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Pegylated Interferons
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Last Update:  October 11, 2011
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New and Noteworthy
     

October 2011
 

September 2011
 


Miscellaneous Studies
     

    Journal Papers, Abstracts, and Commentaries
 
 
Peginterferon/ribavirin treatment achieves a higher compliance rate than interferon/ribavirin
combination in patients chronically infected with HCV on methadone maintenance.
Dimitroulopoulos D, Petroulaki E, Manolakopoulos S, et al
Eur J Gastroenterol Hepatol
. 2009
Dec;21(12):1407-12.
Abstract

Comparison of biochemical safety between PEG-IFN alpha-2a and PEG-IFN alpha-2b.
Katano Y, Kumada T, Nakano I, et al
Hepatogastroenterology. 2009 Mar-Apr;56(90):485-91
Abstract

 

General HBV Studies
     

    Journal Papers, Abstracts, and Commentaries
 
  Combination of pegylated interferon and lamivudine for patients with chronic hepatitis B who
have failed treatment.

Sarin SK, Kumar M, Hissar S, Sharma BC.
Hepatobiliary Pancreat Dis Int. 2006 Aug;5(3):374-80
Abstract
 
Pegylated interferon alpha in the treatment of chronic hepatitis B in HBe negative patients
Pawlowska M, Halota W.
Przegl Epidemiol. 2006;60(1):105-8.
Abstract
 
Pegylated interferons for chronic hepatitis B
Craxi A, Cooksley WG.
Antiviral Res. 2003 Oct;60(2):87-9.
Abstract

General HIV/HCV Studies
     

     Journal Papers, Abstracts, and Commentaries
 
 
Randomized Trial Comparing Dose Reduction and Growth Factor Supplementation for Management of Hematological Side Effects in HIV/HCV Patients Receiving Pegylated-Interferon and Ribavirin.
Talal AH, Liu RC, Zeremski M, et al
J Acquir Immune Defic Syndr
. 2011 Aug 26.
Abstract

Peginterferon alfa and ribavirin for chronic hepatitis C in patients eligible for shortened treatment, re-treatment or in HCV/HIV
co-infection: a systematic review and economic evaluation.
Hartwell D, Jones J, Baxter L, Shepherd J.
Health Technol Assess
.
2011 Apr;15(17):1-210.
Abstract

Twelve week post-treatment follow-up predicts sustained virological response to pegylated interferon
and ribavirin therapy in HIV/hepatitis C virus co-infected patients.
Rivero-Juárez A, Mira JA, Pérez-Camacho I,  et al
J Antimicrob Chemother
. 2011 Mar 17.
Abstract

Differences in liver fibrosis and response to pegylated interferon plus ribavirin in
HIV/HCV-coinfected patients with normal vs elevated liver enzymes.
Maida I, Martin-Carbonero L, Sotgiu G, et al
J Viral Hepat
. 2010 Jan 18
Abstract

HIV/Hepatitis C Virus-Coinfected Virologic Responders to Pegylated Interferon
and Ribavirin Therapy More Frequently Incur Interferon-Related Adverse Events
Than Nonresponders Do.
Osinusi A, Rasimas JJ, Bishop R, et al
J Acquir Immune Defic Syndr
. 2010 Jan 23
Abstract

Alpha-interferon versus peg-interferon associated to ribavirin in the treatment of genotype 1
hepatitis C virus and human immunodeficiency virus coinfected patients]

Almeida PR, Tovo CV, Rigo JO, et al
Arq Gastroenterol. 2009 Apr-Jun;46(2):132-7.
Abstract

Efficacy of pegylated interferon plus ribavirin treatment in HIV/hepatitis C virus co-infected patients
receiving abacavir plus lamivudine or tenofovir plus either lamivudine or emtricitabine as nucleoside
analogue backbone.
Mira JA, López-Cortés LF, Barreiro P,  et al 
Antimicrob Chemother.
2008 Oct 13
Abstract
 

HCV RNA in peripheral blood cell subsets in HCV-HIV coinfected patients at the end of PegIFN/RBV treatment
is associated with virologic relapse.

de Felipe B, Leal M, Soriano-Sarabia N, et al 
J Viral Hepat.
2008 Aug 28.
Abstract

Low response to pegylated interferon plus ribavirin in HIV-infected patients with chronic hepatitis C treated
with abacavir.

