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Nevirapine (Viramune)
 
African PMTCT Studies
 
Multinational
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DR Congo
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Multinational
 
Multinational

         Journal Papers, Abstracts, and Commentaries

 
FULL-TEXT ARTICLE
 Performance of HIV Prevention of Mother-To-Child Transmission Programs in Sub-Saharan Africa: Longitudinal Assessment of 64 Nevirapine-Based Programs Implemented in 25 Countries, 2000-2011.
 Ladner J, Besson MH, Rodrigues M, et al
PLoS One. 2015 Jun 22;10(6):e0130103
Paper

Efficacy and Safety of an Extended Nevirapine Regimen in Infants of Breastfeeding Mothers With HIV-1 Infection for Prevention of HIV-1 Transmission (HPTN 046):
18-Month Results of a Randomized, Double-Blind, Placebo-Controlled Trial.
 Fowler MG, Coovadia H, Herron CM,  et al
J Acquir Immune Defic Syndr. 2014 Mar 1;65(3):366-74
 Abstract

Coverage of nevirapine-based services to prevent mother-to-child HIV transmission in
4 African countries.
 Stringer EM, Ekouevi DK, Coetzee D,  et al
JAMA. 2010 Jul 21;304(3):293-302.
 Abstract

Effects of Nevirapine, Compared with Lamivudine, on Lipids and Lipoproteins in HIV-1-
Uninfected Newborns: The Stopping Infection from Mother-to-Child via Breast-Feeding
in Africa Lipid Substudy.
 Sankatsing RR, Wit FW, Pakker N, et al
J Infect Dis. 2007 Jul 1;196(1):15-22.
 Abstract
 
Safety of nevirapine-containing antiretroviral triple therapy regimens to prevent vertical
transmission in an African cohort of HIV-1-infected pregnant women.
 Marazzi MC, Germano P, Liotta G, Guidotti G, et  al  
HIV Med. 2006 Jul;7(5):338-44
 Abstract

Nevirapine and zidovudine at birth to reduce perinatal transmission of HIV in an
African setting: a randomized controlled trial.
 Taha TE, Kumwenda NI, Hoover DR et al 
JAMA. 2004 Jul 14;292(2):202-9
 Abstract
CÔte d'Ivoire
 

         Journal Papers, Abstracts, and Commentaries

 
Nevirapine for the Prevention of Mother-to-Child Transmission of HIV: A Nation-Wide Coverage Survey in Côte d'Ivoire.
 Coffie PA, Kanhon SK, Touré H,  et al
J Acquir Immune Defic Syndr. 2011 Jul;57 Suppl 1:S3-8.
 Abstract

Pregnancy outcomes in women exposed to efavirenz and nevirapine: an appraisal of the
IeDEA West Africa and ANRS databases, Abidjan, Côte d'Ivoire.
 Ekouevi DK, Coffie PA, Ouattara E,  et al
J Acquir Immune Defic Syndr. 2010 Nov 13
 Abstract

FULL-TEXT PDF ARTICLE
Incidence and risk factors of severe adverse events with nevirapine-based
antiretroviral therapy in HIV-infected women. MTCT-Plus program, Abidjan,
Cote d'Ivoire.
 Coffie PA, Tonwe-Gold B, Tanon AK,  et al
BMC Infect Dis. 2010 Jun 24;10(1):188
 Paper

Transmission Rates in Consecutive Pregnancies Exposed to Single-Dose Nevirapine in
Soweto, South Africa and Abidjan, Cote d'Ivoire.
 Martinson NA, Ekouevi DK, Dabis F, et al
J Acquir Immune Defic Syndr. 2007 Apr 12
 Abstract
 
Low Risk of Nevirapine Resistance Mutations in the Prevention of Mother-to-Child Transmission
of HIV-1: Agence Nationale de Recherches sur le SIDA Ditrame Plus, Abidjan, Cote d'Ivoire.
 Chaix ML, Ekouevi DK, Rouet F, et al   
J Infect Dis. 2006 Feb 15;193(4):482-7.
Abstract

Characterization of Nevirapine (NVP) Resistance Mutations and HIV Type 1 Subtype in
Women from Abidjan (Cote d'Ivoire) After NVP Single-Dose Prophylaxis of HIV Type 1
Mother-to-Child Transmission.
 Toni TD, Masquelier B, Lazaro E, et al
AIDS Res Hum Retroviruses. 2005 Dec;21(12):1031-4.
 Abstract
 
DR Congo
 

         Journal Papers, Abstracts, and Commentaries
 
Feasibility of prevention of perinatal HIV infection by nevirapine in rural areas of the
northeast Democratic Republic of Congo, 2002-2004.
 Kirere Mathe M, Sondag-Thull D, Lepage P.
J Med Virol. 2008 Mar 21;80(5):772-776
 Abstract

