Medical Advocates
HIV Infection/Disease
  Diarrhea

 General Reports    
Pathogens
Risk Factors 
Patient Perceptions
Drug-Related Diarrhea
Management
 Quality of Life
 National Studies


 
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Last Update:  April 19, 2015
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General Reports
 

         Journal Papers, Abstracts, and Commentaries

 
Human Immunodeficiency Virus-Associated Diarrhea: Still an Issue in the Era of Antiretroviral Therapy.
Dikman AE, Schonfeld E, Srisarajivakul NC, Poles MA.
Dig Dis Sci. 2015 Mar 14
 Abstract

Unexplained diarrhoea in HIV-1 infected individuals.
Oude Munnink BB, Canuti M, Deijs M,  et al
BMC Infect Dis. 2014 Jan 13;14(1):22.
 Abstract

Intestinal spirochetosis as a cause of chronic diarrhoea in patients with HIV infection: case report and review of the literature.
Ena J, Simón-Aylón A, Pasquau F
Int J STD AIDS. 2009 Oct 20
 Abstract

FULL-TEXT ARTICLE
Etiological agents of diarrhea in patients infected by the human immunodeficiency virus-1: a review.
 Rossit AR, Gonçalves AC, Franco C, Machado RL
 Rev Inst Med Trop Sao Paulo. 2009 Mar-Apr;51(2):59-65
 Paper

Systematic Review of Strategies to Measure HIV-Related Diarrhea.
 Tinmouth J, Kandel G, Tomlinson G, et al
HIV Clin Trials. 2007 May-Jun;8(3):155-63.
 Abstract
 
Etiology of Chronic Diarrhea in Antiretroviral-Naive Patients with HIV Infection Admitted to Norodom Sihanouk Hospital, Phnom Penh, Cambodia.
 Chhin S, Harwell JI, Bell JD, et al 
Clin Infect Dis. 2006 Oct 1;43(7):925-32.
Abstract
 
Diarrhea in patients with AIDS.
 Morpeth SC, Thielman NM. 
Curr Treat Options Gastroenterol.  2006 Feb;9(1):23-37.
 Abstract
 
Chronic Diarrhea and AIDS: Insights into Studies with Non-Human Primates.
 Sestak K. 
Curr HIV Res. 2005 Jul;3(3):199-205.
 Abstract
 
Infectious diarrhea
Mottet C, El Wafa AA, Cavassini M, D'Acremont V, Delarive J.
Rev Med Suisse. 2005 Jan 19;1(3):209-10, 213-7.
 Abstract
 
Etiologies and Manifestations of Persistent Diarrhea in Adults with HIV-1 Infection:A Case-Control Study in Lima, Peru.
 Carcamo C, Hooton T, Wener MH, et al  
J Infect Dis. 2005 Jan 1;191(1):11-9.
Abstract

Evaluation of Chronic Diarrhea in Patients with Human Immunodeficiency Virus Infection.
Oldfield EC 3rd.
Rev Gastroenterol Disord 2002 Autumn;2(4):176-188
 Abstract

  
Pathogens
 

        Conference Reports, Abstracts, and Posters

 
Cryptosporidiosis in HIV- infected persons presenting with diarrhea in Jos, North central
Nigeria
Danung M.L., Badung B.P., Mu'azu M.A., et al
 (XVI International AIDS Conference)
 Abstract
 
Prevalence of Salmonella and Shigella species in HIV/AIDS patients with diarrhoea in Lagos, Nigeria
CT Oparaugo, E O Idigbe, J I Onyewuche, E B Adetiloye
 (15IAC)
Abstract
 
Spectrum of parasitic infections in AIDS associated diarrhoea
AS Chowdhary, M Joshi
 (15IAC)
Abstract
 
Spectrum of parasitic pathogens in AIDS related diarrhea in a tertiary care hospital, Belgaum, India
M B Mutnal, M B Nagamoti, C S Patil
 (15IAC)
Abstract

Pathogens associated with diarrhea among persons with and without HIV in rural Uganda
J Mermin, A Kigozi, S Malamba, et al
(14IAC)
 Abstract

Duodenal HIV-1 RNA load is increased in both HIV patients with an opportunistic intestinal pathogen or pathogen negative diarrhoea
 P McKenna, B Gazzard, P Hayes, et al.
(14IAC)
 Abstract
 
