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HIV Infection/Disease
  Neuropathy Management

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Last Update: March 01, 2012
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General Reports
       
          Journal Papers, Abstracts, and Commentaries
 
 
Treatment Considerations in Painful HIV-Related Neuropathy.
Smith HS.
Pain Physician. 2011 Nov;14(6):E505-E524.
 Abstract

Peripheral neuropathy in HIV patients: Treatment by decompression of peripheral nerves.
Wolfort SF, Dellon AL.
 Microsurgery. 2011 Sep 14
 Abstract

FULL-TEXT ARTICLE
Treatment of HIV-Associated Nephropathies
Elewa U, Sandri AM, Rizza SA, Fervenza FC.
Nephron Clin Pract. 2011 Feb 3;118(4):c346-c354.
Paper

Diagnosis and Management of HIV-Associated Neuropathy.
Gonzalez-Duarte A, Robinson-Papp J, Simpson DM.
 Neurol Clin. 2008 Aug;26(3):821-32.
 Abstract
 
Managing HIV Peripheral Neuropathy.
Gonzalez-Duarte A, Cikurel K, Simpson DM.
 Curr HIV/AIDS Rep. 2007 Aug;4(3):114-8.
 Abstract
 
Distal sensory polyneuropathy in HIV-positive patients in the HAART era: an entity underestimated
by clinical examination.
Skopelitis EE, Kokotis PI, Kontos AN, et al  
Int J STD AIDS. 2006 Jul;17(7):467-72.
 Abstract
 
HIV neuropathy natural history cohort study: assessment measures and risk factors.
Simpson DM, Kitch D, Evans SR, et al 
Neurology. 2006 Jun 13;66(11):1679-87.
 Abstract

Clinical and subclinical neuropathy in patients with human immunodeficiency
virus receiving antiretroviral therapy.
Villelabeitia-Jaureguizar K, Rivas-Gonzalez P, et al  
Rev Neurol. 2006 May 1-15;42(9):513-20.
 Abstract

FULL-TEXT ARTICLE
Current Therapy for HIV Sensory Neuropathy
 Höke A ,Keswani  SC, McArthur JC
Current Treatment Options in Infectious Diseases 2003, 5:467-475
 Paper
Drugs
       
Anticonvulsants
 
          Journal Papers, Abstracts, and Commentaries
 
  Use of anticonvulsants for treatment of neuropathic pain.
Backonja M
Neurology 2002 Sep 10;59(5 Suppl 2):S14-7
Abstract

Capsaicin

          Journal Papers, Abstracts, and Commentaries
 
  A Randomized, Double-Blind, Controlled Study of NGX-4010, a Capsaicin 8% Dermal Patch,
for the Treatment of Painful HIV-associated Distal Sensory Polyneuropathy.
Clifford DB, Simpson DM, Brown S,   et al
J Acquir Immune Defic Syndr. 2011 Nov 7..
 Abstract

An Open-Label Pilot Study of High-Concentration Capsaicin Patch in Painful HIV Neuropathy.
 Simpson DM, Estanislao L, Brown SJ, Sampson J.
J Pain Symptom Manage. 2007 Oct 22;
 Abstract

          Conference Reports, Abstracts, and Posters

 
POSTER
A Multicenter, Randomized, Double-blind, Controlled Study of NGX-4010, a
High-concentration Capsaicin Patch, for the Treatment of Painful HIV-associated
Distal Sensory Polyneuropathy
D Clifford, D Simpson, S Brown, et al
(17th CROI)I
 PDF Poster    Abstract

Long-term intermittent treatment with high-concentration capsaicin dermal patch (CDP) for
painful HIV-associated distal sensory polyneuropathy (DSP)
Simpson D., Brown S., Chang S 
(XVI International AIDS Conference)
 Abstract

Novel High-concentration Capsaicin Patch for the Treatment of Painful HIV-a Associated
Distal Symmetrical Polyneuropathy: Results of an Open Label Trial
 D Simpson, S Brown, J Sampson, et al
 (11 CROI)
 Abstract
 
HAART
 
          Conference Reports, Abstracts, and Posters
 
  Is HAART neuro-effective in all HIV-1-positive patients?
 Arendt GR, Nolting T
 (4th IAS Conference)
 Abstract

Lamotrigine

          Journal Papers, Abstracts, and Commentaries
 
 
Double-Blind, Placebo-Controlled Trial of Lamotrigine in Combination with Other
Medications for Neuropathic Pain.
Silver M, Blum D, Grainger J, et al 
J Pain Symptom Manage. 2007 Jul 25;
 Abstract

Lamotrigine for HIV-associated painful sensory neuropathies: A placebo-controlled trial.
Simpson DM, McArthur JC, Olne   
Neurology 2003 May 13;60(9):1508-14
 Abstract
   
  A placebo-controlled trial of lamotrigine for painful HIV-associated neuropathy.
Simpson DM, Olney R, McArthur JC, et al.
Neurology 2000 Jun 13;54(11):2115-9
 Abstract

Lidocaine

          Journal Papers, Abstracts, and Commentaries
 
  A Randomized Controlled Trial of 5% Lidocaine Gel for HIV-Associated Distal Symmetric
Polyneuropathy.
Estanislao L, Carter K, McArthur J, et al
J Acquir Immune Defic Syndr. 2004 Dec 15;37(5):1584-1586
 Abstract

Marijuana(Cannabis)

          Journal Papers, Abstracts, and Commentaries
 
  Smoked Medicinal Cannabis for Neuropathic Pain in HIV: A Randomized, Crossover Clinical Trial.
Ellis RJ, Toperoff W, Vaida F, et al
Neuropsychopharmacology. 2008 Aug 6.
Abstract

          Conference Reports, Abstracts, and Posters

  PDF POSTER
 The Effect of Smoked Marijuana on Chronic Neuropathic and Experimentally Induced Pain in
HIV Neuropathy: Results of an Open-label Pilot Study
C Jay, S Shade, H Vizoso, et al.
 (11 CROI)
 PDF Poster    Abstract

Recombinant Human Nerve Growth Factor

          Journal Papers, Abstracts, and Commentaries
 
  A phase II trial of nerve growth factor for sensory neuropathy associated with HIV
infection.AIDS Clinical Trials Group Team 291.
McArthur JC, Yiannoutsos C, Simpson DM, et al.
Neurology 2000 Mar 14;54(5):1080-8
 Abstract
 
Valproic Acid

          Journal Papers, Abstracts, and Commentaries
 
  FULL-TEXT PDF ARTICLE
 Valproic acid is associated with cognitive decline in HIV-infected individuals: a clinical
observational study.
Cysique LA, Maruff P, Brew BJ.
BMC Neurol. 2006 Dec 6;6(1):42
Paper
Alternate Therapies
       
Cannabis

          Journal Papers, Abstracts, and Commentaries
 
  Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-
controlled trial
Abrams DI, Jay CA, Shade SB
Neurology 2007;68:515-521.
Abstract
 

Micronutrients

          Conference Reports, Abstracts, and Posters

  Broad-spectrum Micronutrient Supplementation in HIV-infected Patients with
Dideoxynucleoside-related Peripheral Neuropathy: A Prospective, Double Blind, Placebo-
controlled Trial
 J Kaiser, J Ondercin, G Santos, et al
 (11 CROI)
 Abstract

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Management of HIV-Associated Neuropathy