Medical Advocates
HIV Infection/Disease
 
Glucose Metabolic Alterations/
Disorders
 
General Reports
Glucose Metabolism
 Glucose Intolerance
 Hyperinsulinemia
 Hyperglycemia
Insulin Resistance/Dysregulation
 Diabetes Mellitus


 
 
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Last Update: November 19, 2011
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General Reports
       

           Journal Papers, Abstracts, and Commentaries

  A Prospective Study of Body Fat Redistribution, Lipid, and Glucose Parameters in HIV-Infected Patients
Initiating Combination Antiretroviral Therapy.
 Walmsley S, Cheung AM, Fantus G, et al
 HIV Clin Trials. 2008 Sep-Oct;9(5):314-23.
 Abstract		  

Glucose Metabolism

       
           Journal Papers, Abstracts, and Commentaries
 
 
Effects of Insulin-Like Growth Factor (IGF)-I/IGF-Binding Protein-3 Treatment on
Glucose Metabolism and Fat Distribution in Human Immunodeficiency Virus-Infected
Patients with Abdominal Obesity and Insulin Resistance.
Rao MN, Mulligan K, Tai V,  et a
lJ Clin Endocrinol Metab. 2010 Jul 7
 Abstract

HIV and HIV treatment: effects on fats, glucose and lipids.
Gkrania-Klotsas E, Klotsas AE.
Br Med Bull. 2007 Nov 2
 Abstract

Disorders of glucose metabolism among HIV-infected women.
Howard AA, Floris-Moore M, Arnsten JH, et al 
Clin Infect Dis. 2005 May 15;40(10):1492-9.
Abstract
 
           Conference Reports, Abstracts, and Posters
 
 
Long-term changes in lipids and glucose/insulin levels among HIV-infected antiretroviral naïve
persons randomized to PI vs. NNRTI vs. PI + NNRTI-based antiretroviral regimens: results of
the CPCRA 061 metabolic study
Shlay J., Bartsch G., Peng G., et al 
(XVI International AIDS Conference)
 Abstract
 
Prospective Study of Glucose Metabolism in Antiretroviral Naïve HIV-Infected Patients:
Incidence of Insulin Resistance at 48 Weeks of HAART
R. PALACIOS, N. MERCHANTE, J. MACÍAS,  et al
 (45 ICAAC)
 Abstract

Disorders of Glucose Metabolism and Insulin Resistance in HIV-infected
Patients Treated with Protease Inhibitors. Considerations on Frequency and
Clinical Management, in a Prospective Randomized Study
 L Calza, RManfredi,  F Chiodo
(12 CROI)
 Abstract

  

Glucose Intolerance
       

           Journal Papers, Abstracts, and Commentaries

  Clinical lipoatrophy in HIV-1 patients on HAART is not associated with
increased abdominal girth, hyperlipidaemia or glucose intolerance.
Worm D, Kirk O, Andersen O, et al.
HIV Med 2002 Oct;3(4):239-46
 Abstract		  

Hyperglycemia
       

           Journal Papers, Abstracts, and Commentaries

  Clinical lipoatrophy in HIV-1 patients on HAART is not associated with
increased abdominal girth, hyperlipidaemia or glucose intolerance.
Worm D, Kirk O, Andersen O, et al.
HIV Med 2002 Oct;3(4):239-46
 Abstract		  

Hyperinsulinemia
       

          Journal Papers, Abstracts, and Commentaries

  Hyperinsulinemia induced by highly active antiretroviral therapy in an
adolescent with polycystic ovary syndrome who was infected with human
immunodeficiency virus.
Vigano A, Manzoni P, Riva S,  et al.  
Fertil Steril 2003 Feb;79(2):422-3
 Abstract

Hyperinsulinemic hypoglycemia associated with possible hypopituitarism in
a patient with acquired immunodeficiency syndrome.
Kim J, Mooradian AD.
 Endocr Pract 2000 Nov-Dec;6(6):453-5
 Abstract

FULL-TEXT ARTICLE
 Fasting hyperinsulinemia in human immunodeficiency virus-infected men:
relationship to body composition, gonadal function, and protease inhibitor
use.
 Hadigan C, Corcoran C, Stanley T, et al.
J Clin Endocrinol Metab 2000 Jan;85(1):35-41
Paper
 
