasenko JM, Howard J, Arbuckle S,  et al
J Infect Dis. 2011 Jun;203(11):1526-33.
 Abstract

Decreased risk of congenital cytomegalovirus infection in children born to
HIV-1-infected mothers in the era of highly active antiretroviral therapy.
Guibert G, Warszawski J, Le Chenadec J,  et al
Clin Infect Dis. 2009 Jun 1;48(11):1516-25
 Abstract

Higher risk of cytomegalovirus reactivation in human immunodeficiency virus-1-infected patients
homozygous for MICA5.1.
Moenkemeyer M, Heiken H, Schmidt RE, Witte T. 
Hum Immunol. 2009 Mar;70(3):175-8
 Abstract
 
Postnatal CMV - innocent bystander or hidden problem?
 Luck SE, Sharland M.  
Arch Dis Child Fetal Neonatal Ed. 2008 Oct 6.
 Abstract
 
Congenital cytomegalovirus infection.
 Gomila A, Rivas N, López EL. 
An Pediatr (Barc). 2008 Oct;69(4):311-5.
 Abstract
 
Maternal Epstein-Barr virus and cytomegalovirus infections and risk of testicular cancer in the offspring:
a nested case-control study.
Holl K, Surcel HM, Koskela P, et al
 APMIS. 2008 Sep;116(9):816-22.
 Abstract
 
Cytomegalovirus (CMV) congenital infection.
Benoist G, Jacquemard F, Leruez-Ville M, Ville Y.
Gynecol Obstet Fertil. 2008 Mar;36(3):248-60.
Abstract
 
FULL TEXT PDF ARTICLE
 Cytomegalovirus induces abnormal chondrogenesis and osteogenesis during embryonic
mandibular development.
 Jaskoll T, Abichaker G, Sedghizadeh PP, et al
BMC Dev Biol. 2008 Mar 27;8(1):33
Paper
 
Cytomegalovirus infection in early infancy: risk of induction and progression of autoimmunity
associated with type 1 diabetes.
Aarnisalo J, Veijola R, Vainionpää R,et al
 Diabetologia. 2008 Feb 16
 Abstract
 
Congenital cytomegalovirus (CMV) infection as a cause of permanent bilateral hearing loss:
A quantitative assessment.
Grosse SD, Ross DS, Dollard SC. et al  
J Clin Virol. 2007 Oct 22;
Abstract
 
Cytomegalovirus, breast feeding and prematurity
Ha˙s S.
 Arch Pediatr. 2007 Sep;14 Suppl 1:S2-4.
Abstract
 
Congenital cytomegalovirus infection: a cause of renal dysplasia?
 Chan M, Hecht JL, Boyd T, Rosen S. 
Pediatr Dev Pathol. 2007 Jul-Aug;10(4):300-4.
Abstract
 
New estimates of the prevalence of neurological and sensory sequelae and mortality associated
with congenital cytomegalovirus infection.
 Dollard SC, Grosse SD, Ross DS, et al  
Rev Med Virol. 2007 Jun 1;
 Abstract
 
Congenital cytomegalovirus infection: A cause of renal dysplasia?
Chan M, Hecht J, Boyd T, Rosen S.
Pediatr Dev Pathol. 2007 Mar 22;:1
Abstract
 
Congenital cytomegalovirus infections.
 Malm G, Engman ML 
Semin Fetal Neonatal Med. 2007 Mar 2;
 Abstract
 
Development of Human Cytomegalovirus-Specific T Cell Immunity during Primary Infection of
Pregnant Women and Its Correlation with Virus Transmission to the Fetus.
 Lilleri D, Fornara C, Furione M, et al  
 J Infect Dis. 2007 Apr 1;195(7):1062-70.
 Abstract
 
Immunological response to cytomegalovirus in congenitally infected neonates.
 Hassan J, Dooley S, Hall W, et al  
 Clin Exp Immunol. 2007 Mar;147(3):465-71.
 Abstract
 
Placental enlargement in women with primary maternal cytomegalovirus infection is
associated with fetal and neonatal disease.
 La Torre R, Nigro G, Mazzocco M, et al  
 Clin Infect Dis. 2006 Oct 15;43(8):994-1000.
Abstract
 
Risk factors for congenital cytomegalovirus infection in the offspring of young women:
exposure to young children and recent onset of sexual activity.
Fowler KB, Pass RF.  
Pediatrics. 2006 Aug;118(2):e286-92.
Abstract
 
