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Last Update:  July 04, 2008
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New and Noteworthy
     

July 2008
 
June 2008
 

General Reports
       

           Internet Documents
 
  FULL TEXT DOCUMENT
Toxoplasmosis Fact Sheet
CDC
September 23, 2003
Fact Sheet

          Journal Papers, Abstracts, and Commentaries

 
The Use of Donor and Recipient Screening for Toxoplasma in the Era of Universal Trimethoprim
Sulfamethoxazole Prophylaxis.

Gourishankar S, Doucette K, Fenton J, et al  

Transplantation
. 2008 Apr 15;85(7):980-985
Abstract
 
Higher perceived dominance in Toxoplasma infected men - a new evidence for role of increased
level of testosterone in toxoplasmosis-associated changes in human behavior.

Hodkova H, Kolbekova P, Skallova A, et al

Neuro Endocrinol Lett. 2007 Apr 15;28(2)
Abstract
 
Is there any relationship between toxoplasma infection and reactive arthritis?
Sert M, Ozbek S, Paydas S, Yaman A

J Postgrad Med.
2007 Jan-Mar;53(1):14-6.
Abstract
 
FULL-TEXT ARTICLE
Toxoplasma MIC2 Is a Major Determinant of Invasion and Virulence.
Huynh MH, Carruthers VB. 

PLoS Pathog.
2006 Aug 18;2(8)
Paper
 
Body height, body mass index, waist-hip ratio, fluctuating asymmetry and second
to fourth digit ratio in subjects with latent toxoplasmosis.
Flegr J, Hruskova M, Hodny Z, et al 
Parasitology. 2005 Jun;130(Pt 6):621-8.
Abstract
 
Maternal exposure to toxoplasmosis and risk of schizophrenia in adult offspring.
Brown AS, Schaefer CA, Quesenberry CP, et al 
Am J Psychiatry. 2005 Apr;162(4):767-73.
Abstract
 
Toxoplasma gondii infection in patients with hematological malignancies.
Pagano L, Trape G, Putzulu R, et al 
Ann Hematol. 2004 Sep;83(9):592-5.
Abstract
 
Toxoplasma gondii infection in patients with hematological malignancies.
Pagano L, Trape G, Putzulu R, et al 
Ann Hematol. 2004 Jul 3
Abstract
 

Pregnancy as a risk factor for acute toxoplasmosis seroconversion.
Avelino MM, Campos D, de Parada Jdo C, de Castro AM.

Eur J Obstet Gynecol Reprod Biol 2003 May 1;108(1):19-24
Abstract

Cerebral Toxoplasmosis.
Nath A, Sinai AP.
Curr Treat Options Neurol 2003 Jan;5(1):3-12
Abstract

Prevalence and predictors of Toxoplasma seropositivity in women with and at risk for
human immunodeficiency virus infection.
Falusi O, French AL, Seaberg EC, et al

Clin Infect Dis
2002 Dec 1;35(11):1414-7
Abstract
 
Incidence and determinants of bacterial infections in HIV-positive patients receiving anti-
Pneumocystis carinii/Toxoplasma gondii primary prophylaxis within a randomized clinical
trial.
Murri R, Ammassari A, Pezzotti P, et al.
 
J Acquir Immune Defic Syndr 2001 May 1;27(1):49-55
Abstract
 
Toxoplasma gondii antibody in HIV-infected persons.
Sukthana Y, Chintana T, Lekkla A.
J
 Med Assoc Thai 2000 Jun;83(6):681-4
Abstract

 

        Conference Reports, Abstracts, and Posters

  Immune Recovery under HAART is Associated with Restoration of Lymphocyte
Proliferation and  Gamma-Interferon Production in Presence of Toxoplasma gondii
Antigens

(41 ICAAC)

Abstract

Pathogenesis
 

          Journal Papers, Abstracts, and Commentaries

  Pathogenesis of toxoplasmosis.
Bhopale GM.
Comp Immunol Microbiol Infect Dis 2003 Jul;26(4):213-22
Abstract
 
  Immunopathogenesis of Cerebral Toxoplasmosis.
Suzuki Y.

