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Stavudine (Zerit)

Journal Citations: Adverse Events

General Reports
Cutaneous Disorders
Guillain-Barre Syndrome
Gynecomastia
Hepatic Disorders
Metabolic Disorders
Mitochondrial Disorders
Neuropathy
Pancreatitis
Renal Disorders
NRTI Adverse Events

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Last Update: October 26, 2008
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General Reports

Effect of Reducing the Dose of Stavudine on Body Composition, Bone Density, and Markers of
Mitochondrial Toxicity in HIV-Infected Subjects: A Randomized, Controlled Study.
McComsey GA, Re Iii VL, O'Riordan M, et al
Clin Infect Dis. 2008 Apr 15;46(8):1290-1296
Abstract

New questions about an old combination--ddI + d4T.
Proj Inf Perspect 2003 Jan;(35):13-4
Abstract

Adherence, side effects and efficacy of stavudine plus lamivudine plus nelfinavir in treatment-
experienced HIV-infected patients.
Roca B, Gomez CJ, Arnedo A
J Infect 2000 Jul;41(1):50-4
Abstract

Cutaneous Disorders

Long-term subcutaneous tissue changes among antiretroviral-naive persons initiating stavudine, zidovudine,
or abacavir with lamivudine.
Shlay JC, Sharma S, Peng G, et al
J Acquir Immune Defic Syndr. 2008 May 1;48(1):53-62.
Abstract

Guillain-Barre Syndrome

Miller fisher variant of guillain-barre syndrome associated with lactic acidosis and Stavudine therapy.
Shah SS, Rodriguez T, McGowan JP. et al
Clin Infect Dis 2003 May 15;36(10):E131-3
Abstract

Gynecomastia

Gynaecomastia in a male patient during stavudine and didanosine treatment for HIV infection.
Aquilina C, Viraben R.
Int J STD AIDS 2001 Jul;12(7):481-2
Abstract

Hepatic Disorders

FULL TEXT PDF ARTICLE
Dideoxynucleoside HIV reverse transcriptase inhibitors and drug-related hepatotoxicity:
A case report.
Lapadula G, Izzo I, Costarelli S, et al
J Med Case Reports. 2007 May 8;1(1):19
Paper

Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or
zalcitabine.
Walker UA, Bauerle J, Laguno M, et al.
Hepatology. 2004 Feb;39(2):311-7.
Abstract

Miller fisher variant of guillain-barre syndrome associated with lactic acidosis and Stavudine therapy.
Shah SS, Rodriguez T, McGowan JP. et al
Clin Infect Dis 2003 May 15;36(10):E131-3
Abstract

Hypothyroidism

Increased Prevalence of Hypothyroidism among Human Immunodeficiency Virus-Infected Patients:
A Need for Screening.
Beltran S, Lescure FX, Desailloud R, et al.
Clin Infect Dis. 2003 Aug 15;37(4):579-83.
Abstract

Mitochondrial Disorders

Effects of a Nucleoside Reverse Transcriptase Inhibitor, Stavudine, on Glucose Disposal and
Mitochondrial Function in Muscle of Healthy Adults.
Fleischman A, Johnsen S, Systrom DM, et al
Am J Physiol Endocrinol Metab. 2007 Feb 6;
Abstract

Drug-induced increased mitochondrial biogenesis in a liver biopsy.
Kamal MA, French SW.
Exp Mol Pathol. 2004 Dec;77(3):201-4.
Abstract

Neuropathy

Can We Predict Neuropathy Risk before Stavudine Prescription in a Resource-Limited Setting?
Affandi JS, Price P, Imran D, et al
AIDS Res Hum Retroviruses. 2008 Oct 6.
Abstract

Peripheral neuropathy during stavudine-didanosine antiretroviral therapy.
Reliquet V, Mussini JM, Chennebault JM, et al
HIV Med 2001 Apr;2(2):92-6
Abstract

Pancreatitis

Drug-induced acute pancreatitis: a personal contribution
Battillocchi B, Diana M, Dandolo R, et al
Chir Ital 2002 Sep-Oct;54(5):605-12
Abstract

Renal Disorders

Fanconi syndrome and lactic acidosis associated with stavudine and lamivudine therapy.
Nelson M, Azwa A, Sokwala A, et al
AIDS. 2008 Jul 11;22(11):1374-6.
Abstract

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Stavudine Journal Citations: Adverse Events