The congenital cytomegalovirus infection: virus-host interaction for defense and transmission.
Halwachs-Baumann G
Curr Pharm Biotechnol. 2006 Aug;7(4):303-12.
 Abstract
 
Neonatal cytomegalovirus blood load and risk of sequelae in symptomatic and asymptomatic
congenitally infected newborns.
 Lanari M, Lazzarotto T, Venturi V, et al  
Pediatrics. 2006 Jan;117(1):e76-83.
 Abstract
 
FULL-TEXT PDF ARTICLE
 Washing our hands of the congenital cytomegalovirus disease epidemic.
Cannon MJ, Davis KF.
BMC Public Health. 2005 Jun 20;5(1):70
PDF Paper
 
Interval between births and risk of congenital cytomegalovirus infection.
Fowler KB, Stagno S, Pass RF. et al 
Clin Infect Dis. 2004 Apr 1;38(7):1038-9.
 Abstract
 
Severe fetal cytomegalovirus infection associated with cerebellar hemorrhage.
Ortiz JU, Ostermayer E, Fischer T  
Ultrasound Obstet Gynecol. 2004 Apr;23(4):402-6.
 Abstract
 
CMV infection: when should medical termination of pregnancy be discussed?
 Benachi A, Picone O, Dumez Y.
Gynecol Obstet Fertil. 2003 Jun;31(6):521-4.
 Abstract
Transmission
 

        Journal Papers, Abstracts, and Commentaries      
          
 
Maternal Human Immunodeficiency Virus Infection and Congenital Transmission of
Cytomegalovirus.
 Duryea EL, Sánchez PJ, Sheffield JS, et al
Pediatr Infect Dis J. 2010 Apr 27.
 Abstract

Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by
neonatal Fc receptor-mediated transcytosis.
Maidji E, McDonagh S, Genbacev O, et al
Am J Pathol. 2006 Apr;168(4):1210-26.
 Abstract
 
Pilot epidemiologic study about transmission of cytomegalovirus from mother to
preterm infant by breastfeeding.
 Croly-Labourdette S, Vallet S, Gagneur A, et al  
Arch Pediatr. 2006 Apr 6;
Abstract
 
Pre- and periconceptional primary cytomegalovirus infection: risk of vertical transmission
and congenital disease.
 Daiminger A, Bader U, Enders G.
Obstet Gynecol Surv. 2005 Jul;60(7):420-2.
Abstract
Guidelines
 
        Journal Papers, Abstracts, and Commentaries
 
  Guidelines on CMV congenital infection.
 Coll O, Benoist G, Ville Y, et al
J Perinat Med. 2009 Aug 13.
Abstract
Screening
 

        Journal Papers, Abstracts, and Commentaries      
          
 
Dried blood spot real-time polymerase chain reaction assays to screen newborns for congenital
cytomegalovirus infection.
 Boppana SB, Ross SA, Novak Z, Shimamura M,
 JAMA. 2010 Apr 14;303(14):1375-82.
 Abstract

Use of Screening Dried Blood Spots for Estimation of Prevalence, Risk Factors,
and Birth Outcomes of Congenital Cytomegalovirus Infection.
 Kharrazi M, Hyde T, Young S,  et al
 J Pediatr. 2010 Apr 16.
Abstract

Newborn screening for congenital cytomegalovirus: Options for hospital-based and public health programs.
Grosse SD, Dollard S, Ross DS, Cannon M. 
J Clin Virol. 2009 Sep 25
 Abstract

Detection of congenital cytomegalovirus infection using umbilical cord blood samples in a
screening survey.
Endo T, Goto K, Ito K, Sugiura T, et al  
J Med Virol. 2009 Aug 20;81(10):1773-1776.
 Abstract

Utility of newborn screening cards for detecting CMV infection in cases of stillbirth.
Howard J, Hall B, Brennan LE, Arbuckle S,  et al
J Clin Virol. 2009 Jan 27
 Abstract
 
Neonatal screening for congenital cytomegalovirus infection and hearing loss.
Barbi M, Binda S, Caroppo S, Primache V.  
J Clin Virol. 2006 Feb;35(2):206-9
 Abstract

FULL-TEXT ARTICLE
Newborn screening for congenital infectious diseases.
Neto EC, Rubin R, Schulte J, Giugliani R.
Emerg Infect Dis 2004 Jun
 Paper
Prevention
 
    Journal Papers, Abstracts, and Commentaries    
 
 
Recent advances in the prevention and treatment of congenital cytomegalovirus infections.
Adler SP, Nigro G, Pereira L.  
Semin Perinatol. 2007 Feb;31(1):10-8.
 Abstract

