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  African Malaria Epidemiology/
Incidence/National Challenges
 
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Cameroon 
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Gambia 
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Malawi 
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Kenya  
Niger

 
Rwanda
Senegal
South Africa
Sudan
Tanzania   
Togo
Uganda
Zambia


 

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Last Update:  January 03, 2009    
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Regional/Multinational
         

          Journal Papers, Abstracts, and Commentaries
 
 
Predictions of the impact of malaria control efforts on all-cause child mortality in sub-Saharan
Africa.

Rowe AK, Steketee RW.  
Am J Trop Med Hyg
. 2007 Dec;77(6 Suppl):48-55.
Abstract
 
Over-diagnosis and co-morbidity of severe malaria in African children: a guide for clinicians.
Gwer S, Newton CR, Berkley JA.
Am J Trop Med Hyg.
2007 Dec;77(6 Suppl):6-13.
Abstract
 
The anatomy of a malaria disaster: drug policy choice and mortality in African children.
Hastings IM, Korenromp EL, Bloland PB.
Lancet Infect Dis
. 2007 Sep 18;
Abstract
 
FULL TEXT ARTICLE
Impact of placental Plasmodium falciparum malaria on pregnancy and perinatal outcome in
sub-Saharan Africa: I: introduction to placental malaria.

Uneke CJ.
Yale J Biol Med. 2007 Jun;80(2):39-50.
Paper
 
FULL TEXT ARTICLE
An insight into immunogenic salivary proteins of Anopheles gambiae in African children.
Cornelie S, Remoue F, Doucoure S, et al
Malar J. 2007 Jun 5;6:75.
Paper
 
Ability of mothers to diagnose fever and anaemia in their young children, in a
malaria-endemicregion of West Africa.
Yé Y, Traoré C, Meissner P, et al
Ann Trop Med Parasitol. 2007 Jun;101(4):297-303.
Abstract
 
Methodological issues in the assessment of antimalarial drug treatment: analysis of 13
studies in eight African countries from 2001 to 2004.

Guthmann JP, Pinoges L, Checchi F, et l
Antimicrob Agents Chemother. 2006 Nov;50(11):3734-9
Abstract

High levels of circulating cardiac proteins indicate cardiac impairment in African children
with severe Plasmodium falciparum malaria.

Ehrhardt S, Mockenhaupt FP, Anemana SD, et al
Microbes Infect. 2005 Aug-Sep;7(11-12):1204-10.
Abstract


Cameroon
         


          Journal Papers, Abstracts, and Commentaries
 
  Malaria-an unusual cause of fever in the infant.
Kosina P, Honegr K, Forstl M, Cermakova Z.
Klin Mikrobiol Infekc Lek. 2005 Dec;11(6):229-232.
Abstract
 
Malaria and intestinal helminthiasis in school children of Kumba Urban Area, Cameroon.
Adio MB, Ndamukong KJ, Kimbi HK, Mbuh JV.
East Afr Med J. 2004 Nov;81(11):583-8.
Abstract

Gabon
         

          Journal Papers, Abstracts, and Commentaries

  FULL TEXT ARTICLE
Cytoadherence and Genotype of Plasmodium falciparum Strains from Symptomatic
Children in Franceville, Southeastern Gabon.
Touré FS, Ouwe-Missi-Oukem-Boyer O, Mezui-Me-Ndong J, et al

Clin Med Res. 2007 Jun;5(2):106-13.
Paper

Gambia
         

          Journal Papers, Abstracts, and Commentaries

  Carriage of chloroquine-resistant parasites and delay of effective treatment increase the
risk of severe malaria in Gambian children.

Meerman L, Ord R, Bousema JT
J Infect Dis. 2005 Nov 1;192(9):1651-7.
Abstract

Ghana
         


          Journal Papers, Abstracts, and Commentaries
 
 
FULL-TEXT ARTICLE
Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children:
a randomized, placebo controlled trial.

Kweku M, Liu D, Adjuik M, et al  
PLoS ONE. 2008
;3(12):e4000.
Paper
 
Spatial Variation of Malaria Incidence in Young Children from a Geographically Homogeneous Area
with High Endemicity.
Kreuels B, Kobbe R, Adjei S, et al 
J Infect Dis. 2008 Jan 1;197(1):85-93.
Abstract
 
Intermittent preventive treatment in infants as a means of malaria control: a randomized,
double-blind, placebo-controlled trial in northern ghana.

