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Abacavir (Ziagen)
 
Pediatric Index

US Treatment Guidelines
Efficacy
Adherence
 Salvage Therapy





 

 
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Last Update:  September 14, 2007
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Pharmacokinetics
 

    Journal Papers, Abstracts, and Commentaries

  Abacavir pharmacokinetics in human immunodeficiency virus-infected children ranging in age
from 1 month to 16 years: a population analysis.
 Jullien V, Urien S, Chappuy H, et al  
J Clin Pharmacol. 2005 Mar;45(3):257-64.
Abstract
Efficacy Data
 

    Journal Papers, Abstracts, and Commentaries

  A phase I study of abacavir (1592U89) alone and in combination with other antiretroviral
agents in infants and children with human immunodeficiency virus infection. AIDS Clinical
Trials Group 330 Team.
Kline MW, Blanchard S, Fletcher CV et al.
Pediatrics 1999; 103(4): e47.
Abstract

     Conference Reports, Abstracts and Posters

 

Highly active antiretroviral therapy including high dose abacavir reduces cerebrospinal fluid human
immunodeficiency virus (HIV) RNA and soluble tumor necrosis factor II receptor in children with HIV
encephalopathy
Saavedra-Lozano, S Madison, et al
(14IAC)
 Abstract

Antiretroviral efficacy and tolerability of Abacavir (ABC) based regimens in a clinical cohort
of HIV-infected children
F Hoffmann, T Niehues, B Buchholz, et al
 (14IAC)
Abstract
Adherence
 

     Conference Reports, Abstracts and Posters

  Adherence and acceptability of once daily lamivudine and abacavir in HIV-1
infected children.
LeProvost M., Flynn J., Green H., Gibb D.M., et al
 (3rd IAS)
 Abstract
Salvage Therapy
 

    Journal Papers, Abstracts, and Commentaries
 
  Salvage Therapy With Abacavir and Other Reverse Transcriptase Inhibitors for Human
Immunodeficiency-Associated Encephalopathy.
 Saavedra-Lozano J, Ramos JT, Navarro ML, et al 
Pediatr Infect Dis J. 2006 Dec;25(12):1142-1152.
Abstract
 

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Abacavir Pediatric Data