Breastfeeding and Cytomegalovirus infection in preterm infants. How to reduce the risks?
Radi S, Janvresse C, Lardennois C, et al 
Arch Pediatr. 2006 Nov 20
 Abstract

The epidemiology and prevention of congenital cytomegalovirus infection and disease: activities
of the centers for disease control and prevention workgroup.
 Ross DS, Dollard SC, Victor M, et al 
J Womens Health (Larchmt). 2006 Apr;15(3):224-9.
Abstract|
Diagnosis/Diagnostics
 

    Journal Papers, Abstracts, and Commentaries    

 
Problems and challenges in the diagnosis of vertical infection with human cytomegalovirus (CMV):
Lessons from two accidental cases.
Berger A, Reitter A, Harter PN, et al  
J Clin Virol. 2011 Jun 2.
 Abstract

Brain magnetic resonance findings in symptomatic congenital cytomegalovirus infection.
 Manara R, Balao L, Baracchini C,  et al  
Pediatr Radiol. 2011 May 20.
 Abstract

Early cerebral lesions in cytomegalovirus infection: prenatal MR imaging.
Doneda C, Parazzini C, Righini A, et al
Radiology. 2010 May;255(2):613-21.
 Abstract

Evaluation of DNA extraction methods for dried blood spots in the diagnosis of congenital
cytomegalovirus infection.
 de Vries JJ, Claas EC, Kroes AC, Vossen AC.
J Clin Virol. 2009 Sep 23.
Abstract

Measurement of the sensitivity of different commercial assays in the diagnosis of CMV
infection in pregnancy.
 Gentile M, Galli C, Pagnotti P, et al 
Eur J Clin Microbiol Infect Dis. 2009 Apr 10
 Abstract

Clinical predictive value of real-time PCR quantification of human cytomegalovirus DNA in amniotic
fluid samples.
 Goegebuer T, Van Meensel B, Beuselinck K, et al
J Clin Microbiol. 2008 Dec 24
 Abstract
 
Congenital cytomegalovirus: Association between dried blood spot viral load and hearing loss.
Walter S, Atkinson C, Sharland M, et al 
Arch Dis Child Fetal Neonatal Ed. 2007 Nov 26;
 Abstract
 
Evaluation of cytomegalovirus (CMV) DNA quantification in dried blood spots: retrospective
study of CMV congenital infection.
 Vauloup-Fellous C, Ducroux A, Couloigner V, et al 
J Clin Microbiol. 2007 Nov;45(11):3804-6.
 Abstract
 
A Two-Step Strategy for Detecting Intrauterine Cytomegalovirus Infection with Clinical
Manifestations in the Mother, Fetus, and Newborn.
Kaneko M, Sameshima H, Ikenoue T, Minematsu T. 
Jpn J Infect Dis. 2006 Dec;59(6):363-366.
 Abstract
 
Detection of HCMV DNA in placenta, amniotic fluid and fetuses of seropositive women by
nested PCR.
Ziyaeyan M, Alborzi A, Abbasian A, et al 
Eur J Pediatr. 2006 Nov 3
 Abstract
 
Congenital Cytomegalovirus Infection Diagnosed by Polymerase Chain Reaction With the
Use of Preserved Umbilical Cord in Sensorineural Hearing Loss Children.
 Ogawa H, Baba Y, Suzutani T, Inoue N, et al  
 Laryngoscope. 2006 Nov;116(11):1991-1994.
Abstract
 
Diagnosis of congenital CMV infection via dried blood spots.
 Barbi M, Binda S, Caroppo S.
Rev Med Virol. 2006 Nov-Dec;16(6):385-92.
 Abstract
 
Optimisation of retrospective diagnosis of cytomegalovirus congenital infection from
dried blood spots.
Vauloup-Fellous C, Dubreuil P, Grangeot-Keros L
 Pathol Biol (Paris). 2006 Oct 4;
Abstract
 
Diagnosis of congenital CMV infection via dried blood spots.
 Barbi M, Binda S, Caroppo S. 
Rev Med Virol. 2006 Sep 27
 Abstract
 
Congenital Cytomegalovirus Infection Diagnosed by Polymerase Chain Reaction
With the Use of Preserved Umbilical Cord.
Kakizawa H, Okumura A, Suzuki Y, et al 
Pediatr Infect Dis J. 2005 Jul;24(7):653-654.
 Abstract
 
