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HIV Infection/Disease
  Hepatic Disorders
New and Noteworthy           Liver Transplantation
General Reports                  Hepatocellular Carcinoma
 Cirrhosis                              HIV/HCV 
Gilbert's Disease                  Cholangiopathy
 Hyperbilirubinemia              Steatohepatitis
Hepatic Failure      
Hepatic Encephalopathy
Hepatic Toxoplasmosis
Hepatic Steatosis
Hepatoportal Stenosis
 Fatty Liver Disease
 Liver Fibrosis
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Last Update:  January 20, 2012  
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New and Noteworthy
     
January 2012
 
General Reports
       
           Journal Papers, Abstracts, and Commentaries
 
 
The association of HIV viral load with indirect markers of liver injury.
Forrester JE, Rhee MS, McGovern BH, et al
J Viral Hepat. 2012 Feb;19(2):e202-11.
 Abstract

Liver disease, HIV and aging.
Falade-Nwulia O, Thio CL.
Sex Health. 2011 Nov;8(4):512-20.
 Abstract

HIV Variability in the Liver and Evidence of Possible Compartmentalization.
Blackard JT, Ma G, Martin CM,  et al
 AIDS Res Hum Retroviruses. 2011 Oct;27(10):1117-26.
Abstract

Influence of antiretroviral therapy on liver disease.
Kovari H, Weber R.
 Curr Opin HIV AIDS. 2011 Apr 20
 Abstract

Increasing burden of liver disease in patients with HIV infection.
Joshi D, O'Grady J, Dieterich D, et al
Lancet. 2011 Apr 2;377(9772):1198-209.
 Abstract

Liver Disease in the HIV-Infected Individual.
Price JC, Thio CL.
Clin Gastroenterol Hepatol. 2010 Sep 16
 Abstract

An unusual pathogen for a liver abscess in a human immunodeficiency
virus-infected individual.
Sayana S, Ricaurte JC, Khanlou H.
Am J Med Sci. 2010 Mar;339(3):290-1.
 Abstract

Prevalence and Factors Associated with Liver Enzyme Abnormalities among HIV-Infected.
Crum-Cianflone N, Collins G, Medina S, et al
Clin Gastroenterol Hepatol. 2009 Oct 1
 Abstract

FULL-TEXT ARTICLE
 PPAR and Liver Injury in HIV-Infected Patients.
Lemoine M, Capeau J, Serfaty L.
 PPAR Res. 2009;2009:906167.
Paper

The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala,
Uganda.
Ocama P, Katwere M, Piloya T,et al
 Afr Health Sci. 2008 Mar;8(1):8-12.
 Abstract
 
Liver Complications Have Reached a Plateau as Cause of Hospital Admission and Death in
HIV Patients in Madrid.
Núñez-Fernández C, Martín-Carbonero L, Valencia ME, et al
AIDS Res Hum Retroviruses. 2009 Mar 25.
Abstract
 
Liver enlargement associated with opportunistic infections in patients with human
immunodeficiency virus infection.
Terzic D, Brmbolic B, Singer D, et al
J Gastrointestin Liver Dis. 2008 Dec;17(4):401-4
 Abstract
 
HAART and Liver: A discussion of hepatic disease in those living with HIV.
Cooper C, Adams PC.  
Can J Gastroenterol. 2008 Dec;22(12):973-5.
 Abstract
 
Management of hepatic complications in HIV-infected persons.
Sulkowski MS.
J Infect Dis. 2008 May 15;197
Abstract
 
The Prevalence and Risk Factors for Abnormal Liver Enzymes in HIV-Positive Patients without
Hepatitis B or C Coinfections.
Sterling RK, Chiu S, Snider K, Nixon D.
Dig Dis Sci. 2007 Oct 16;
 Abstract
 
HIV and Liver Diseases: Recent Clinical Advances.
Cengiz C, Park JS, Saraf N, Dieterich DT.  
Clin Liver Dis. 2005 Nov;9(4):647-66.
Abstract
 
Liver-related deaths in persons infected with the human immunodeficiency virus: the d:a:d
study.
[No authors listed]
Arch Intern Med. 2006 Aug 14;166(15):1632-41.
 Abstract

Liver involvement in secondary infections in HIV-infected patients
Shakhgil'dian VI, Kravchenko AV, Parkhomenko IuG, et al
Ter Arkh 2002;74(11):40-3
 Abstract
 

  
          Conference Reports, Abstracts, and Posters
 
 
Risk factors for advanced liver fibrosis in HIV-infected individuals: role of the metabolic syndrome
Blanco F, Barreiro P, Ryan P, et al
(Ninth International Congress on Drug Therapy in HIV Infection)
 Abstract
 