Fasting hyperinsulinemia and increased waist-to-hip ratios in non-wasting
individuals with AIDS.
 Shikuma CM, Waslien C, McKeague J, et al.
 AIDS 1999 Jul 30;13(11):1359-65
 Abstract
 

          Conference Reports, Abstracts, and Posters

 
Effects of Metformin and Rosiglitazone on Body Composition in HIV-infected Patients with
Hyperinsulinemia and Elevated Waist/Hip Ratio: A Randomized, Placebo-controlled Trial
K Mulligan, Y Yang, S Koletar, et al
 (13 CROI)
 Abstract

Dyslipemia and Hyperinsulinemia in HIV Patients on HAART
FRANCISCO A. GOMEZ, S. P. ROMERO, et al
(41 ICAAC)
Abstract

  

Insulin Resistance/Dysregulation
       

          Journal Papers, Abstracts, and Commentaries

 
Insulin Resistance and Diabetes in HIV Infection.
Das S.
 Recent Pat Antiinfect Drug Discov. 2011 Aug 9
Abstract

Sex Hormones, Insulin Resistance, and Diabetes Mellitus among Men with or at Risk
for HIV Infection.
 Monroe AK, Dobs AS, Xu X,  et al
J Acquir Immune Defic Syndr. 2011 Jun 23
 Abstract

Lipodystrophy and insulin resistance in combination antiretroviral treated HIV-1-infected
patients: implication of resistin.
Escoté X, Miranda M, Veloso S,  et al
J Acquir Immune Defic Syndr. 2011 Feb 11.
 Abstract

A Randomized, Double-Blind, Placebo-Controlled Study of Benfluorex in HIV-Infected Patients
with Insulin Resistance or Impaired Glucose Tolerance.
Poizot-Martin, Drogoul-Vey, Di Stefano, et al
 HIV Clin Trials. 2009 Jan-Feb;10(1):33-40.
 Abstract

Proinflammatory Markers, Insulin Sensitivity, and Cardiometabolic Risk Factors in Treated HIV Infection.
 Samaras K, Gan SK, Peake PW,
Obesity (Silver Spring). 2008 Nov 13.
 Abstract
 
Antiretroviral Therapy Exposure and Insulin Resistance in the Women's Interagency HIV Study.
 Tien PC, Schneider MF, Cole SR, et al 
J Acquir Immune Defic Syndr. 2008 Oct 16
 Abstract
 
Insulin resistance and diabetes mellitus associated with antiretroviral use in HIV-infected patients:
pathogenesis, prevention, and treatment options.
Tebas P
J Acquir Immune Defic Syndr. 2008 Sep 1;49 Suppl 2:S86-92.
 Abstract
 
Insulin Resistance in HIV Infection: Drugs, Host Responses, or Restoration to Health?
Grunfeld C 
Top HIV Med. 2008 Jun-Jul;16(2):89-93.
 Abstract
 
Insulin resistance, hepatic lipid and adipose tissue distribution in HIV-infected men.
He Q, Engelson ES, Ionescu G,et al
Antivir Ther. 2008;13(3):423-8.
 Abstract
 
FULL TEXT ARTICLE
Effect of rosiglitazone and metformin on insulin resistance in patients infected with human
immunodeficiency virus receiving highly active antiretroviral therapy containing protease
inhibitor: randomized prospective controlled clinical trial.
Silic A, Janez A, Tomazic J, et al
 Croat Med J. 2007 Dec;48(6):791-9.
 Paper
 
Hepatitis C and insulin resistance: steatosis, fibrosis and non-response.
 Romero-Gomez M.
Rev Esp Enferm Dig. 2006 Aug;98(8):605-615.
 Abstract
 
Insulin Resistance in the HIV-Infected Population: The Potential Role of Mitochondrial
Dysfunction.
Shikuma CM, Day LJ, Gerschenson M.
Curr Drug Targets Infect Disord. 2005 Sep;5(3):255-62
 Abstract
 
