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Adefovir Dipivoxil (Hepsera)
 
Journal Abstracts, Posters, and
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Last Update:  May 22, 2008
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General Reports
                

 
Adefovir dipivoxil compassionate use program in Spain: efficacy and resistance analysis
Buti M, Rodríguez Frías F, Calleja JL, et al
Med Clin (Barc). 2007 Oct 27;129(15):566-70
Abstract
 
Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant
hepatitis B: Final long-term results.
Schiff E, Lai CL, Hadziyannis S, et al  
Liver Transpl. 2007 Jan 11;13(3):349-360
Abstract
 
Inhibition of human liver microsomal cytochrome P450 activities by adefovir and tenofovir.
Nekvindova J, Masek V, Veinlichova A, et al 
Xenobiotica. 2006 Dec;36(12):1165-77.
Abstract
 
Functional involvement of multidrug resistance associated protein 4 (MRP4/ABCC4)
in the renal elimination of the anti-viral drugs, adefovir and tenofovir.

Imaoka T, Kusuhara H, Adachi M, et al 
Mol Pharmacol. 2006 Nov 16;
Abstract
 
Pharmacokinetics, safety and tolerance of single- and multiple-dose adefovir dipivoxil
in healthy Chinese subjects.

Sun DQ, Wang HS, Ni MY, Wang BJ, Guo RC.

Br J Clin Pharmacol. 2006 Jul 21;
Abstract

Systemic and renal pharmacokinetics of adefovir and tenofovir upon coadministration.
Kearney BP, Ramanathan S, Cheng AK   
J Clin Pharmacol.
2005 Aug;45(8):935-40.
Abstract


HBV/HIV Indications
                

 
Randomized controlled study of tenofovir and adefovir in chronic hepatitis B virus and
HIV infection: ACTG A5127.
Peters MG, Andersen J, Lynch P, et al
 Hepatology. 2006 Nov;44(5):1110-6
Abstract
 
The renal tolerance of low-dose adefovir dipivoxil by lamivudine-resistant individuals
co-infected with hepatitis B and HIV.
Hannon H, Isnard Bagnis C, et al.
Nephrol Dial Transplant.
2004 Feb; 19(2):

Abstract