Surrogate markers for liver damage (i.e. how can we measure the extent of fibrosis and
disease without biopsy)
M Puoti
 (Ninth International Congress on Drug Therapy in HIV Infection)
PDF Abstract
 
Liver Disease of Unknown Etiology in HIV-infected Patients: Prevalence, Clinical Presentation,
and Putative Causes
P Barreiro, I Maida, L Martín-Carbonero, et al
(14 CROI)
 Abstract

POSTER
Exposure to ART and the Risk of Liver-related Death: Is there an Association? Results from
the D:A:D Study
R Weber, C Sabin, N Friis-Møller, et al
(13 CROI)
PDF Poster     Abstract
 
  Estimated Prevalence of Significant Liver Disease among 4052 HIV-infected Adults with and
without Chronic Hepatitis B and C
M S. Sulkowski, S Mehta,  R Montes De Oca, et al
(13 CROI)
 Abstract
Cirrhosis
       

           Journal Papers, Abstracts, and Commentaries

 
From nonalcoholic fatty liver to nonalcoholic steatohepatitis and cirrhosis in HIV-infected patients:
diagnosis and management.
Lemoine M, Serfaty L, Capeau J.
 Curr Opin Infect Dis. 2012 Feb;25(1):10-6..
 Abstract

Survival of HIV-infected patients with compensated liver cirrhosis.
Tuma P, Jarrin I, Del Amo J, Vispo E,  et al
AIDS. 2010 Feb 11.
 Abstract

Liver cirrhosis in HIV-infected patients: prevalence, aetiology and clinical outcome.
Castellares C, Barreiro P, Martín-Carbonero L, et al
J Viral Hepat. 2008 Mar;15(3):165-72.
Abstract

  
Gilbert's Disease
       

           Conference Reports, Abstracts, and Posters
 
  POSTER
Gilbert’s Disease and Atazanavir: From Phenotype to UDP-glucuronosyltransferease Haplotype
T Lankisch, Gehrens, U Moebius
(14 CROI)
 PDF Poster     Abstract
Hyperbilirubinemia
 
        Journal Papers, Abstracts, and Commentaries
 
 
Practical preclinical model for assessing the potential for unconjugated hyperbilirubinemia
produced by human immunodeficiency virus protease inhibitors.
Kempf DJ, Waring JF, Morfitt DC, et al 
Antimicrob Agents Chemother. 2006 Feb;50(2):762-4.
 Abstract

Hyperbilirubinemia in the setting of antiviral therapy.
 Korenblat KM, Berk PD.  
Clin Gastroenterol Hepatol. 2005 Apr;3(4):303-10.
 Abstract

 
Hepatic Failure
       
        Journal Papers, Abstracts, and Commentaries
 
 

 
Orthotopic liver transplantation in patients with human immunodeficiency virus and
end-stage liver disease.
 Neff GW, Bonham A, Tzakis AG
 Liver Transpl
Abstract

Acute hepatic failure and lactate acidosis associated with antiretroviral treatment for HIV.
Koch RO, Graziadei IW, Zangerle R, et al 
Wien Klin Wochenschr 2003 Feb 28;115(3-4):135-40
 Abstract
Hepatic Encephalopathy
       

           Journal Papers, Abstracts, and Commentaries

 
Hepatic encephalopathy as an unusual late complication of transjugular intrahepatic
portosystemic shunt insertion for non-cirrhotic portal hypertension caused by nodular
regenerative hyperplasia in an HIV-positive patient on highly active antiretroviral therapy.
Ding A, Lee A, Callender M, et al
 Int J STD AIDS. 2010 Jan;21(1):71-2
 Abstract

Hepatic encephalopathy in primary human immunodeficiency virus type 1 (HIV-1)
infection.
Kobesso H, Matsushita A, Takahashi K
Intern Med 2002 Nov;41(11):1069-72
 Abstract

  
Hepatic Toxoplasmosis
       
         Journal Papers, Abstracts, and Commentaries
 
  Gastric toxoplasmosis in a patient with acquired immunodeficiency syndrome.
A case report and review of the literature.
Ganji M, Tan A, Maitar MI, et al.
Arch Pathol Lab Med 2003 Jun;127(6):732-4
 Abstract		  
Hepatic Steatosis
       
           Journal Papers, Abstracts, and Commentaries
 
 
Review: Hepatic Steatosis and HIV Infection.
Ristig M, Drechsler H, Powderly WG.   
AIDS Patient Care STDS. 2005 Jun;19(6):356-65.
Abstract
 
Hepatic steatosis: an emerging cause of cirrhosis in HIV patients.
Loulergue P, Callard P, Bonnard P, Pialoux G.
Pathol Biol (Paris). 2006 Oct 4
 Abstract
 