Insulin Resistance in HIV-Infected Men and Women in the Nutrition for Healthy Living Cohort.
 Jones CY, Wilson IB, Greenberg AS
J Acquir Immune Defic Syndr. 2005 Oct 1;40(2):202-211.
Abstract
 
The Fatty liver and insulin resistance.
 Yki-Jarvinen H, Westerbacka J. 
Curr Mol Med. 2005 May;5(3):287-95
 Abstract
 
Insulin resistance, HIV infection, and anti-HIV therapies.
Taiwo BO.
AIDS Read. 2005 Apr;15(4):171-6, 179-80
 Abstract
 
Methods for quantifying insulin resistance in human immunodeficiency
virus-positive patients.
Chu JW, Abbasi F, Beatty GW
Metabolism. 2003 Jul;52(7):858-861.
 Abstract

AIDS-related Insulin Resistance and Lipodystrophy Syndrome.
Kino T, Chrousos GP.
Curr Drug Targets Immune Endocr Metabol Disord 2003 Jun;3(2):111-7
 Abstract

FULL-TEXT  ARTICLE
Insulin and Carbohydrate Dysregulation
Gelato MC
 Clinical Infectious Diseases 2003;36:S91-S95
 Paper

Bezafibrate-induced improvement in glucose uptake and endothelial function
in protease inhibitor-associated insulin resistance.
Nystrom T, Bratt G, Sjoholm A.
 J Intern Med 2002 Dec;252(6):570-4
 Abstract

FULL-TEXT ARTICLE
Impaired glucose phosphorylation and transport in skeletal muscle cause
insulin resistance in HIV-1-infected patients with lipodystrophy.
 Behrens GM, Boerner AR, Weber K, et al.
 Clin Invest 2002 Nov 1;110(9):1319-1327
 Abstract

The paradox of improved antiretroviral therapy in HIV: potential for nutritional
modulation?
 Ware LJ, Wootton SA, Morlese JM, e al.
 Proc Nutr Soc 2002 Feb;61(1):131-6
 Abstract

Insulin resistance in the HIV-lipodystrophy syndrome.
Grinspoon S.
Trends Endocrinol Metab 2001Nov 1;12(9):413-9
 Abstract

Selective aspects of the insulin resistance syndrome.
 Corry DB, Tuck ML.
 Curr Opin Nephrol Hypertens 2001 Jul;10(4):507-14
 Abstract

Major insulin resistance syndromes: clinical and physiopathological aspects
 Vigouroux C, Magre J, Desbois-Mouthon C, et al.
J Soc Biol 2001;195(3):249-57
 Abstract

  

        Conference Reports, Abstracts, and Posters

 
POSTER
 Chromium Supplementation Decreases Insulin Resistance and Trunk Fat
E Aghdassi, I Salit, S Mohammed, et al
 (15 CROI)
 PDF Poster    Abstract
 
POSTER
ART Exposure and Insulin Resistance in the Women’s Interagency HIV Study
P Tien, M Schneide, S Cole, et al
(15 CROI)
PDF Poster    Abstract
 
Improvements in Hepatic and Adipocyte Insulin Sensitivity, Dyslipidemia, and Visceral Fat
during Leptin Treatment in HIV-infected Men with Lipoatrophy and Hypoleptinemia
K Mulligan, H Khatami, J M Schwarz, et al
 (14 CROI)
 Abstract
 
Prospective Study of Glucose Metabolism in Antiretroviral Naïve HIV-Infected Patients:
Incidence of Insulin Resistance at 48 Weeks of HAART
 R. PALACIOS, N. MERCHANTE, J. MACÍAS,  et al
 (45 ICAAC)
 Abstract

Disorders of Glucose Metabolism and Insulin Resistance in HIV-infected
Patients Treated with Protease Inhibitors. Considerations on Frequency and
Clinical Management, in a Prospective  Randomized Study
 L Calza, RManfredi,  F Chiodo
(12 CROI)
 Abstract
 

  
  POSTER
 Screening for Insulin Resistance in HIV Infection
J Falutz, R Gardiner
(9 CROI)
 PDF Poster   Abstract		  
Diabetes
       

