MedICAL ADVOCATES
Children
  ARV Drug Classes
Protease Inhibitors
Nucleoside Reverse Transcriptase Inhibitors
 NNRTIs
 Integrase Inhibitors






 
Pediatric HIV Drug Main Page Pediatric HIV Main Page Home Page
Last Update:  March 15, 2012
 Documents identified with this icon are in Portable Document Format (PDF) and require the Adobe Acrobat Reader
Protease Inhibitors
       

General Reports

          Journal Papers, Abstracts, and Commentaries

 
A WEEK-IN-REVIEW FEATURED REPORT
Boosted protease inhibitors as a therapeutic option in the treatment of HIV-infected children.
Ramos J.
HIV Med. 2009 Oct;10(9):536-47.
 Abstract

A WEEK IN REVIEW FEATURED REPORT
FULL-TEXT PDF ARTICLE
 Outcome of protease inhibitor substitution with nevirapine in HIV-1 infected children.
 Gonzalez-Tome MI, Ramos Amador JT, et al
BMC Infect Dis. 2008 Oct 22;8(1):144
 Paper
 
Two-Year Outcomes of Children on Non-Nucleoside Reverse Transcriptase Inhibitor and
Protease Inhibitor Regimens in a South African Pediatric Antiretroviral Program.
 Jaspan HB, Berrisford AE, Boulle AM.   
Pediatr Infect Dis J. 2008 Sep 24.
 Abstract
 
A WEEK-IN-REVIEW FEATURED REPORT
Neurodevelopmental Functioning in HIV-Infected Infants and Young Children Before and After the
Introduction of Protease Inhibitor-Based Highly Active Antiretroviral Therapy.
 Lindsey JC, Malee KM, Brouwers P, Hughes MD.
Pediatrics. 2007 Feb 12;
 Abstract
 
Protease Inhibitor Combination Therapy, Severity of Illness, and Quality of Life Among
Children With Perinatally Acquired HIV-1 Infection.
Storm DS, Boland MG, Gortmaker SL, et al
 Pediatrics. 2005 Jan 3
 Abstract

Endocrinologic and immunologic factors associated with recovery of growth in children
with human immunodeficiency virus type 1infection treated withprotease inhibitors.
Van Rossum AM, Gaakeer MI, Verweel S , et al 
 Pediatr Infect Dis J 2003 Jan;22(1):70-6
Abstract		  
     
  Protease inhibitor therapy in HIV-infected children.
Feingold AR, Rutstein RM, Meislich D, et al.
AIDS Patient Care STDS 2000 Nov;14(11):589-93
 Abstract		  

Efficacy

          Journal Papers, Abstracts, and Commentaries

  Long-term protease inhibitor-containing therapy results in limited improvement in T cell
function but not restoration of interleukin-12 production in pediatric patients with aids.
Chougnet C Jankelevich S, Fowke K , et al
J Infect Dis 2001 Jul 15;184(2):201-5
Abstract

           Conference Reports, Abstracts, and Posters 

  Compared to Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI), Protease Inhibitor (PI)
Containing Regimens Results in Greater Immune Reconstitution (IR) in Children Failing
Antiretroviral Therapy (ART)
C. RODRIGUEZ, J. LUJAN , M. GHOTIKAR, et al
(45 ICAAC}
 Abstract

Adverse Events

         Journal Papers, Abstracts, and Commentaries

  Endocrinologic and immunologic factors associated with recovery of growth in children
with human immunodeficiency virus type 1infection treated with protease inhibitors.
Van Rossum AM, Gaakeer MI, Verweel S , et al 
 Pediatr Infect Dis J 2003 Jan;22(1):70-6
Abstract

Metabolic abnormalities in HIV type 1-infected children treated and not treated with
protease inhibitors.
Melvin AJ, Lennon S, Mohan KM, Purnell JQ.
AIDS Res Hum Retroviruses 2001 Aug 10;17(12):1117-23
Abstract

  

           Conference Reports, Abstracts, and Posters 

  Protease-inhibitor regimen associated with hypercholesterolemia in an urban
pediatric clinic
H Levitt, R Carter, E Rillamas-Sun, et al
 (15IAC)
 Abstract

Viral Dynamics

         Journal Papers, Abstracts, and Commentaries

  Long-term protease inhibitor-containing therapy results in limited improvement in
T cell function but not restoration of interleukin-12 production in pediatric patients
with AIDS.
Chougnet C, Jankelevich S, Fowke, et al
 J Infect Dis 2001 Jul 15;184(2):201-5        
Abstract
Nucleoside Reverse Transcriptase Inhibitors
       