J Infect Dis
2002 Dec 1;186 Suppl 2:S234-S240
Abstract
 

Case Studies/Literature Reviews
       

          Journal Papers, Abstracts, and Commentaries

 
Toxoplasmosis with hemophagocytic syndrome after bone marrow transplantation:
diagnosis at autopsy.
Duband S, Cornillon J, Tavernier E, et al 

Transpl Infect Dis.
2008 Apr 1
Abstract
 
FULL-TEXT ARTICLE
Toxoplasmic hepatitis in an immunocompetent patient.
Doğan N, Kabukçuoğlu S, Vardarelı E.
Turkiye Parazitol Derg. 2007;31(4):260-263
Paper

 
Severe Toxoplasma gondii I/III recombinant genotype encephalitis in a HIV patient.
Genot S, Franck J, Forel JM, et al

J Clin Microbiol.
2007 Jul 18;
Abstract
 
Transmission of toxoplasmosis in two renal allograft recipients receiving an organ from the
same donor.
Rogers NM, Peh CA, Faull R, et al  

Transpl Infect Dis.
2007 Jul 1;
Abstract
 
Intraglandular toxoplasmosis of the parotid gland pre- or postoperative diagnosis?
Hadi U, Rameh C.
Am J Otolaryngol. 2007 May-Jun;28(3):201-4.
Abstract
 
FULL TEXT ARTICLE
Disseminated toxoplasmosis presenting as sepsis in two AIDS patients.
Barbosa CJ, Molina RJ, Souza MB, et al 

Rev Inst Med Trop Sao Paulo
. 2007 Apr;49(2):113-116.
Paper
 
Cerebral toxoplasmosis in an allogeneic peripheral stem cell transplant recipient: case report
and review of literature.

Cibickova L, Horacek J, Prasil P, et al 
Transpl Infect Dis. 2007 Apr 11;
Abstract
 
Toxoplasma gondii pneumonia in immunocompetent subjects: case report and review.
Leal FE, Cavazzana CL, de Andrade HF Jr, et al  
Clin Infect Dis.
2007 Mar 15;44(6):e62-6

Abstract
 
Hemophagocytic syndrome associated with extracerebral toxoplasmosis in an
HIV-infected patient.
Guillaume MP, Driessens N, Libert M, et al
 
Eur J Intern Med.
2006 Nov;17(7):503-4.
Abstract
 
Fulminant toxoplasmosis causing fatal pneumonitis and myocarditis.
Eza D, Lucas S.
HIV Med. 2006 Sep;7(6):415-420.
Abstract
 
Toxoplasmosis-associated hemophagocytic syndrome in renal transplantation.
Segall L, Moal MC, Doucet L, Kergoat N, et al; 

Transpl Int
. 2006 Jan;19(1):78-80.
Abstract
 
AIDS-related cerebral toxoplasmosis with hyperintense foci on T1-weighted MR images:
A case report.

Maeda T, Fujii T, Matsumura T, et al

J Infect. 2006 Jan 25;
Abstract

Toxoplasmic meningoencephalitis in an immunocompetent host.
Kaushik RM, Mahajan SK, Sharma A, et al

Trans R Soc Trop Med Hyg.
2005 Aug 16;
Abstract
 
Recurrent secondary frosted branch angiitis after toxoplasmosis vasculitis.
Oh J, Huh K, Kim SW.
Acta Ophthalmol Scand. 2005 Feb;83(1):115-7
Abstract

Transient hypogonadotrophic hypogonadism in males with acute toxoplasmosis:
 suppressive effect of interleukin-1{beta} on the secretion of GnRH.
Oktenli C, Doganci L, Ozgurtas T, et al 

Hum Reprod.
2004 Feb 27
Abstract

Toxoplasmic myositis as a presenting manifestation of idiopathic CD4 lymphocytopenia.
Plonquet A, Bassez G, Authier FJ, et al. 