Feasibility of HIV prophylaxis with nevirapine in a northeastern rural area of the
Democratic Republic of the Congo.
Mathe MK, Lepage P.
 Sante. 2007 Apr-Jun;17(2):97-101
 Abstract
Kenya
 

         Journal Papers, Abstracts, and Commentaries
 
Pregnancy rates in HIV-positive women using contraceptives and efavirenz-based or nevirapine-based antiretroviral therapy in Kenya: a retrospective cohort study.
 Patel RC, Onono M, Gandhi M,  et al
Lancet HIV. 2015 Nov;2(11):e474-82
 Abstract

Nevirapine-Associated Hepatotoxicity and Rash among HIV-Infected Pregnant Women in Kenya.
 Peters PJ, Polle N, Zeh C,   ei  al
J Int Assoc Physicians AIDS Care (Chic). 2011 Oct 21
 Abstract

Self-reported adherence to single dose nevirapine in the prevention of mother to child
transmission of HIV at Kitale District Hospital.
Bii SC, Otieno-Nyunya B, Siika A, Rotich JK. et al
East Afr Med J. 2007 Dec;84(12):571-6.
 Abstract

Intrapartum and Neonatal Single-Dose Nevirapine Compared with Zidovudine for
for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda:
HIVNET 012 randomised trial.
Guay LA, Musoke P, Fleming T, et al
Lancet. 1999 Sep 4;354(9181):795-802.
 Abstract
Malawi
 

         Journal Papers, Abstracts, and Commentaries
 
 
FULL-TEXT ARTICLE
The impact of HBV or HCV infection in a cohort of HIV-infected pregnant women receiving a nevirapine-based antiretroviral regimen in Malawi.
 Andreotti M, Pirillo MF, Liotta G,  et al
BMC Infect Dis. 2014 Apr 4;14(1):180.
Paper

FULL-TEXT PDF ARTICLE
 Prevention of mother-to-child transmission of HIV infection: Views and perceptions
about swallowing nevirapine in rural Lilongwe, Malawi.
 O'Gorman DA, Nyirenda LJ, Theobald SJ.
BMC Public Health. 2010 Jun 21;10(1):354.
Paper

Prevention of mother-to-child transmission: program changes and the effect on uptake
of the HIVNET 012 regimen in Malawi.
 Moses A, Zimba C, Kamanga E, et al  
AIDS. 2008 Jan 2;22(1):83-7
 Abstract

Resistance after single-dose nevirapine prophylaxis emerges in a high proportion of
Malawian newborns.
 Eshleman SH, Hoover DR, Chen S, et al   
AIDS. 2005 Dec 2;19(18):2167-2169
 Abstract

   
Mozambique
 
         Journal Papers, Abstracts, and Commentaries
 
  Antiretroviral-Associated Toxicity Among HIV-1-Seropositive Pregnant Women in
Mozambique Receiving Nevirapine-Based Regimens.
 Jamisse L, Balkus J, Hitti J, et al
 J Acquir Immune Defic Syndr. 2007 Jan 25;
 Abstract
 
Rwanda
 
          Journal Papers, Abstracts, and Commentaries
 
 
FULL-TEXT ARTICLE
 Couples voluntary counseling and testing and nevirapine use in antenatal clinics in two
African capitals: a prospective cohort study.
 Conkling M, Shutes EL, Karita E,  et al z
 J Int AIDS Soc. 2010 Mar 15;13(1):10.
 Paper
South Africa
 
         Journal Papers, Abstracts, and Commentaries
 
 
Persistence of HIV-drug-resistance among South African Children given Nevirapine to Prevent Mother-to-Child-Transmission.
 Kanthula R, Rossouw T, Feucht UD, et al
AIDS. 2017 Mar 15.
Abstract

Risk of nevirapine-associated Stevens-Johnson syndrome among HIV-infected pregnant women: the Medunsa National Pharmacovigilance Centre, 2007 - 2012.
 Dube N, Adewusi E, Summers R.
 S Afr Med J. 2013 May;103(5):322-5.
Abstract

Nevirapine plasma concentrations in premature infants exposed to single-dose nevirapine for prevention
of mother-to-child transmission of HIV-1.
 Mugabo P, Els I, Smith J, Rabie H,  et al
S Afr Med J. 2011 Sep 5;101(9):655-658.
 Abstract

First-line antiretroviral therapy after single-dose nevirapine exposure in South Africa: a cost-effectiveness analysis
of the OCTANE trial.
 Ciaranello AL, Lockman S, Freedberg KA,  et al
AIDS. 2011 Feb 20;25(4):479-492.
 Abstract