General Reports

          Journal Papers, Abstracts, and Commentaries
 
 
Role of Non-Nucleoside Reverse Transcriptase Inhibitors in Treating HIV-Infected Children.
Penazzato M, Giaquinto C.
Drugs. 2011 Nov 12;71(16):2131-49
 Abstract

FULL-TEXT PDF ARTICLE
Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children.
Bunupuradah T, Puthanakit T, Kosalaraksa P, et al
AIDS Res Ther. 2011 Oct 26;8(1):40
 Paper

Response to Nonnucleoside Reverse Transcriptase Inhibitor-Based Therapy in HIV-Infected
Children with Perinatal Exposure to Single-Dose Nevirapine.
 Musiime V, Ssali F, Kayiwa J, Namala W, et al
AIDS Res Hum Retroviruses. 2009 Sep 24.
Abstract

Pattern and predictors of immunologic recovery in human immunodeficiency virus-infected children receiving
non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy.
Puthanakit T, Kerr S, Ananworanich J, et al
Pediatr Infect Dis J. 2009 Jun;28(6):488-92.
 Abstract

FULL TEXT PDF ARTICLE
 Baseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic
response to combination therapy in children (PACTG 338).
 Fiscus SA, Kovacs A, Petch LA, et al  
AIDS Res Ther. 2007 Feb 6;4(1):2
Paper

Mutations linked to drug resistance, human immunodeficiency virus type 1
biologic phenotype and their association with disease progression in children
receiving nucleoside reverse transcriptase inhibitors.
Englund JA, Raskino C, Vavro C, et al.
Pediatr Infect Dis J. 2004 Jan;23(1):15-22
 Abstract
 
         Conference Reports, Abstracts, and Posters 
 
 
POSTER
 Safety and Efficacy of NRTI-only Antiretroviral Regimens in HIV-infected Children
 M Neely, R Rutstein, G del Bianco. et al
(17th CROI)
 PDF Poster     Abstract

Treatment outcome of non-nucleoside reverse transcriptase (NNRTI)-based
highly active antiretroviral therapy (HAART) in orphans living in HIV-positive
family-style Thai community
A Siripong, O Tulloch, M Boyd, et al
 (15IAC)
Abstract
 
Resistance

         Journal Papers, Abstracts, and Commentaries

  Resistance to dual nucleoside reverse-transcriptase inhibitors in children
infected with HIV clade A/E.
Lolekha R, Sirivichayakul S, Siangphoe U,et al 
Clin Infect Dis. 2005 Jan 15;40(2):309-12.
 Abstract
Non-Nucleoside Reverse Transcriptase Inhibitors
       

General Reports

          Journal Papers, Abstracts, and Commentaries
 
 
Role of Non-Nucleoside Reverse Transcriptase Inhibitors in Treating HIV-Infected Children.
Penazzato M, Giaquinto C.
Drugs. 2011 Nov 12;71(16):2131-49.
Abstract

Response to Nonnucleoside Reverse Transcriptase Inhibitor-Based Therapy in HIV-Infected Children with Perinatal Exposure to Single-Dose Nevirapine.
Musiime V, Ssali F, Kayiwa J, Namala W, et al
AIDS Res Hum Retroviruses. 2009 Sep 24.
Abstract

Pattern and Predictors of Immunologic Recovery in Human Immunodeficiency Virus-Infected Children
Receiving Non-Nucleoside Reverse Transcriptase Inhibitor-Based Highly Active Antiretroviral Therapy.
 Puthanakit T, Kerr SJ, Ananworanich J,   et al 
Pediatr Infect Dis J. 2009 Apr 28.
 Abstract

Two-Year Outcomes of Children on Non-Nucleoside Reverse Transcriptase Inhibitor and
Protease Inhibitor Regimens in a South African Pediatric Antiretroviral Program.
 Jaspan HB, Berrisford AE, Boulle AM.   
Pediatr Infect Dis J. 2008 Sep 24.
 Abstract
Integrase Inhibitors
       

   Conference Reports, Abstracts, and Posters 

  Absence of Integrase Inhibitor Resistance Mutations in Children Not Treated with Integrase Inhibitors
 J Nelson, A Loftis, K Below, et al
 (19 CROI}
 Abstract

 

Pediatric HIV Drug Main Page Pediatric HIV Main Page Home Page

Photographer: Lutheran World Relief  Photo courtesy of M/MC Photoshare at www.jhuccp.org/mmc  and  is protected by current copyright law 
Pediatric HIV Drug Classes