Muscle Nerve
2003 Jun;27(6):761-765
Abstract

Gastric toxoplasmosis in a patient with acquired immunodeficiency syndrome. A case
report and review of the literature.
Ganji M, Tan A, Maitar MI, et al.
Arch Pathol Lab Med 2003 Jun;127(6):732-4
Abstract
 
Toxoplasmosis following allogeneic hematopoietic stem cell transplantation.
Martino R, Cordonnier C.
 
Bone Marrow Transplant
2003 Apr;31(7):617-8
Abstract

Two case reports of pituitary adenoma associated with Toxoplasma gondii infection.
Zhang X, Li Q, Hu P, et a
l.
J Clin Pathol 2002 Dec;55(12):965-6
Abstract

Acute iridocyclitis in a patient with AIDS diagnosed as toxoplasmosis by PCR.
Cano-Parra JL, Diaz-LLopis ML, et al.
Ocul Immunol Inflamm 2000 Jun;8(2):127-30
Abstract

 

Prevention   
Prophylaxis Vaccine    

Prophylaxis

     Journal Papers, Abstracts, and Commentaries

 
Discontinuation of primary and secondary Toxoplasma gondii prophylaxis is safe in HIV-
infected patients after immunological restoration with highly active antiretroviral therapy:
results of an open, randomized, multicenter clinical trial.
Miro JM, Lopez JC, Podzamczer D, ry al
Clin Infect Dis. 2006 Jul 1;43(1):79-89.
Abstract

Treating Opportunistic Infections Among HIV-Infected Adults and Adolescents:
Recommendations from CDC, the National Institutes of Health, and the HIV
Medicine Association/Infectious Diseases Society of America
MMWR Dec 17, 2004 / Vol. 53 / No. RR--1
Paper
 

  Prophylaxis with trimethoprim-sulfamethoxazole for human immunodeficiency virus-infected
patients: impact on risk for infectious diseases.
Dworkin MS, Williamson J, Jones JL, et al.
Clin Infect Dis 2001 Aug 1;33(3):393-8
Abstract

Vaccine

    Journal Papers, Abstracts, and Commentaries

  Development of a vaccine for toxoplasmosis: current status.
Bhopale GM.
Microbes Infect 2003 Apr;5(5):457-62
Abstract

Diagnosis/Monitoring
       

   Journal Papers, Abstracts, and Commentaries

 
Use of the serum reactivity against Toxoplasma gondii excreted-secreted antigens in cerebral toxoplasmosis
diagnosis in human immunodeficiency virus-infected patients.

Meira CS, Costa-Silva TA, Vidal JE, et al 
J Med Microbiol. 2008 Jul;57(Pt 7):845-50.
Abstract
 
Reverse ELISA using monoclonal antibodies against SAG1-related sequence, SAG2A and p97 antigens from
Toxoplasma gondii for detection of specific IgG, IgM and IgA antibodies in human sera.

Carvalho FR, Silva DA, Cunha-Júnior JP, et al 
Clin Vaccine Immunol. 2008 Jun 18.
Abstract
 
A prospective study of diagnosis of Toxoplasma gondii infection after bone marrow transplantation.
Edvinsson B, Lundquist J, Ljungman P, et al 
A
PMIS.
2008 May;116(5):345-51

Abstract
 
Evaluation of the Korean isolate-1 tachyzoite antigen for serodiagnosis of toxoplasmosis.
Shin EH, Kim DH, Lin A, et al
Korean J Parasitol. 2008 Mar;46(1):45-8.
Abstract
 
A new combined flow-cytometry-based assay reveals excellent activity against Toxoplasma
gondii and low toxicity of new bisphosphonates in vitro and in vivo.
Shubar HM, Mayer JP, Hopfenmüller W, Liesenfeld O.
J Antimicrob Chemother. 2008 Feb 19
Abstract
 
Recommendation for diagnostics and therapy of toxoplasmosis in persons with HIV infection
Machala L, Kodym P, Rozsypal H, et al
Klin Mikrobiol Infekc Lek. 2007 Dec;13(6):248-52.
Abstract
 
Toxoplasma gondii: Enzyme-linked immunosorbent assay using different fragments of
recombinant microneme protein 1 (MIC1) for detection of immunoglobulin G antibodies.
Holec L, Gąsior A, Brillowska-Dąbrowska A, Kur J.
 