Determinants of adherence to a single-dose nevirapine regimen for the prevention of
mother-to-child HIV transmission in Gert Sibande district in South Africa.
 Peltzer K, Mlambo M, Phaswana-Mafuya N, Ladzani R. 
Acta Paediatr. 2010 Feb 8
 Abstract

Persistent Minority K103N Mutations among Women Exposed to Single-Dose Nevirapine and
Virologic Response to Nonnucleoside Reverse-Transcriptase Inhibitor-Based Therapy.
 Coovadia A, Hunt G, Abrams EJ, et al
Clin Infect Dis. 2009 Jan 9.
 Abstract
 
Incidence of nevirapine-associated hepatitis in an antenatal clinic.
 Black V, Rees H.
S Afr Med J. 2008 Feb;98(2):116-
 Abstract
 
Operational effectiveness of single-dose nevirapine in preventing mother-to-child transmission
of HIV.
 Colvin M, Chopra M, Doherty T, et al
Bull World Health Organ. 2007 Jun;85(6):466-473.
 Abstract
 
Transmission Rates in Consecutive Pregnancies Exposed to Single-Dose Nevirapine in
Soweto, South Africa and Abidjan, Cote d'Ivoire.
 Martinson NA, Ekouevi DK, Dabis F, et al
J Acquir Immune Defic Syndr. 2007 Apr 12
 Abstract
 
A randomized trial of two postexposure prophylaxis regimens to reduce mother-to-child
HIV-1 transmission in infants of untreated mothers.
 Gray GE, Urban M, Chersich MF, et al 
AIDS. 2005 Aug 12;19(12):1289-97.
 Abstract

Emergence of Drug-Resistant HIV-1 after Intrapartum Administration of Single-Dose
Nevirapine Is Substantially Underestimated.
 Johnson JA, Li JF, Morris L, et al 
J Infect Dis. 2005 Jul 1;192(1):16-23.
 Abstract
   
Tanzania
 

         Journal Papers, Abstracts, and Commentaries
 
  Outcome of Different Nevirapine Administration Strategies in Preventing Mother-to-Child
Transmission (PMTCT) Programs in Tanzania and Uganda
Karcher H, Kunz A, Poggensee G, et al
MedGenMed. 2006 Apr 12;8(2):12.
Abstract

 

Uganda
 

         Journal Papers, Abstracts, and Commentaries
 
Suboptimal Nevirapine Steady-State Pharmacokinetics During Intrapartum Compared
With Postpartum in HIV-1-Seropositive Ugandan Women.
 Lamorde M, Byakika-Kibwika P, Okaba-Kayom V, et al
J Acquir Immune Defic Syndr. 2010 Jul 8
 Abstract

In Utero HIV Infection Is Associated with an Increased Risk of Nevirapine Resistance in
Ugandan Infants Who Were Exposed to Perinatal Single Dose Nevirapine.
 Church JD, Mwatha A, Bagenda D, et al 
AIDS Res Hum Retroviruses. 2009 Jun 24.
 Abstract

Analysis of Nevirapine (NVP) Resistance in Ugandan Infants Who Were HIV Infected Despite
Receiving Single-Dose (SD) NVP versus SD NVP Plus Daily NVP Up to 6 Weeks of Age to
Prevent HIV Vertical Transmission.
 Church JD, Omer SB, Guay LA, et al 
J Infect Dis. 2008 Aug 6.
Abstract

Effectiveness of repeat single-dose nevirapine for prevention of mother-to-child transmission of
HIV-1 in repeat pregnancies in Uganda.
 McConnell M, Bakaki P, Eure C, et al 
J Acquir Immune Defic Syndr. 2007 Nov 1;46(3):291-6
 Abstract
 
Effectiveness of Repeat Single-Dose Nevirapine for Prevention of Mother-to-Child Transmission of
HIV-1 in Repeat Pregnancies, Uganda.
 McConnell MS, Bakaki P, Eure C, et al
J Acquir Immune Defic Syndr. 2007 Aug 2;
 Abstract
 
Outcome of Different Nevirapine Administration Strategies in Preventing Mother-to-Child
Transmission (PMTCT) Programs in Tanzania and Uganda
Karcher H, Kunz A, Poggensee G, et al
MedGenMed. 2006 Apr 12;8(2):12.
Abstract
 
Maternal Self-Medication and Provision of Nevirapine to Newborns by Women in Rakai, Uganda.
 Kagaayi J, Dreyfuss ML, Kigozi G, et al  
J Acquir Immune Defic Syndr. 2005 May 1;39(1):121-124
 Abstract
 
