Medical Advocates
Cryptococcosis
  Drugs
 
Aceyazolamide
Albaconazole
Amphotericin B 
Atorvastatin
 Fluconazole
Flucytosine
 IFN-gamma  
HAART/ART
IL-12   
Isavuconazole		 Itraconazole
 Posaconazole
 Saquinavir
Sertraline
 Voriconazole   
Azoles: General Reports
Antifungals: General Reports
Antiretrovirals: General Reports   
 

 
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Last Update:  May 03, 2017
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Aceyazolamide
       

     Journal Papers, Abstracts, and Commentaries

  A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment
of elevated intracranial pressure in cryptococcal meningitis.
Newton PN, Thai le H, Tip NQ
Clin Infect Dis 2002 Sep 15;35(6):769-72
 Abstract		  
Albaconazole
       

        Journal Papers, Abstracts, and Commentaries

  In Vitro and In Vivo Efficacies of the New Triazole Albaconazole against Cryptococcus
neoformans.
Miller JL, Schell WA, Wills EA, et al  
Antimicrob Agents Chemother. 2004 Feb;48(2):384-7.
Abstract
Amphotericin B
       

        Journal Papers, Abstracts, and Commentaries

 
"Time-to-Amphotericin B" in Cryptococcal Meningitis in a European Low-Prevalence Setting: Analysis of Diagnostic Delays.
Katchanov J, von Kleist M, Arastéh K, Stocker H.
QJM. 2014 Apr 10.
 Abstract

Comparison of 2 Doses of Liposomal Amphotericin B and Conventional Amphotericin B
Deoxycholate for Treatment of AIDS-Associated Acute Cryptococcal Meningitis:
A Randomized, Double-Blind Clinical Trial of Efficacy and Safety.
Hamill RJ, Sobel JD, El-Sadr W,  et al
Clin Infect Dis. 2010 Jun 10
 Abstract
 
Atorvastatin
       

        Journal Papers, Abstracts, and Commentaries

  Atorvastatin as a promising anticryptococcal agent.
Ribeiro NQ, Costa MC, Magalhães TFF, et al  
Int J Antimicrob Agents. 2017 Apr 24.
Abstract
Fluconazole
       

        Journal Papers, Abstracts, and Commentaries

 
A subdose of fluconazole alters the virulence of Cryptococcus gattii during murine cryptococcosis and modulates type I interferon expression.
Fontes AC, Bretas Oliveira D, et al
 Med Mycol. 2016 Aug 2.
 Abstract

FULL-TEXT ARTICLE
Increasing trend of fluconazole-non-susceptible Cryptococcus neoformans in patients with invasive cryptococcosis: a 12-year longitudinal study.
Chen YC, Chang TY, Liu JW,  et al 
BMC Infect Dis. 2015 Jul 22;15:277.
 Paper
 
Flucytosine
       

        Journal Papers, Abstracts, and Commentaries

 
Oral versus intravenous flucytosine in patients with HIV-associated cryptococcal meningitis.
Brouwer AE, van Kan HJ, Johnson E, et al
Antimicrob Agents Chemother. 2006 Dec 28;
Abstract
HAART/ART
       

        Journal Papers, Abstracts, and Commentaries

 
Indinavir-treated Cryptococcus neoformans promotes an efficient antifungal immune
response in immunosuppressed hosts.
Pericolini E, Cenci E, Monari C, et al  
Med Mycol. 2006 Mar;44(2):119-26.
 Abstract
IFN-gamma
       

        Journal Papers, Abstracts, and Commentaries

 
Recombinant Interferon- gamma 1b as Adjunctive Therapy for AIDS-Related Acute
Cryptococcal Meningitis.
Pappas PG, Bustamante B, Ticona E, et al 
J Infect Dis. 2004 Jun 15;189(12):2185-91.
 Abstract
IL-12
       