Hepatic steatosis is associated with fibrosis, nucleoside analogue use, and
hepatitis C virus genotype 3 infection in HIV-seropositive patients.
McGovern BH, Ditelberg JS, Taylor LE,
Clin Infect Dis. 2006 Aug 1;43(3):365-72.
 Abstract
 
Liver steatosis in HIV-infected patients.
Piroth L.
AIDS Rev. 2005 Oct-Dec;7(4):197-209.
 Abstract
 
Mitochondrial injury in the pathogenesis of antiretroviral-induced hepatic steatosis and
lactic acidemia
Day L, Shikuma C, Gerschenson M.
Mitochondrion. 2004 Jul;4(2-3):95-109.
Abstract
 
Hepatic steatosis and HIV infection.
Ristig M, Drechsler H, Powderly WG.
AIDS Patient Care STDS. 2005 Jun;19(6):356-65.
Abstract

Metabolic Acidosis and Hepatic Steatosis in Two HIV-Infected Patients on Stavudine
(d4T) Treatment.
 Cornejo-Juarez P, Sierra-Madero J, Volkow-Fernandez P.
Arch Med Res 2003 Jan-Feb;34(1):64-9
 Abstract
 

  
           Conference Reports, Abstracts, and Posters
 
  POSTER
Hepatic Steatosis and Liver Function Abnormalities among HIV-infected Persons
N Crum-Cianflone,  C Hames, S Medina, et al
(14 CROI)
 PDF Poster      Abstract
Hepatoportal Sclerosis
       
         Journal Papers, Abstracts, and Commentaries
 
  Hepatoportal Sclerosis as a Cause of Noncirrhotic Portal Hypertension in Patients
With HIV.
Schiano TD, Kotler DP, Ferran E, Fiel MI.
AIDS. 2007 Jul 31;21(12):1591-1600
 Abstract		  
Fatty Liver Disease
       

           Journal Papers, Abstracts, and Commentaries
 
 
From nonalcoholic fatty liver to nonalcoholic steatohepatitis and cirrhosis in HIV-infected patients:
diagnosis and management.
Lemoine M, Serfaty L, Capeau J.
 Curr Opin Infect Dis. 2012 Feb;25(1):10-6..
 Abstract

Non-Alcoholic Fatty Liver Disease in HIV Infection Associated with Altered Hepatic
Fatty Acid Composition.
Arendt BM, Mohammed SS, Ma DW, et al|
Curr HIV Res. 2011 Mar 24
 Abstract

Nonalcoholic Fatty Liver Disease Among HIV-Infected Persons.
Crum-Cianflone N, Dilay A, Collins G,
J Acquir Immune Defic Syndr. 2009 Feb 16
 Abstract
 
Nonalcoholic Fatty Liver Disease in HIV-Infected Patients Referred to a Metabolic Clinic: Prevalence,
Characteristics, and Predictors.
Guaraldi G, Squillace N, Stentarelli C, et al
 Clin Infect Dis. 2008 Jun 4.
 Abstract
 
Nonalcoholic fatty liver disease: an increasingly common cause of liver disease among
HIV-infected persons?
Crum-Cianflone NF 
AIDS Read. 2007 Oct;17(10):513-8.
 Abstract
 
Nonalcoholic Fatty Liver Disease and HIV Infection.
Merriman RB. 
Curr HIV/AIDS Rep. 2006 Sep;3(3):113-7
 Abstract
 
Non-alcoholic fatty liver disease in HIV-positive patients predisposes for acute-on-chronic
liver failure: two cases.
 Kahraman A, Miller M, Gieseler RK, et al  
Eur J Gastroenterol Hepatol. 2006 Jan;18(1):101-105.
Abstract
 
Fatty liver and increased serum lactate in a woman with HIV
Lichterfeld M, Fischer HP, Spengler U, Rockstroh JK.
Dtsch Med Wochenschr 2003 Jan 17;128(3):81-4
 Abstract

Increased fat accumulation in the liver in HIV-infected patients with antiretroviral
therapy-associated lipodystrophy.
Sutinen J, Hakkinen AM, Westerbacka J,
AIDS 2002 Nov 8;16(16):2183-93
 Abstract
The fatty liver in AIDS.
Tien PC, Grunfeld C.
Semin Gastrointest Dis 2002 Jan;13(1):47-54
 Abstract

  
Hepatocellular Carcinoma
       

           Journal Papers, Abstracts, and Commentaries

 
Hepatocellular Carcinoma in HIV-Infected Patients: Check Early, Treat Hard.
Berretta M, Garlassi E, Cacopardo B,  et al
Oncologist. 2011 Aug 25.
Abstract