Comparison of Mother-to-Child Transmission Rates in Ugandan Women With Subtype
A Versus D HIV-1 Who Received Single-Dose Nevirapine Prophylaxis: HIV Network for
Prevention Trials 012.
 Eshleman SH, Guay LA, Mwatha A, et al 
J Acquir Immune Defic Syndr. 2005 Aug 15;39(5):593-597.
 Abstract
 
Nevirapine (NVP) Resistance in Women with HIV-1 Subtype C, Compared with Subtypes
A and D, after the Administration of Single-Dose NVP.
 Eshleman SH, Hoover DR, Chen S, et 
J Infect t Dis. 2005 Jul 1;192(1):30-6
 Abstract

ntrapartum and Neonatal Single-Dose Nevirapine Compared with Zidovudine for
Prevention of Mother-to-Child Transmission of HIV-1 in Kampala, Uganda:
Randomized Trial (HIVNET 012)
Guay LA, Musoke P, Fleming T, et al.
Lancet 1999 Sep 4;354(9181):795-802  
Abstract

          Conference Reports, Abstracts, and Posters
 

 
Adherence patterns seen among HIV pregnant women on antiretroviral therapy (ART) and on combination zidovudine/sdNVP prophylaxis for prevention of mother-to-child transmission of HIV (PMTCT), in the Mulago National Referral Hospital, Kampala, Uganda
J. Nabweteme-Mugerwa, Z. Namukwaya, E. Namara-Lugolobi, et al
 (XIX International AIDS Conference)
 Abstract
Zambia
 
         Journal Papers, Abstracts, and Commentaries
 
 
In-Home HIV Testing and Nevirapine Dosing by Traditional Birth Attendants in Rural Zambia: A Feasibility Study.
 Brennan AT, Thea DM, Semrau K, et al
J Midwifery Womens Health. 2013 Sep 23.
Abstract

Peripartum nevirapine exposure and subsequent clinical outcomes among
HIV-infected women receiving antiretroviral therapy for at least 12 months.
 Chintu N, Giganti MJ, Putta NB, et al
Trop Med Int Health. 2010 May 7.
 Abstract

FULL-TEXT ARTICLE
 Couples voluntary counseling and testing and nevirapine use in antenatal clinics in two
African capitals: a prospective cohort study.
 Conkling M, Shutes EL, Karita E,  et al z
 J Int AIDS Soc. 2010 Mar 15;13(1):10.
 Paper

A cluster-randomized trial of enhanced labor ward-based PMTCT services to increase nevirapine
coverage in Lusaka, Zambia.
 Megazzini KM, Sinkala M, Vermund SH,  et al 
AIDS. 2010 Jan 28;24(3):447-55.
 Abstract

A cluster-randomized trial of enhanced labor ward-based PMTCT services to increase
nevirapine coverage in Lusaka, Zambia.
 Megazzini KM, Sinkala M, Vermund SH, et al
AIDS. 2009 Nov 18.
Abstract

Predictors of Rapid HIV Testing Acceptance and Successful Nevirapine Administration in Zambian
Labor Wards.
 Megazzini KM, Chintu N, Vermund SH, et al
J Acquir Immune Defic Syndr. 2009 Jun 26.
 Abstract

Mortality and Virologic Outcomes After Access to Antiretroviral Therapy Among a Cohort of HIV-Infected
Women Who Received Single-Dose Nevirapine in Lusaka, Zambia.
 Kuhn L, Semrau K, Ramachandran S, et al
J Acquir Immune Defic Syndr. 2009 Jun 5.
 Abstract

FULL-TEXT PDF ARTICLE
Reuse of single-dose nevirapine in subsequent pregnancies for the prevention of
mother-to-child HIV transmission in
Lusaka, Zambia: A cohort study.
 Walter J, Kuhn L, Kankasa C, et al 
BMC Infect Dis. 2008 Dec 30;8(1):172.
 Paper
 
Zimbabwe
 
         Journal Papers, Abstracts, and Commentaries
 
 
FULL-TEXT PDF ARTICLE
 Non-adherence to the single dose nevirapine regimen for the prevention of mother-to-child
transmission of HIV in Bindura town, Zimbabwe: a cross-sectional analytic study.
 Kuonza LR, Tshuma CD, Shambira GN, Tshimanga M.
 BMC Public Health. 2010 Apr 28;10(1):218.
 Paper

A randomized, double-blind, placebo-controlled trial of combined nevirapine and zidovudine
compared with nevirapine alone in the prevention of perinatal transmission of HIV in
Zimbabwe.
 Thistle P, Spitzer RF, Glazier RH, et al 
Clin Infect Dis. 2007 Jan 1;44(1):111-9
 Abstract
 
   

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 African Nevirapine PMTCT Studies