Retrospective diagnosis of congenital infection by cytomegalovirus in the case of one infant.
Lopez-Pison J, Rubio-Rubio R, Urena-Hornos T, et al  
 Rev Neurol. 2005 Jun 16-30;40(12):733-6.
 Abstract
 
A serological testing algorithm for the diagnosis of primary CMV infection in pregnant women.
Mace M, Sissoeff L, Rudent A, Grangeot-Keros L. 
Prenat Diagn. 2004 Nov 24;24(11):861-863
 Abstract
 
CMV infections of the neonate: prevalence, diagnosis, therapy
 Vochem M.
 Z Geburtshilfe Neonatol. 2003 May-Jun;207(3):114-8.
Abstract

Prenatal diagnosis of congenital cytomegalovirus infection by detection of immunoglobulin M
antibodies to the 70-kd heat shock protein in fetal serum.
Gerber S, Vial Y, Hohlfeld P, Witkin SS
Am J Obstet Gynecol 2002 Oct;187(4):955-9
 Abstract

Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and
newborn infant.
 Revello MG, Gerna G.
Clin Microbiol Rev 2002 Oct;15(4):680-715
 Abstract

Prenatal diagnosis of congenital cytomegalovirus infection
 Azam A, Vial Y, Fawer C, Zufferey J, Hohlfeld P
Obstet Gynecol 2001 Mar;97(3):443-8 
Abstract 

Congenital cytomegalovirus infection in a neonatal intensive care unit in brazil evaluated by PCR
 and association with perinatal aspects.
 Santos DV, Souza MM, Goncalves SH, et al.
 Rev Inst Med Trop Sao Paulo 2000 May-Jun;42(3):129-32
 Abstract                            

Diagnosis of congenital and perinatal infection bycytomegalovirus using polymerase chain reaction
 Yamamoto AY, Aquino VH, Figueiredo LT, et al.
Rev Soc Bras Med Trop 1998 Jan-Feb;31(1):19-26
 Abstract

FULL-TEXT ARTICLE
 Cytomegalovirus DNA detection on Guthrie cards in patients with neonatal cholestasis.
Fischler B, Rodensjö P, Nemeth A, Forsgren M, Lewensohn-Fuchs I.
Arch. Dis. Child. Fetal Neonatal Ed. 1999 80: F130-F13.  
Paper

  
Treatment
 
           Journal Papers, Abstracts, and Commentaries
 

 
Is a 6-week Course of Ganciclovir Therapy Effective for Chorioretinitis in Infants
with Congenital Cytomegalovirus Infection?
 Shoji K, Ito N, Ito Y, Inoue N,  et al
J Pediatr. 2010 Apr 16
 Abstract
 
Treatment of symptomatic congenital cytomegalovirus infection with intravenous
ganciclovir followed by long-term oral valganciclovir.
Amir J, Wolf DG, Levy I.
Eur J Pediatr. 2010 Mar 16.
Abstract

Antivirals for cytomegalovirus infection in neonates and infants: focus on pharmacokinetics,
formulations, dosing, and adverse events.
Marshall BC, Koch WC. 
Paediatr Drugs. 2009;11(5):309-21.
Abstract

FULL-TEXT ARTICLE
 Congenital CMV infection; diagnosis in symptomatic infants.
 Gandhoke I, Aggarwal R, Hussain SA,  et al z
 Indian J Med Microbiol. 2009 Jul-Sep;27(3):222-5.
 Paper

Treatment of congenital cytomegalovirus infection: implications for future therapeutic strategies.
Nassetta L, Kimberlin D, Whitley R.  
J Antimicrob Chemother. 2009 Mar 14.
Abstract
 
Congenital Cytomegalovirus Infection: Update on Management Strategies.
Schleiss MR.  
Curr Treat Options Neurol. 2008 May;10(3):186-192.
 Abstract
 
Pharmacokinetic and Pharmacodynamic Assessment of Oral Valganciclovir in the Treatment of
Symptomatic Congenital Cytomegalovirus Disease.
Kimberlin DW, Acosta EP, Sánchez PJ, et al
J Infect Dis. 2008 Feb 15
 Abstract
 
Treatment of congenital cytomegalovirus: where are we now?
 Michaels MG.
Expert Rev Anti Infect Ther. 2007 Jun;5(3):441-8
 Abstract
 
Valganciclovir for Congenital CMV Infection: A Pilot Study on Plasma Concentrations
in Newborns.
 Galli L, Novelli A, Chiappini E, et al
Pediatr Infect Dis J. 2007 May;26(5):451-453
 Abstract
 
