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Nevirapine (Viramune)
 
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Last Update:  June 28, 2008
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New and Noteworthy
       
June 2008
 
General Reports
 

      Journal Papers, Abstracts, and Commentaries

  Nevirapine: a review of its use in the prevention and treatment of  paediatric HIV  infection.
Bardsley-Elliot A, Perry CM. 
Paediatric Drugs 2000;Sept-Oct (5): 373-407.
Abstract
 		  
             Conference Reports, Abstracts, and Posters
 
  Nevirapine Exposure with WHO Pediatric Weight Band Dosing--Enhanced Therapeutic Concentrations
Predicted Based on Extensive International Pharmacokinetic Experience
 E Capparelli, D Kabamba, T Cressey,  D Burger
(15th CROI)
 Abstracts
Pharmacokinetics
       
      Journal Papers, Abstracts, and Commentaries
 
 
CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical
response in HIV-1-infected children.
 Saitoh A, Sarles E, Capparelli E, et al 
AIDS. 2007 Oct 18;21(16):2191-9.
 Abstract

Pharmacokinetics of nevirapine in HIV-infected children receiving an adult fixed-dose combination
of stavudine, lamivudine and nevirapine.
Chokephaibulkit K, Plipat N, Cressey TR, et al 
AIDS. 2005 Sep 23;19(14):1495-1499
 Abstract
 
             Conference Reports, Abstracts, and Posters
 
  POSTER
 Pharmacokinetics of Nevirapine, Stavudine, and Lamivudine in HIV-infected Children in
Zambia Treated with Pediatric Fixed-dose Combination Tablets
 D Kabamba, R L'homme, F Ewings, et al 
(14 CROI)
 PDF Poster    Abstract
Resistance
 
    Journal Papers, Abstracts, and Commentaries
 
 
Impact of NVP plasma concentration on selection of resistant virus in mothers who
received single dose NVP to prevent perinatal HIV-1 transmission and persistence of
resistant virus in their infected children.
 Chaix ML, Ekouevi DK, Peytavin G, et al
Antimicrob Agents Chemother. 2006 Dec 18;
 Abstract
 
Selection and Persistence of Viral Resistance in HIV-Infected Children After Exposure to
Single-Dose Nevirapine
 Martinson NA, Morris L, Gray G, et al 
J Acquir Immune Defic Syndr. 2006 Nov 16;
Abstract

Need for Therapeutic Drug Monitoring in HIV-1 Infected Children Receiving Efavirenz Doses
according to International Guidelines.
von Hentig N, Koenigs C, Elanjikal S, et al
Eur J Med Res. 2006 Sep 29;11(9):377-80.
 Abstract
   

             Conference Reports, Abstracts, and Posters

 
Analysis of NVP Resistance in Ugandan Infants Who Were HIV-infected despite Receiving
Single-dose Nevirapine vs Single-dose NVP Plus up to 6 Weeks of Daily NVP to Prevent HIV
Vertical Transmission
 J Church, S Omer, L Guay, et al   
(15th CROI)
 Abstract

Selection of Resistance Mutations in Children Receiving Prophylaxis with Lamivudine or
Nevirapine for the Prevention of Postnatal Transmission of HIV
 M  Giuliano, C Galluzzo, E Germinario, et al  
 (12 CROI)
 Abstract

Genotypic resistance profiles in HIV-1 reverse transcriptase after 24-week therapy with
nevirapine-based HAART in antiretroviral naïve Thai HIV-infected children
T Puthanakit, V Sirisanthana, S Sirivichayakul, et al
 (15IAC)
 Abstract
 
Adverse Events
 
           Journal Papers, Abstracts, and Commentaries  
 
  Nevirapine-Associated Rash With Eosinophilia and Systemic Symptoms in a Child With
Human Immunodeficiency Virus Infection.
Santos RP, Ramilo O, Barton T.
Pediatr Infect Dis J. 2007 Nov;26(11):1053-1056.
Abstract

          Conference Reports, Abstracts, and Posters

  POSTER
 Hepatotoxicity Associated with Nevirapine Use in HIV-infected Children
 M Baylor, O Ayime, M Truffa,  et al
 (12 CROI)
PDF Poster   Abstract		  
Diagnostics/Monitoring
 

              Journal Papers, Abstracts, and Commentaries

  Nevirapine Concentration in Nonstimulated Saliva: An Alternative to Plasma Sampling in
Children with Human Immunodeficiency Virus Infection.
 Rakhmanina NY, Capparelli EV, van den Anker JN. et al 
Ther Drug Monit. 2007 Feb;29(1):110-117
 Abstract
 
  Need for Therapeutic Drug Monitoring in HIV-1 Infected Children Receiving Efavirenz Doses
according to International Guidelines.
 von Hentig N, Koenigs C, Elanjikal S, et al
 Eur J Med Res. 2006 Sep 29;11(9):377-80.
 Abstract		  

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