Exp Parasitol.
2008 Jan 18
Abstract
 
Detection of the presence of antibodies against Toxoplasma gondii in human colostrum by
Raman spectroscopy and principal component analysis.
Araujo-Andrade C, Pichardo-Molina JL, Barbosa-Sabanero G, et al
J Biomed Opt. 2007 May-Jun;12(3):034006.
Abstract
 
Evaluation of a real-time PCR assay based on the repetitive B1 gene for the detection of
Toxoplasma gondii in human peripheral blood.

Kompalic-Cristo A, Frotta C, Suarez-Mutis M, et al

 Parasitol Res. 2007 Mar 25;
Abstract
 
Real-time PCR in the diagnosis of toxoplasmosis: the way to standardisation?
Maubon D, Brenier-Pinchart MP, Fricker-Hidalgo H, Pelloux H.
Pathol Biol (Paris). 2007 Feb 13;
Abstract
 
Evaluation of a commercial IgE ELISA in comparison with IgA and IgM ELISAs, IgG avidity
assay and complement fixation for the diagnosis of acute toxoplasmosis.
Kodym P, Machala L, Rohacova H, et al 

Clin Microbiol Infect.
2007 Jan;13(1):40-7.
Abstract
 
Analysis of the utility of diffusion-weighted MRI and apparent diffusion coefficient values in
distinguishing central nervous system toxoplasmosis from lymphoma.
Schroeder PC, Post MJ, Oschatz E, et al
 
Neuroradiology.
2006 Oct;48(10):715-20.
Abstract
 
Association of ocular toxoplasmosis with type I Toxoplasma gondii strains: direct genotyping
from peripheral blood samples.
Switaj K, Master A, Borkowski PK, et al 

J Clin Microbiol.
2006 Sep 27;

Abstract
 
Usefulness of Toxoplasma gondii recombinant antigens (GRA1, GRA7 and SAG1) in an
immunoglobulin G avidity test for the serodiagnosis of toxoplasmosis.
Pietkiewicz H, Hiszczynska-Sawicka E, et al  
Parasitol Res. 2006 Aug 8;
Abstract
 
Third-generation optical coherence tomography findings in punctate retinal toxoplasmosis.
Orefice JL, Costa RA, Campos W, et a  
Am J Ophthalmol. 2006 Sep;142(3):503-5
Abstract
 
Diagnosis of pulmonary infection with Toxoplasma gondii in immunocompromised
HIV-positive  patients by real-time PCR.
Petersen E, Edvinsson B, Lundgren B, et a' 
Eur J Clin Microbiol Infect Dis. 2006 Jun;25(6):401-4.
Abstract
 
Fluorescein and indocyanine green angiography in ocular toxoplasmosis.
Atmaca LS, Simsek T, Atmaca Sonmez P, Sonmez K. 

Graefes Arch Clin Exp Ophthalmol.
2006 May 4
Abstract
 
Comparison between two amplification sets for molecular diagnosis of toxoplasmosis by
real-time PCR.