Mockenhaupt FP, Reither K, Zanger P, et al 

Antimicrob Agents Chemother.
2007 Sep;51(9):3273-81
Abstract

Socio-cultural determinants of treatment delay for childhood malaria in southern Ghana.
Ahorlu CK, Koram KA, Ahorlu C, et al
Trop Med Int Health. 2006 Jul;11(7):1022-31.
Abstract

Limited influence of haptoglobin genotypes on severe malaria in Ghanaian children.
Bienzle U, Eggelte TA, Adjei LA, et al
Trop Med Int Health. 2005 Jul;10(7):668-71
Abstract

Kenya
         


          Journal Papers, Abstracts, and Commentaries
 
 
Survival and haematological recovery of children with severe malaria transfused in accordance to WHO
guidelines in Kilifi, Kenya.
Akech SO, Hassal O, Pamba A, et al
 
Malar J
. 2008 Dec 16;7(1):256

Abstract
 
FULL TEXT ARTICLE
Evidence for over-dispersion in the distribution of clinical malaria episodes in children.
Mwangi TW, Fegan G, Williams TN, et al 

PLoS ONE. 2
008 May 21;3(5):e2196.
Paper
 

FULL TEXT ARTICLE
IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a
short half-life.

Kinyanjui SM, Conway DJ, Lanar DE, Marsh K.
Malar J. 2007 Jun 28;6:82
Paper

FULL TEXT ARTICLE
Increasing Coverage and Decreasing Inequity in Insecticide-Treated Bed Net Use
among Rural Kenyan Children.

Noor AM, Amin AA, Akhwale WS et al.  
PLoS Med
. 2007 Aug 21;4(8):e255
Paper
 
FULL-TEXT ARTICLE
Effect of meteorological factors on clinical malaria risk among children: an assessment using
village-based meteorological stations and community-based parasitological survey.

Yé Y, Louis VR, Simboro S, Sauerborn R.
BMC Public Health. 2007 Jun 8;7:101.
Paper
 
Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan
children.

Idro R, Ndiritu M, Ogutu B, et al
JAMA. 2007 May 23;297(20):2232-40.
Abstract
 
FULL-TEXT ARTICLE
Use of over-the-counter malaria medicines in children and adults in three districts in Kenya:
implications for private medicine retailer interventions.

Abuya TO, Mutemi W, Karisa B, et al
Malar J. 2007 May 10;6:57.
Paper

FULL-TEXT ARTICLE
Heritability of malaria in Africa.
Mackinnon MJ, Mwangi TW, Snow RW, et al
PLoS Med. 2005 Dec;2(12):e340.
Paper

FULL-TEXT ARTICLE
Malaria and nutritional status among pre-school children: results from cross-sectional
surveys in western Kenya.

Friedman JF, Kwena AM, Mirel LB, et al
Am J Trop Med Hyg. 2005 Oct;73(4):698-704
Paper
.
Genomewide analysis of the host response to malaria in Kenyan children.
Griffiths MJ, Shafi MJ, Popper SJ, et al
J Infect Dis. 2005 May 15;191(10):1599-611.
Abstract

Malawi
         

          Journal Papers, Abstracts, and Commentaries
 
  A criteria-based clinical audit on the case-management of children presenting with malaria
at Mangochi District Hospital, Malawi.

Diep PP, Lien L, Hofman J, et al
World Hosp Health Serv. 2007;43(2):21-9
Abstract

Mali
         

          Journal Papers, Abstracts, and Commentaries
 

 
Life-Threatening Malaria in African Children: A Prospective Study in a Mesoendemic
Urban Setting.
Ranque S, Poudiougou B, Traoré A, et al
 
Pediatr Infect Dis J.
2008 Feb;27(2):130-135.
Abstract

Serum antibody levels to glycosylphosphatidylinositols in specimens derived from matched
Malian children with severe or uncomplicated Plasmodium falciparum malaria and healthy

controls.
Cissoko Y, Daou M, Lyke KE, et al
Am J Trop Med Hyg. 2006 Aug;75(2):199-204.
Abstract
 

Association of Schistosoma haematobium infection with protection against acute
Plasmodium falciparum malaria in Malian children.
Lyke KE, Dicko A, Dabo A, et al
Am J Trop Med Hyg. 2005 Dec;73(6):1124-30
Abstract


Niger
         

          Journal Papers, Abstracts, and Commentaries

  Analysis of 1697 cases of childhood malaria treated using intra-rectal Quinimax (QIR) in the
Tilaberi health district in Niger

Landais E, Poisson C, Condamine JL.
Med Trop (Mars). 2007 Oct;67(5):471-6
Abstract

Nigeria
         


          Journal Papers, Abstracts, and Commentaries
 
 
The development of a treatment guideline for childhood malaria in rural Southwest Nigeria using
participatory approach.
Ajayi IO, Oladepo O, Falade CO, et al
 

Patient Educ Couns
. 2008 Dec 17
Abstract
 
FULL TEXT PDF ARTICLE
Assessment of a treatment guideline to improve home management of malaria in children in
rural south-west Nigeria.