Risk Factors
 

         Journal Papers, Abstracts, and Commentaries

  FULL-TEXT ARTICLE
Failure to Eradicate Isospora belli Diarrhoea Despite Immune Reconstitution in Adults with HIV - A Case Series.
Boyles TH, Black J, Meintjes G, Mendelson M.
 PLoS One. 2012;7(8):e42844..
 Paper
Risk factors in HIV-associated diarrhoeal disease: the role of drinking water, medication and immune status.
 Eisenberg J N S, Wade T J, Charles S, et al.
 Epidemiol Infect 2002 Feb;128(1):73-81
 Abstract		  
Patient Perceptions
 

            Conference Reports, Abstracts, and Posters

  Traditional beliefs of diarrhoeal illness in children in an area of high HIV seroprevalence - implications for design and interpretation of epidemiological surveys
 S Kauchali, N Rollins, G Solarsh
 (14IAC)
 Abstract		  
Drug-Related Diarrhea
 

GW433908

          Conference Reports, Abstracts, and Posters

  GW433908 is associated with a significantly lower incidence of drug-related diarrhea and less use of antidiarrheals compared to nelfinavir in chronic HIV-infected antiretroviral therapy
naïve subjects
G Faetkenheuer, C Walworth, G Frechette,
(15IAC)
Abstract

Lopinavir

          Journal Papers, Abstracts, and Commentaries

  Differences in rates of diarrhea in patients with human immunodeficiency virus receiving lopinavir-ritonavir or nelfinavir.
 Guest JL, Ruffin C, Tschampa JM, et al 
Pharmacotherapy. 2004 Jun;24(6):727-35.
Abstract

Nelfinavir

          Journal Papers, Abstracts, and Commentaries

 
Differences in rates of diarrhea in patients with human immunodeficiency virus receiving lopinavir-ritonavir or nelfinavir.
 Guest JL, Ruffin C, Tschampa JM, et al 
Pharmacotherapy. 2004 Jun;24(6):727-35.
Abstract

The use of calcium carbonate in nelfinavir-associated diarrhoea in HIV-1-infected patients.
 Jensen-Fangel S, Justesen US, Black FT, et al 
HIV Med 2003 Jan;4(1):48-52
 Abstract

  

            Conference Reports, Abstracts, and Posters

 

Management of nelfinavir-related diarrhoea
C R Fumaz, E Negredo, J Puig, et al.
(14IAC)
Abstract

 Evaluation of pancrelipase (ultrase mt-20) for the symptomatic control of nelfinavir-
associated diarrhea
S A Tuscher, T Greenough, A Stein, et al
 (14IAC)
Abstract

  
Management
 

General Management Challenges

          Journal Papers, Abstracts, and Commentaries

 

Etiology and Pharmacologic Management of Noninfectious Diarrhea in HIV-Infected Individuals in the HAART Era.
 Macarthur RD, Dupont HL.
Clin Infect Dis. 2012 Jun 14..
 Abstract

Treatment of HIV-Associated Diarrhea with Curcumin.
 Conteas CN, Panossian AM, Tran TT, Singh HM. 
Dig Dis Sci. 2008 Dec 3
 Abstract
 
Antimotility agents for chronic diarrhoea in people with HIV/AIDS.
 Nwachukwu CE, Okebe JU. 
Cochrane Database Syst Rev. 2008 Oct 8;(4):CD005644.
 Abstract
 
Randomized Controlled Trial of Zinc Supplementation for Persistent Diarrhea in Adults With HIV-1 Infection.
 Carcamo C, Hooton T, Weiss NS, et al  
J Acquir Immune Defic Syndr. 2006 Aug 24
 Abstract

           Conference Reports, Abstracts, and Posters

 

Symptom management of diarrhea in HIV/AIDS
M J Hamilton, E Sefcik, Y Tsai, et al
 (15IAC)
Abstract

Adequate zinc intake is strongly associated with lower incidence of diarrhea in HIV+ drug users
A Campa, F Huffman, S Sales,  et al
 (15IAC)
Abstract
 
STEP-WISE INTERVENTION FOR THE MANAGEMENT OF NELFINAVIR (NFV)-ASSOCIATED DIARRHEA
A. Rachlis, M.J. Gill, J.G. Baril, et al
(2nd IAS)
Abstract