Cassaing S, Bessieres MH, Berry A, et al
J Clin Microbiol. 2006 Mar;44(3):720-4.
Abstract|
 
Timely diagnosis of disseminated toxoplasmosis by sputum examination.
Laibe S, Ranque S, Curtillet C, Faraut F, et al
 
J Clin Microbiol. 2006 Feb;44(2):646-8.
Abstract
 
Comparison between two amplification sets for molecular diagnosis of toxoplasmosis
by real-time PCR.
Cassaing S, Bessieres MH, Berry A, et al   
J Clin Microbiol. 2006 Mar;44(3):720-4
Abstract
 
Recent trends in molecular diagnostics for Toxoplasma gondii infections.
Switaj K, Master A, Skrzypczak M, Zaborowski P.
Clin Microbiol Infect. 2005 Mar;11(3):170-6.
Abstract
 
Evaluation of a Real-time PCR-based assay using the lightcycler system for detection
of Toxoplasma gondii bradyzoite genes in blood specimens from patients with toxoplasmic
retinochoroiditis.

Contini C, Seraceni S, Cultrera R, Incorvaia C, et al
Int J Parasitol. 2005 Mar;35(3):275-83.
Abstract
 
Real-time quantitative PCR for toxoplasmosis diagnosis
Ordinaire I, Simon A, Frealle E,
Ann Biol Clin (Paris). 2005 Jan-Feb;63(1):67-73.
Abstract
 
Detection of anti-Toxoplasma gondii IgG, IgM and IgA immunoglobulins in the serum,
cerebrospinal fluid and saliva of patients with acquired immunodeficiency syndrome and
neurotoxoplasmosis.
Borges AS, Figueiredo JF.
 
Arq Neuropsiquiatr.
2004 Dec;62(4):1033-7.
Abstract
 
Performance of the Immunoglobulin G Avidity and Enzyme Immunoassay IgG/IgM
Screening Tests for Differentiation of the Clinical Spectrum of Toxoplasmosis.
Tanyuksel M, Guney C, Araz E, et al 
J Microbiol. 2004 Sep;42(3):211-5.
Abstract
 
Drug monitoring of pyrimethamine during maintenance therapy of toxoplasmic
encephalitis in patients with advanced HIV infection during HAART.
Langmann P, Schirmer D, Zilly M, Klinker H. 

Med Sci Monit.
2004 May;10(5):PI65-9.
Abstract
 
Diagnostic approaches to severe, atypical toxoplasmosis mimicking acute retinal
necrosis.
Moshfeghi DM, Dodds EM, et al 
Ophthalmology.
2004 Apr;111(4):716-25.
Abstract
 
Utility of ultrasonography in toxoplasmic uveitis
Santos Hercos BV, Muinos SJ, Casaroli-Marano RP.

Arch Soc Esp Oftalmol.
2004 Feb;79(2):59-66.
Abstract
 
Lack of technical specificity in the molecular diagnosis of toxoplasmosis.
Kompalic-Cristo A, Nogueira SA ,et al  
Trans R Soc Trop Med Hyg. 2004 Feb;98(2):92-5
Abstract
 
FULL-TEXT ARTICLE
Rapid diagnosis of toxoplasmosis
Reischl U, Bretagne S, Krüger D, et al.
BMC Infectious Diseases 2003, 3:7
Paper
 
Differentiation of toxoplasmosis and lymphoma in AIDS patients by using apparent
iffusion coefficients
.
Camacho DL, Smith JK, Castillo M. 
Am J Neuroradiol 2003 Apr;24(4):633-
Abstract

Optimization and Evaluation of a PCR Assay for Detecting Toxoplasmic Encephalitis in
Patients with AIDS.

Joseph P, Calderon MM, Gilman RH, et al.
J Clin Microbiol 2002 Dec;40(12):4499-4503
Abstract

Automated time-resolved immunofluorometric assay for Toxoplasma gondii-specific IgM
and IgA antibodies: study of more than 130,000 filter-paper blood-spot samples from
newborns.
Sorensen T, Spenter J, Jaliashvili I, et al
 
Clin Chem
2002 Nov;48(11):1981-6
Abstract

Diagnosis of toxoplasmic retinochoroiditis with atypical clinical features.
Fardeau C, Romand S, Rao NA,

Am J Ophthalmol
2002 Aug;134(2):196-203
Abstract

MRI features of toxoplasma encephalitis in the immunocompetent host: a report of
two cases.
Vastava PB, Pradhan S, Jha S, et al.
 