Ajayi IO, Falade CO, Bamgboye AE, et al
 
Malar J. 2008 Jan 29;7(1):24
Paper
 
FULL TEXT PDF ARTICLE
In vitro antimalarial activity of methylene blue against field isolates of Plasmodium falciparum
from children in Southwest Nigeria.

Ademowo OG, Nneji CM, A Adedapo AD.
Indian J Med Res. 2007 Jul;126(1):45-9.
Paper
 
FULL TEXT PDF ARTICLE
Epidemiological factors that promote the development of severe malaria anaemia in children
in Ibadan.

Anumudu CI, Okafor CM, Ngwumohaike V, et al
Afr Health Sci. 2007 Jun;7(2):80-5.
Paper
 
Increasing Burden of Childhood Severe Malaria in a Nigerian Tertiary Hospital: Implication
for Control.
Orimadegun AE, Fawole O, Okereke JO, et al 
J Trop Pediatr.
2007 Feb 7;
Abstract
 
Effects of acute Plasmodium falciparum malaria on body weight in children in an
endemic area.
Sowunmi A, Gbotosho GO, Adedeji AA. et al
Parasitol Res. 2007 Feb 25;
Abstract
 
Calcium and phosphate levels in Nigerian children with malaria.
Ayoola OO, Fawole OI, Omotade OO.
Ann Trop Paediatr. 2005 Dec;25(4):303-6.
Abstract
 
Pattern of cerebral malaria in children at the lagos university teaching hospital
Lesi FE, Nwosu SU, Mafe AG, et al
Niger Postgrad Med J. 2005 Dec;12(4):275-9.
Abstract
 
Fatal relapse of hyperreactive malarial splenomegaly (HMS) in a 10-year old Nigerian
female--a case report
Otaigbe BE, Emuren L
Niger J Med. 2005 Oct-Dec;14(4):447-9.
Abstract
 
Plasmodium falciparum malaria in south-west Nigerian children: is the polymorphism of
ICAM-1 and E-selectin genes contributing to the clinical severity of malaria?

Amodu OK, Gbadegesin RA, Ralph SA, et al
Acta Trop. 2005 Sep;95(3):248-55.
Abstract
 
Plasmodium falciparum malaria in Nigerian children during high and low transmission seasons:
gametocyte carriage and response to oral chloroquine.

Adedeji AA, Fehintola FA, Fateye BA, et azl
J Trop Pediatr. 2005 Oct;51(5):288-94.
Abstract
 
Complement factors and circulating immune complexes in children with urinary schistosomiasis
and asymptomatic malaria.

Arinola OG.
Afr J Med Med Sci. 2005 Mar;34(1):9-13.
Abstract

Rwanda
         

          Journal Papers, Abstracts, and Commentaries

  FULL-TEXT PDF ARTICLE
Reduced paediatric hospitalizations for malaria and febrile illness patterns following implementation of
community-based malaria control programme in rural Rwanda.

Sievers AC, Lewey J, Musafiri P, et al  
Malar J. 2008 Aug 27;7(1):167.
Paper

Senegal
         

          Journal Papers, Abstracts, and Commentaries

 
FULL TEXT PDF ARTICLE
Multiplicity of Plasmodium falciparum infection in asymptomatic children in Senegal: relation to
transmission, age and erythrocyte variants.

Vafa M, Troye-Blomberg M, Anchang J,et al 
Malar J. 2008 Jan 23;7(1):17
Paper
 
FULL TEXT ARTICLE
A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal
intermittent preventive treatment for malaria in Senegalese children.
Sokhna C, Cissé B, Bâ el H, et al
PLoS ONE. 2008 Jan 23;3(1):e1471.
Paper

Impact of intermittent preventive anti-malarial treatment on the growth and
nutritional status of preschool children in rural senegal (west Africa).
Ntab B, Cissé B, Boulanger D, et al
Am J Trop Med Hyg. 2007 Sep;77(3):411-7.
Abstract


South Africa
         

          Journal Papers, Abstracts, and Commentaries

  Childhood malaria in a region of unstable transmission and high human immunodeficiency
virus prevalence.
Grimwade K, French N, Mbatha DD,

Pediatr Infect Dis J.
2003 Dec;22(12):1057-1063.
Abstract

Sudan
         

          Journal Papers, Abstracts, and Commentaries

 
Cerebral malaria in children in South Sudan: 8 years experience in 261 cases.
Bartkovjak M, Ianetti R, Kutna K, et al
Neuro Endocrinol Lett. 2007 Jun 10;28(Suppl2):45-46
Abstract
 

FULL-TEXT ARTICLE
Treatment-seeking behaviour for malaria in children under five years of age: implication
for home management in rural areas with high seasonal transmission in Sudan.