Evaluation of pancrelipase (ultrase mt-20) for the symptomatic control of nelfinavir-associated diarrhea
S A Tuscher, T Greenough, A Stein, et al
 (14IAC)
Abstract
 

Drugs

Crofelemer

          Journal Papers, Abstracts, and Commentaries
 
  Crofelemer: In HIV Associated Diarrhea and Secretory Diarrhea- A Patent Perspective.
Biswal S.
 Recent Pat Antiinfect Drug Discov. 2015 Apr 8.
 Abstract

Efficacy and Safety of Crofelemer for Noninfectious Diarrhea in HIV-Seropositive Individuals (ADVENT Trial): A Randomized, Double-Blind, Placebo-Controlled, Two-Stage Study.
 Macarthur RD, Hawkins TN, Brown SJ,  et al
HIV Clin Trials. 2013 Nov-Dec;14(6):261-73
 Abstract

FULL-TEXT ARTICLE
 Crofelemer for the treatment of chronic diarrhea in patients living with HIV/AIDS.
 Patel TS, Crutchley RD, Tucker AM,  et al
HIV AIDS (Auckl). 2013 Jul 15;5:153-62.
 Paper
 
  Crofelemer: A Review of its Use in the Management of Non-Infectious Diarrhoea in Adult Patients with HIV/AIDS on Antiretroviral Therapy.
 Frampton JE.
Drugs. 2013 Jun 27.
 Abstract
 
  Crofelemer, a novel antisecretory agent approved for the treatment of HIV-associated diarrhea.
 Yeo QM, Crutchley R, Cottreau J, Tucker A, Garey KW.
 Drugs Today (Barc). 2013 Apr;49(4):239-52
 Abstract

Mesalamine

         Journal Papers, Abstracts, and Commentaries

  Double-Blind Pilot Study of Mesalamine vs. Placebo for Treatment of Chronic Diarrhea and Nonspecific Colitis in Immunocompetent HIV Patients.
 Rodriguez-Torres M, Rodriguez-Orengo JF, Rios-Bedoya CF, et al 
Dig Dis Sci. 2006 Jan;51(1):161-7
 Abstract
Quality of Life
 

          Journal Papers, Abstracts, and Commentaries

  Association between diarrhea and quality of life in HIV-infected patients receiving highly active antiretroviral therapy.
 Tramarin A, Parise N, Campostrini S, et al. 
Qual Life Res. 2004 Feb;13(1):243-50.
 Abstract
National Studies
 
Cambodia

          Journal Papers, Abstracts, and Commentaries
 
  Etiology of Chronic Diarrhea in Antiretroviral-Naive Patients with HIV Infection Admitted to Norodom Sihanouk Hospital, Phnom Penh, Cambodia.
Chhin S, Harwell JI, Bell JD, et al
Clin Infect Dis. 2006 Oct 1;43(7):925-32.
 Abstract

India

          Conference Reports, Abstracts, and Posters

  Coccidian parasites in HIV seropositive patients with diarrhea in Pune, India
Kulkarni S., Kairon R, Kale VA, et al
 (XVI International AIDS Conference)
 Abstract
 
  Cryptosporidiosis in HIV- infected persons presenting with diarrhea in Jos, North central Nigeria
Danung M.L., Badung B.P., Mu'azu M.A., et al
 (XVI International AIDS Conference)
 Abstract
 
  Diarrhea in HIV-infected adults in Karnataka, India: evaluation of risk factors and etiology
Becker M., Cohen C., Cheang M., et al
 (XVI International AIDS Conference)
 Abstract
 
  Chronic diarrhea as presenting feature of abdominal tuberculosis in HIV/AIDS patients in a tertiary care center in India
Pazare A., Mathew Davis A., Atre Singh D.
 (XVI International AIDS Conference)
 Abstract
 
Nigeria

          Journal Papers, Abstracts, and Commentaries
 
  Diarrhea prevention in people living with HIV: an evaluation of a point-of-use water quality intervention in Lagos, Nigeria.
Barzilay EJ, Aghoghovbia TS, Blanton EM,  et al
AIDS Care. 2011 Mar;23(3):330-9.
 Abstract

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Diarrhea