           Journal Papers, Abstracts, and Commentaries

 
Ten-year diabetes incidence in 1,046 HIV-infected patients started on a combination antiretroviral
treatment: the ANRS CO8 APROCO-COPILOTE cohort.
Capeau J, BouteloupV, Katlama C, et al
AIDS. 2011 Nov 14.
 Abstract

South Asian Consensus Guidelines for the rational management of diabetes in
human immunodeficiency virus/acquired immunodeficiency syndrome.
Kalra S, Unnikrishnan AG, Raza SA,  et al
 Indian J Endocrinol Metab. 2011 Oct;15(4):242-50
Abstract

FULL-TEXT ARTICLE
 Increased Prevalence of Albuminuria in HIV-Infected Adults with Diabetes.
Kim PS, Woods C, Dutcher L,  et al
PLoS One. 2011;6(9):e24610
 Paper

Insulin Resistance and Diabetes in HIV Infection.
 Das S.
Recent Pat Antiinfect Drug Discov. 2011 Aug 9
Abstract

HIV infection and diabetes: Experience and quality of life in patients with two chronic diseases.
Henry C, Pavese P, Blanc M,  et al
Presse Med. 2011 Aug 8.
Abstract

Sex Hormones, Insulin Resistance, and Diabetes Mellitus among Men with or at Risk
for HIV Infection.
Monroe AK, Dobs AS, Xu X,  et al
J Acquir Immune Defic Syndr. 2011 Jun 23
 Abstract

Understanding diabetes in patients with HIV/AIDS.
Kalra S, Kalra B, Agrawal N, Unnikrishnan A.
Diabetol Metab Syndr. 2011 Jan 14;3(1):2.
 Abstract

Association between Systemic Inflammation and Incident Diabetes Mellitus in
HIV-infected Patients after Initiation of Antiretroviral Therapy.
Brown TT, Tassiopoulos K, Bosch RJ, et al
Diabetes Care. 2010 Jul 27.
Abstract

FULL-TEXT PDF ARTICLE
 Elevated risks of death for diabetes mellitus and cardiovascular diseases in
Italian AIDS cases.
Serraino D, Bruzzone S, Zucchetto A, et al  
AIDS Res Ther. 2010 May 24;7(1):11.
Paper

Autoimmune Diabetes in HIV-Infected Patients on Highly Active Antiretroviral
Therapy.
Takarabe D, Rokukawa Y, Takahashi Y,  et al
 J Clin Endocrinol Metab. 2010 May 19.
Abstract

Diabetes Trends in Hospitalized HIV-Infected Persons in the United States, 1994-2004.
Kourtis AP, Bansil P, Kahn HS, et a
Curr HIV Res. 2009 Sep;7(5):481-486.
 Abstract

Are We Meeting the American Diabetes Association Goals for HIV-Infected Patients
with Diabetes Mellitus?
Adeyemi O, Vibhakar S, Max B.
Clin Infect Dis. 2009 Jul 27.
Abstract

HIV infection and the risk of diabetes mellitus.
Butt AA, McGinnis K, Rodriguez-Barradas MC, et al
A IDS. 2009 May 13.
Abstract

Risk factors for incident diabetes mellitus among HIV-infected patients receiving combination
antiretroviral therapy in Taiwan: a case-control study.
Lo YC, Chen MY, Sheng WH,  et al
HIV Med. 2009 Feb 7
 Abstract
 
Prevalence and Pathogenesis of Diabetes Mellitus in HIV-1 Infection Treated With Combined
Antiretroviral Therapy.
 Samaras K.
J Acquir Immune Defic Syndr. 2009 Feb 13
 Abstract

Diabetes Mellitus, Preexisting Coronary Heart Disease, and the Risk of Subsequent Coronary
Heart Disease Events in Patients Infected With Human Immunodeficiency Virus. The Data
Collection on Adverse Events of Anti-HIV Drugs (D:A:D Study).
Worm SW, De Wit S, Weber R, et al
 Circulation. 2009 Feb 2.
Abstract
 
Insulin resistance and diabetes mellitus associated with antiretroviral use in HIV-infected patients:
pathogenesis, prevention, and treatment options.
 Tebas P
J Acquir Immune Defic Syndr. 2008 Sep 1;49 Suppl 2:S86-92.
 Abstract
 