        Journal Papers, Abstracts, and Commentaries

  Induction of Interleukin-12 and Gamma Interferon Requires Tumor Necrosis Factor
Alpha for Protective T1-Cell-Mediated Immunity to Pulmonary Cryptococcus neoformans
Infection.
Herring AC, Lee J, McDonald RA, Toews GB, Huffnagle GB.
Infect Immun 2002 Jun;70(6):2959-64
 Abstract
Isavuconazole
       

        Journal Papers, Abstracts, and Commentaries

  Evaluation of Etest Method for Determining Isavuconazole MICs Against Cryptococcus gattii a
nd Cryptococcus neoformans.
Thompson GR 3rd, Fothergill AW, Wiederhold NP, et al   
Antimicrob Agents Chemother. 2008 Jun 16.
Abstract		  
Itraconazole
       

        Journal Papers, Abstracts, and Commentaries

  Comparison of in vitro Antifungal Activities of Amphotericin B Lipid Complex with
Itraconazole against 708 Clinical Yeast Isolates and Opportunistic Moulds Determined
by National Committee for Clinical Laboratory Standards Methods M27-A and M38-P.
Carrillo-Munoz AJ, Ruesga M, Brio S, Del Valle O, et al
 Chemotherapy 2002 Dec;48(5):224-231
 Abstract		  
Posaconazole
       
        Journal Papers, Abstracts, and Commentaries
 
  Posaconazole and amphotericin B combination therapy against Cryptococcus
neoformans infection.
Barchiesi F, Spreghini E, Schimizzi AM, et al  
Antimicrob Agents Chemother. 2004 Sep;48(9):3312-6.
Abstract
Saquinavir
       
        Journal Papers, Abstracts, and Commentaries
 
  Interaction between saquinavir and antimycotic drugs on C. albicans and C.
neoformans strains.
Casolari C, Rossi T, Baggio G, Coppi A,
Pharmacol Res. 2004 Dec;50(6):605-10.
 Abstract
Sertraline
       
        Journal Papers, Abstracts, and Commentaries
 
  IThe Antidepressant Sertraline Provides a Promising Therapeutic Option for Neurotropic
Cryptococcal Infections.
Zhai B, Wu C, Wang L, et al
Antimicrob Agents Chemother. 2012 Apr 16
 Abstract
Voriconazole
       
        Journal Papers, Abstracts, and Commentaries
 
 
Long-Term Efficacy and Safety of TDM-Assisted Combination of Voriconazole plus Efavirenz in an
AIDS Patient with Cryptococcosis and Liver Cirrhosis (May).
Carbonara S, Regazzi M, Ciracì E, .et al
Ann Pharmacother. 2009 Apr 21.
Abstract
 
Azoles: General Reports
       
        Journal Papers, Abstracts, and Commentaries
 
  Prevention of cryptococcosis in HIV-infected patients with limited access to highly active
antiretroviral therapy: evidence for primary azole prophylaxis.
Caney P, Stephens D, Rimland D.
HIV Med. 2005 Jul;6(4):253-9
 Abstract		  
Antifungals: General Reports
       
        Journal Papers, Abstracts, and Commentaries
 
  Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV.
Chang L, Phipps W, Kennedy G, Rutherford G. 
Cochrane Database Syst Rev. 2005 Jul 20;(3):CD004773. 
Abstract		  
Antiretrovirals: General Reports
       
        Journal Papers, Abstracts, and Commentaries
 
  Approaches to antifungal therapies and their effectiveness among patients with cryptococcosis.
 Bratton EW, El Husseini N, Chastain CA, et al
Antimicrob Agents Chemother. 2013 Mar
Abstract

Optimal timing for antiretroviral therapy initiation in patients with HIV infection and concurrent cryptococcal meningitis.
Njei B, Kongnyuy EJ, Kumar S, et al
Cochrane Database Syst Rev. 2013 Feb 28;2:CD009012.
 Abstract

  

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