Medical Advocates

Cryptosporidiosis
l   Drugs

Antiretrovirals    
Mebendazole          

Nitazoxanide   
Paromomycin
Rifabutin
Rifaximin


 
 

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Last Update:  February 16, 2011
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General Reports
       

        Journal Papers, Abstracts, and Commentaries
 
  New drugs and treatment for cryptosporidiosis.
Smith HV, Corcoran GD. 

Curr Opin Infect Dis.
2004 Dec;17(6):557-64.

Abstract

Antiretrovirals
       

         Journal Papers, Abstracts, and Commentaries 
 
Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin,
on the excystation, invasion and in vitro development of Cryptosporidium parvum.

Hommer V, Eichholz J, Petry F.
J Antimicrob Chemother. 2003 Jul 29
Abstract

Mebendazole
       

       Journal Papers, Abstracts, and Commentaries
 
  Effectiveness and safety of mebendazole compared to nitazoxanide in the treatment of
Giardia lamblia in children
Rodriguez-Garcia R, Rodriguez-Guzman LM, Cruz del Castillo AH.
Rev Gastroenterol Mex 1999 Jul-Sep;64(3):122-6
Abstract
 

Nitazoxanide    
       

       Journal Papers, Abstracts, and Commentaries
 
 
Nitazoxanide in the treatment of acquired immune deficiency syndrome-related
cryptosporidiosis: results of the United States compassionate use program in 365 patients
Rossignol JF
.
Aliment Pharmacol Ther.
2006 Sep 1;24(5):887-94
Abstract
 
Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis:
a randomised controlled trial.
Amadi B, Mwiya M, Musuku J, et al.

Lancet 2002 Nov 2;360(9343):1375-1380
Abstract
 
Nitazoxanide pharmacokinetics and tolerability in man during 7 days dosing with 0.5 g
and 1 g b.i.
d.
Stockis A, De Bruyn S, Gengler C, Rosillon D.
Int J Clin Pharmacol Ther 2002 May;40(5):221-7

Abstract
 
Treatment of diarrhea caused by Cryptosporidium parvum: a prospective randomized,
double-blind, placebo-controlled study of Nitazoxanide.
Rossignol JF, Ayoub A, Ayers MS.
J Infect Dis 2001 Jul 1;184(1):103-6

Abstract
 
A double-'blind' placebo-controlled study of nitazoxanide in the treatment of cryptosporidial
diarrhoea in AIDS patients in Mexico.
Rossignol JF, Hidalgo H, Feregrino M.
Trans R Soc Trop Med Hyg 1998 Nov-Dec;92(6):663-6
Abstract
 
Nitazoxanide in the treatment of cryptosporidial diarrhea and other intestinal parasitic
infections associated with acquired immunodeficiency syndrome in tropical Africa.
Doumbo O, Rossignol JF, Pichard E, et al.
Am J Trop Med Hyg 1997 Jun;56(6):637-9
Abstract
 

Paromomycin
       

        Journal Papers, Abstracts, and Commentaries
 
 
Pulmonary cryptosporidiosis in an AIDS patient: successful treatment with paromomycin
plus azithromycin.
Palmieri F, Cicalini S, Froio N, et al
Int J STD AIDS. 2005 Jul;16(7):515-7.
bstract

Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin,
on the excystation, invasion and in vitro development of Cryptosporidium parvum.

Hommer V, Eichholz J, Petry F.
J Antimicrob Chemother. 2003 Jul 29
Abstract


Rifabutin
       

        Journal Papers, Abstracts, and Commentaries
 
  Rifabutin but not clarithromycin prevents cryptosporidiosis in persons with advanced
HIV infection. 
Fichtenbaum CJ, Zackin R, Feinberg J et al.
AIDS 2000 Dec  22;14(18):2889-93
Abstract

Rifaximin
       

  Journal Papers, Abstracts, and Commentaries
 
  Intestinal protozoa in HIV-infected patients: effect of rifaximin in
Cryptosporidiumparvum and Blastocystis hominis infections. .
Amenta M, Dalle Nogare ER, Colomba C

J Chemother 1999 Oct;11(5):391-5
Abstract


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