FULL TEXT PDF ARTICLE
 Antiviral therapy in neonatal cholestatic cytomegalovirus hepatitis.
 Basarir Ozkan T, Mistik R, Dikici B, et al 
BMC Gastroenterol. 2007 Mar 13;7(1):9
Paper
 
Recent advances in the prevention and treatment of congenital cytomegalovirus infections.
 Adler SP, Nigro G, Pereira L.  
Semin Perinatol. 2007 Feb;31(1):10-8.
 Abstract
 
CMV infections of the neonate: prevalence, diagnosis, therapy
 Vochem M.
 Z Geburtshilfe Neonatol. 2003 May-Jun;207(3):114-8.
Abstract
 
Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and
newborn infant.
 Revello MG, Gerna G.
Clin Microbiol Rev 2002 Oct;15(4):680-715
 Abstract
Case Reports/Studies/Literature Reviews
 

           Journal Papers, Abstracts, and Commentaries

 
Congenital cytomegalovirus infection following antenatal negative diagnostic amniotic fluid analysis-
A single center experience.
Ben-Ziv RG, Yogev Y, Peled Y,  et al
J Matern Fetal Neonatal Med. 2012 Apr 10
 Abstract

Delayed presentation of cytomegalovirus retinitis in an infant with severe congenital
cytomegalovirus infection.
Coors LE, Spencer R.
Retina. 2010 Apr;30(4 Suppl):S59-62.
 Abstract

Congenital cytomegalovirus infection; the impact of cerebral cortical malformations.
 Engman ML, Lewensohn-Fuchs I, Mosskin M, Malm G. 
Acta Paediatr. 2010 Apr 30.
 Abstract

Congenital Transmission of Human Immunodeficiency Virus, Cytomegalovirus, and Toxoplasmosis in
a Premature Infant.
 Tan DH, Asztalos E, Douglas D, ry al
 Pediatr Infect Dis J. 2009 Sep 24
 Abstract

Cortical maldevelopment in congenital cytomegalovirus infection transmitted by a woman with |
preexisting immunity.
 Arpino C, Gattinara GC, Rosso M, et al 
J Neurovirol. 2008 Apr;14(2):173-6.
 Abstract
 
CMV-Induced Neonatal Thrombocytopenia: A Case Report and Review of the Literature.
Aslam M, Anderson JL, Guglietti D, Cardwell D.
Am J Perinatol. 2007 Jul;24(7):429-34.
Abstract
 
Colonic stricture mimicking Hirschsprung's disease: a localized cytomegalovirus infection.
Ekema G, Pedersini P, Milianti S, et al;
J Pediatr Surg. 2006 Apr;41(4):850-2.
 Abstract
 
Cytomegalovirus-related congenital nephrotic syndrome with diffuse mesangial sclerosis.
Besbas N, Bayrakci US, Kale G, Cengiz AB, et al  
Pediatr Nephrol. 2006 Mar 8
 Abstract
 
Perineal ulcers in an infant: an unusual presentation of postnatal cytomegalovirus infection.
Hancox JG, Shetty AK, Sangueza OP, Yosipovitch G.  |
J Am Acad Dermatol. 2006 Mar;54(3):536-9.
 Abstract
 
Retrospective diagnosis of congenital infection by cytomegalovirus in the case of one infant.
 Lopez-Pison J, Rubio-Rubio R, Urena-Hornos T, et al  
 Rev Neurol. 2005 Jun 16-30;40(12):733-6.
 Abstract

Placental transfer of ganciclovir in a woman with acquired immunodeficiency syndrome
and cytomegalovirus disease.
Brandy RC, Schleiss MR, Witte DP,et al.
Pediatr Infect Dis J 2002 Aug;21(8):796-7
 Abstract

Perinatal cytomegalovirus infection complicated with pneumonitis and adrenalitis in a
premature infant.
 Hsu ML, Cheng SN, Huang CF
 J Microbiol Immunol Infect 2001 Dec;34(4):297-300
 Abstract
 
Congenital cytomegalovirus infection: three autopsy case reports.
 Ko HM, Kim KS, Park JW, et al
 Korean Med Sci 2000 Jun;15(3):337-42
 Abstract

 Pilot epidemiologic study about transmission of cytomegalovirus from mother to preterm
infant by breastfeeding.
Croly-Labourdette S, Vallet S, Gagneur A, et al  Arch Pediatr. 2006 Apr 6;
Abstract

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Cytomegalovirus Infection