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Delavirdine (Rescriptor)
 
Journal Citations


General Reports
Pharmacokinetics
Drug/Drug Interactions
Resistance
Adverse Events
Efficacy




 


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Last Update:  December 08, 2014
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General Reports
         

 
Solid lipid nanoparticles comprising internal Compritol 888 ATO, tripalmitin and cacao butter for encapsulating and
releasing stavudine, delavirdine and saquinavir.
Kuo YC, Chung CY.
Colloids Surf B Biointerfaces
. 2011
Abstract

Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: Introducing
a diketoacid functionality into delavirdine.

Wang Z, Vince R.  
Bioorg Med Chem. 2008 Feb 8
Abstract
 

Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by
polybutylcyanoacrylate, methylmethacrylate-sulfopropylmethacrylate, and solid lipid

nanoparticles.
Kuo YC, Su FL
Int J Pharm
. 2007 Mar 12
Abstract

Pharmacokinetics
         

 
Population Pharmacokinetics of Delavirdine and N-Delavirdine in HIV-Infected Individuals.
Smith PF, Dicenzo R, Forrest A, et al
Clin Pharmacokinet. 2005;44(1):99-109.
Abstract

Pharmacokinetics of Ritonavir and Delavirdine in Human Immunodeficiency Virus-Infected Patients.
Shelton MJ, Hewitt RG, Adams J, et al.
Antimicrob Agents Chemother
2003 May;47(5):1694-1699
Abstract

 

Drug-Drug Interactions
         

  Pharmacokinetic interaction between amprenavir and delavirdine: Evidence of induced clearance by amprenavir.
Tran JQ, Petersen C, Garrett M, et al.

Clin Pharmacol Ther
2002 Dec;72(6):615-626
Abstract
 

Resistance
 

  Effects of the G190A substitution of HIV reverse transcriptase on phenotypic susceptibility
of patient isolates to delavirdine.
Uhlmann EJ, Tebas P, Storch GA ,et al 

J Clin Virol.
2004 Nov;31(3):198-203.
Abstract
 
  FULL-TEXT ARTICLE
Delavirdine in Combination with Zidovudine in Treatment of Human Immunodeficiency Virus
Type 1-Infected Patients: Evaluation of Efficacy and Emergence of Viral Resistance in a
Randomized, Comparative Phase III Trial

Joly V , Moroni M, Concia E,
Antimicrob Agents
Chemother  2000 Nov;44(11):3155-3157
 Paper

Adverse Events
 

  Delavirdine malabsorption in HIV-infected subjects with spontaneous
gastric hypoacidity.

Shelton MJ, Hewitt RG, Adams JM, et al.

J Clin Pharmacol
2003 Feb;43(2):171-9
Abstract

Efficacy
 

FULL-TEXT ARTICLE
Delavirdine in Combination with Zidovudine in Treatment of Human Immunodeficiency Virus
Type 1-Infected Patients: Evaluation of Efficacy and Emergence of Viral Resistance in a
Randomized, Comparative Phase III Trial

Joly V, Moroni M, Concia E,
et al;
Antimicrob Agents Chemother 2000 Nov;44(11):3155-3157
Paper

FULL-TEXT ARTICLE
ACTG 260: a Randomized, Phase I-II, Dose-Ranging Trial of the Anti-Human
Immunodeficiency Virus Activity of Delavirdine Monotherapy.

Para MF, Meehan P, Holden-Wiltse J, et al.
Antimicrob Agents Chemother 1999 Jun;43(6):1373-1378
Paper
FULL-TEXT ARTICLE
Delavirdine Susceptibilities and Associated Reverse Transcriptase Mutations in
Human Immunodeficiency Virus Type 1 Isolates from Patients in a Phase I/II Trial of
Delavirdine Monotherapy (ACTG 260)
Demeter LM, Shafer RW, Meehan PM, et al.
Antimicrob Agents Chemother 2000 Mar;44(3):794-797
Paper


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Delavirdine Journal Citations