V
ispo E, Barreiro P, Pineda JA, et al 
Antivir Ther
. 2008;13(3):429-37
Abstract

Efficacy of pegylated interferon and ribavirin for retreatment of chronic HCV infection in HIV co-infected
patients failing a previous standard interferon-based regimen.
Crespo M, Mira JA, Pineda JA, et al  
J Antimicrob Chemother. 2008 Jun 21.
Abstract

The use of trough ribavirin concentration to predict sustained virological response and
haematological toxicity in HIV/HCV-co-infected patients treated with ribavirin and
pegylated interferon.

Marucco DA, de Requena DG, Bonora S, Tet al 
J Antimicrob Chemother.
2008 Jan 31
Abstract
 

Baseline CD4 Cell Count and Outcome of Pegylated Interferon Plus Ribavirin Therapy in
HIV/Hepatitis C Virus-Coinfected Patients.
Valerio L, Yazdanpanah Y, Poizot-Martin I, et al
 
J Acquir Immune Defic Syndr.
2007 Oct 11
Abstract
 
Response rates to pegylated interferon and ribavirin in HCV/HIV coinfection:
a research synthesis.

Shire NJ, Welge JA, Sherman KE.
J Viral Hepat. 2007 Apr;14(4):239-48.
Abstract
 
     Conference Reports, Abstracts, and Posters 
 
 
POSTER
Effect of Accompanying Antiretroviral Drugs on Virologic Response to PEG-IFN and Ribavirin
in HIV/HCV-Co-infected Patients

J Berenguer, M von Wichmann, C Quereda, et al
(17th CROI)
PDF Poster
     Abstract
 
POSTER
I
nterleukin 28 B Genotype Is a Potent Predictor of Response to Therapy with Pegylated
Interferon plus Ribavirin in HIV/HCV Co-infected Patients

J Pineda, A Caruz, Á Camacho, et al
(17th CROI)
PDF Poster
     Abstract

Insulin Resistance Impairs Sustained Virologic Response to Interferon plus Ribavirin
in HIV/HCV-co-infected Patients

P Ryan, S Resino, P Miralles, et al 
(16 CROI
Abstract

POSTER
Duration of Viral HCV Supression as a Predictor of Sustained Virological Response in
HIV/HCV-co-infected Patients Treated with Pegylated-Interferon + Ribavirin

C Quereda, F Ferrere, A Moreno, et al 
(16 CROI)
PDF Poster
     Abstract

Effect of a Widely Used HCV Therapy on the Current Distribution of HCV Genotypes in a Large Cohort of
HIV/HCV-co-infected Patients in Spain

E Vispo, A Madejon, P Tuma, et al
(16 CROI)
Abstract
 
POSTER
Efficacy of Pegylated Interferon + Ribavirin Treatment in HIV/HCV-co-infected Patients
Receiving Abacavir + Lamivudine or Tenofovir + either Lamivudine or Emtricitabine as
Nucleoside Analogue Backbone

J Mira, L Lopez-Cortes, P Barreiro, et al
(15th CROI)

PDF Poster     Abstract

POSTER
Antiretroviral Regimens including Tenofovir or Stavudine + Lamivudine as NRTI Backbone
Are Associated with Higher Sustained Virological Response Rate to Pegylated Interferon
and Ribavirin Treatment in HIV/HCV-co-infected Patients

J. Mira, R Carrillo-Gómez, A Gutierrez
15th CROI
PDF Poster
     Abstract


General HDV Studies
     

    Journal Papers, Abstracts, and Commentaries
 
  Resolution of chronic hepatitis Delta after 1 year of combined therapy with pegylated interferon,
tenofovir and emtricitabine.
Mansour W, Ducancelle A, Le Gal F,  et al 
J Clin Virol
. 2009 Nov 12.

Abstract


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