Malik EM, Hanafi K, Ali SH, et al
Malar J. 2006 Jul 22;5:60.
Paper


Tanzania
         


          Journal Papers, Abstracts, and Commentaries
 
 
FULL TEXT PDF ARTICLE
Varying efficacy of intermittent preventive treatment for malaria in infants in two similar
trials: public health implications.

Menendez C, Schellenberg D, Macete E, et al  
Malar J
. 2007 Sep 26;6(1):132
Paper
 
Distribution of free untreated bednets bundled with insecticide via an integrated child health
campaign in Lindi Region, Tanzania: lessons for future campaigns.

Skarbinski J, Massaga JJ, Rowe AK, Kachur SP.
Am J Trop Med Hyg. 2007 Jun;76(6):1100-6.
Abstract
 
FULL-TEXT ARTICLE
Antimicrobial resistance predicts death in Tanzanian children with bloodstream infections:
a prospective cohort study.

Blomberg B, Manji KP, Urassa WK, et al
BMC Infect Dis. 2007 May 22;7:43.
Paper

High reinfection rate and treatment failures in children treated with amodiaquine for falciparum
malaria in Muheza villages, Northeastern Tanzania.

Lemnge M, Alifrangis M, Kafuye MY
Am J Trop Med Hyg. 2006 Aug;75(2):188-93
Abstract
 

FULL-TEXT ARTICLE
Role of traditional healers in the management of severe malaria among children below five years
of age: the case of Kilosa and Handeni Districts, Tanzania.

Makundi EA, Malebo HM, Mhame P, et al
Malar J. 2006 Jul 18;5:58.
Paper

Togo
         

          Journal Papers, Abstracts, and Commentaries

  Burden of malaria at community level in children less than 5 years of age in Togo.
Eliades MJ, Wolkon A, Morgah K, et al 

Am J Trop Med Hyg.
2006 Oct;75(4):622-9

Abstract 
 
Evolution of severe pediatric malaria in Togo between 2000 and 2002
Gbadoe AD, Kini-Caussi M, Koffi S, et al
Med Mal Infect. 2006 Jan;36(1):52-4.
Abstract
 

Uganda
         

          Journal Papers, Abstracts, and Commentaries
 
 
FULL TEXT ARTICLE
Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria
in Ugandan children.
Maiteki-Sebuguzi C, Jagannathan P, Yau VM, 
Malar J.
2008 Jun 11;7(1):106.
Paper
 
High risk of neutropenia in HIV-infected children following treatment with artesunate plus
amodiaquine for uncomplicated malaria in Uganda
.
Gasasira AF, Kamya MR, Achan J, et al
Clin Infect Dis. 2008 Apr 1;46(7):985-91.
Abstract

Effects of trimethoprim-sulfamethoxazole and insecticide-treated bednets on malaria among
HIV-infected Ugandan children.

Kamya MR, Gasasira AF, Achan J, et al
AIDS.
2007 Oct 1;21(15):2059-66.
Abstract
 

Combination therapy for uncomplicated falciparum malaria in Ugandan children:
a randomized trial.
Dorsey G, Staedke S, Clark TD, et al
JAMA. 2007 May 23;297(20):2210-9.
Abstract

FULL-TEXT ARTICLE
Decorticate, decerebrate and opisthotonic posturing and seizures in Kenyan children
with cerebral malaria.

Idro R, Otieno G, White S, et al
Malar J. 2005 Dec 7;4:57.
Paper
 

Quality of parental consent in a Ugandan malaria study.
Pace C, Talisuna A, Wendler D, et al
Am J Public Health. 2005 Jul;95(7):1184-9.
Abstract

Zambia
         

          Journal Papers, Abstracts, and Commentaries

 
FULL-TEXT ARTICLE
Paediatric malaria case-management with artemether-lumefantrine in Zambia: a repeat
cross-sectional study.

Zurovac D, Ndhlovu M, Sipilanyambe N, et al
Malar J. 2007 Mar 16;6:31.
Paper

Factors associated with severe anaemia in Zambian children admitted with Plasmodium
falciparum malarial anaemia.

Mulenga M, Malunga P, Bennett S, et al

Ann Trop Paediatr. 2005 Jun;25(2):87-90.
Abstract


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