Influence of HIV-related immunodeficiency on the risk of hepatocellular carcinoma.
Clifford GM, Rickenbach M, Polesel J, et al
AIDS. 2008 Oct 18;22(16):2135-41.
 Abstract
 
Hepatocellular carcinoma, human immunodeficiency virus and viral hepatitis in the
HAART era.
Macdonald DC, Nelson M, Bower M, Powles T
World J Gastroenterol. 2008 Mar 21;14(11):1657-1663.
 Abstract
 
Hepatocellular carcinoma in HIV patients treated by liver transplantation.
Di Benedetto F, De Ruvo N, Berretta M, et al
 Eur J Surg Oncol. 2007 Jun 22;
 Abstract
 
 
Hepatocellular cancer in HIV-infected individuals: tomorrow's problem?
Powles T, Macdonald D, Nelson M, Stebbing J.
Expert Rev Anticancer Ther. 2006 Nov;6(11):1553-8.
 Abstract
 
Hepatocellular Carcinoma and Non-Hodgkin's Lymphoma: The Roles of HIV, Hepatitis C Infection,
and Alcohol Abuse.
McGinnis KA, Fultz SL, Skanderson M, et al  
J Clin Oncol. 2006 Nov 1;24(31):5005-9
 Abstract

Management of hepatocellular carcinoma in human immunodeficiency virus-infected patients.
Bruno R, Puoti M, Sacchi P, Filice C, et al
 J Hepatol. 2005 Dec 1;
 Abstract

The effect of HIV coinfection on the risk of cirrhosis and hepatocellular carcinoma in U.S.
veterans with hepatitis C.
Kramer JR, Giordano TP, Souchek J, et al
Am J Gastroenterol. 2005 Jan;100(1):56-63.
 Abstract
 
Cirrhosis and hepatocellular carcinoma in HIV-infected veterans with and without the hepatitis
C virus: a cohort study, 1992-2001.
Giordano TP, Kramer JR, Souchek J, et al
Arch Intern Med. 2004 Nov 22;164(21):2349-54.
 Abstract
 
Hepatocellular carcinoma in HIV-infected patients: epidemiological features, clinical
presentation and outcome.
Puoti M, Bruno R, Soriano V, et al
AIDS. 2004 Nov 19;18(17):2285-2293.
 Abstract
Liver Fibrosis
       
           Journal Papers, Abstracts, and Commentaries
 
  Evaluation of Liver Fibrosis: Concordance Analysis between Noninvasive Scores
(APRI and FIB-4) Evolution and Predictors in a Cohort of HIV-Infected Patients
without Hepatitis C and B Infection.
Mendeni M, Focà E, Gotti D, et al
Clin Infect Dis. 2011 May;52(9):1164-73.
 Abstract

FULL-TEXT PDF ARTICLE
 Prevalence and risk factors for significant liver fibrosis among HIV-monoinfected patients.
Dallapiazza M, Amorosa VK, Localio R, Kostman JR, Lo Re V 3rd.
BMC Infect Dis. 2010 May 13;10(1):116.
Paper

           Conference Reports, Abstracts, and Posters
 

 
POSTER
 Factors associated with improvement of liver fibrosis in a large cohort of HIV-infected
patients followed for 5 years
J.V. Fernández Montero, P. Labarga,  et al
(5th IAS Conference)
 PDF Poster    Abstract

Screening for liver fibrosis in HIV-mono-infected patients with increased ALT comparing FibroScan
with FIB-4
Blanco F, Barreiro P, Ryan P, et al
 (Ninth International Congress on Drug Therapy in HIV Infection)
Abstract

Surrogate markers for liver damage (i.e. how can we measure the extent of fibrosis and
disease without biopsy)
M Puoti
 (Ninth International Congress on Drug Therapy in HIV Infection)
 Abstract

  
Cholangiopathy
       
         Journal Papers, Abstracts, and Commentaries
 
  HIV/AIDS cholangiopathy: Clinical spectrum, cholangiographic features and outcome in
30 patients.
Devarbhavi H, Sebastian T, Seetharamu SM, Karanth D.
 J Gastroenterol Hepatol. 2010 Oct;25(10):1656-60
 Abstract		  
Steatohepatitis
       
         Journal Papers, Abstracts, and Commentaries
 
  From nonalcoholic fatty liver to nonalcoholic steatohepatitis and cirrhosis in HIV-infected patients:
diagnosis and management.
Lemoine M, Serfaty L, Capeau J.
 Curr Opin Infect Dis. 2012 Feb;25(1):10-6..
 Abstract		  

 

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