Neuroradiology
2002 Oct;44(10):834-8
Abstract

Molecular diagnosis of toxoplasmosis.
Bastien P.
Trans R Soc Trop Med Hyg 2002 Apr;96 Suppl 1:S205-15
Abstract
 
Immunoglobulin M (IgM)-glycoinositolphospholipid enzyme- linked immunosorbent assay:
an immunoenzymatic assay for discrimination between atients with acute toxoplasmosis
and those with persistent parasite-specific IgM antibodies.
Giraldo M, Portela RW, Snege M, Leser PG, et al.
J Clin Microbiol 2002 Apr;40(4):1400-5
Abstract
 
Detection by nested-PCR of Toxoplasma gondii in patients infected with human
immunodeficiency virus
Alonso R, Martinez E, Laynez P, et al
Med Clin (Barc) 2002 Mar 9;118(8):294-6
Abstract
 
Evaluation of the Immulite 2000 Toxoplasma quantitative IgG et Toxoplasma IgM for the
diagnosis of human toxoplasmosis
Dao A, Fortier B.
Ann Biol Clin (Paris) 2001 Mar-Apr;59(2):157-64
Abstract
 
Polymerase chain reaction for diagnosis of cerebral toxoplasmosis in cerebrospinal fluid in
HIV-positive patients.
Julander I, Martin C, Lappalainen M, et al

Scand J Infect Dis
2001;33(7):538-41
Abstract
 
Genotyping of Toxoplasma gondii strains from immunocompromised patients.
Honore S, Couvelard A, Garin YJ, et al.
Pathol Biol (Paris) 2000 Jul;48(6):541-7
Abstract

 

Clinical Management
       

   Journal Papers, Abstracts, and Commentaries

 
Recommendation for diagnostics and therapy of toxoplasmosis in persons with HIV infection
Machala L, Kodym P, Rozsypal H, et al
Klin Mikrobiol Infekc Lek. 2007 Dec;13(6):248-52.
Abstract
 
Toxoplasma meningoencephalitis in HIV-seronegative patients: clinical patterns,
imaging features and treatment outcome.

Pradhan S, Yadav R, Mishra VN.  

Trans R Soc Trop Med Hyg
. 2006 Sep 27;
Abstract
 
Management of toxoplasmic encephalitis in HIV-infected adults (with an emphasis on resource-
poor settings).
Dedicoat M, Livesley N.
Cochrane Database Syst Rev. 2006 Jul 19
Abstract
 
Atypical toxoplasmic manifestation after discontinuation of maintenance therapy in a
human immunodeficiency virus type 1-infected patient with immune recovery.
Ghosn J, Paris L, Ajzenberg D,et al 

Clin Infect Dis.
2003 Oct 1;37(7)
Abstract

Discontinuation of secondary prophylaxis against disseminated Mycobacterium avium
complex infection and toxoplasmic encephalitis.
Zeller V, Truffot C, Agher R, et al.

Clin Infect Dis 2002 Mar 1;34(5):662-7
Abstract

Reactivation of retinal toxoplasmosis despite evidence of immune response to highly
active antiretroviral therapy.
Stout JE, Lai JC, Giner J, Hamilton CD.

Clin Infect Dis
2002 Aug 15;35(4):e37-9
Abstract

 

HIV Systemic Studies [Links to HIV Web]
Cerebral Toxoplasmosis Ocular Toxoplasmosis Gastric Toxoplasmosis  


Treatment/Prevention Guidelines
       

United States

         Journal Papers, Abstracts, and Commentaries

  Treating Opportunistic Infections Among HIV-Infected Adults and Adolescents:
Recommendations from CDC, the National Institutes of Health, and the HIV
Medicine Association/Infectious Diseases Society of America
MMWR Dec 17, 2004 / Vol. 53 / No. RR--1
Paper
 
 


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