Incidence and risk factors for new onset diabetes mellitus in HIV infected patients:
the D:A:D study.
De Wit S, Sabin CA, Weber R, et al 
Diabetes Care. 2008 Feb 11
Abstract
 
Metabolic syndrome, cardiovascular disease and type 2 diabetes mellitus after initiation of
antiretroviral therapy in HIV infection.
 Wand H, Calmy A, Carey DL, Samaras K, et al 
AIDS. 2007 Nov 30;21(18):2445-2453.
 Abstract
 
Rosiglitazone increases small dense low-density lipoprotein concentration and decreases
high-density lipoprotein particle size in HIV-infected patients.
Hadigan C, Mazza S, Crum D, Grinspoon S.
 AIDS. 2007 Nov 30;21(18):2543-2546.
 Abstract
 
Factors associated with the incidence of type 2 diabetes mellitus in HIV-infected participants
in the Swiss HIV Cohort Study.
Ledergerber B, Furrer H, Rickenbach M, et al 
Clin Infect Dis. 2007 Jul 1;45(1):111-9.
 Abstract
 
Achieving American Diabetes Association goals in HIV-seropositive patients with
diabetes mellitus.
Bury JE, Stroup JS, Stephens JR, Baker DL.
Proc (Bayl Univ Med Cent). 2007 Apr;20(2):118-123.
 Abstract
 
A Comparison of Factors Associated With Prevalent Diabetes Mellitus Among HIV-Infected
Antiretroviral-Naive Individuals Versus Individuals in the National Health and Nutritional
Examination Survey Cohort.
Brar I, Shuter J, Thomas A, Daniels E, et al
 J Acquir Immune Defic Syndr. 2007 Jan 22
 Abstract
 
Apparent Resolution of Type 2 Diabetes Mellitus after Initiation of Potent Antiretroviral
Therapy in a Man from Africa with HIV Infection.
Koeppe J, Kosmiski L. 
Clin Infect Dis. 2006 May 15;42(10):e79-81.
Abstract

Diabetes, Insulin Resistance, and HIV.
Hadigan C. 
Curr Infect Dis Rep. 2006 Jan;8(1):69-75.
 Abstract
 
Antiretroviral therapy and the prevalence and incidence of diabetes mellitus in the multicenter
AIDS cohort study.
 Brown TT, Cole SR, Li X, et al 
Arch Intern Med. 2005 May 23;165(10):1179-84
 Abstract
 
Case-Control Study of Diabetes Mellitus in HIV-Infected Patients.
Yoon C, Gulick RM, Hoover DR, et al
J Acquir Immune Defic Syndr. 2004 Dec 1;37(4):1464-1469.
 Abstract

 
Sustaining dietary changes for preventing obesity and diabetes: lessons learned from
the successes of other epidemic control programs.
 Swinburn B.
 Asia Pac J Clin Nutr 2002;11 Suppl 3:S598-606
 Abstract
 
Syndrome of lipodystrophy, hyperlipidemia, insulin resistance, and diabetes in treated
 patients with human immunodeficiency virus infection.
 Graber AL.
 Endocr Pract 2001 Nov-Dec;7(6):430-7
 Abstract
 
Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated
lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study.
Carr A, Samaras K, Thorisdottir A, Kaufmann GR, et al. 
Lancet 1999 Jun 19;353(9170):2093-9
 Abstract
 

            Conference Reports, Abstracts, and Posters

 
Incidence and clinical manifestations for diabetes mellitus in non-obese, HIV-infected Koreans on HAART
H.K. Choi, J.Y. Choi, M.S. Kim, et al
 (5th IAS Conference)
PDF Poster      Abstract

Predicting the short-term risk of diabetes in HIV-infected patients in the D:A:D cohort:
the D:A:D study group
 Petoumenos K, Fontas E, Worm SW, et al
(Ninth International Congress on Drug Therapy in HIV Infection)
 Abstract
 
Underutilization of Recommended Interventions for Prevention of Cardiovascular Disease in
HIV-infected Patients with Established Cardiovascular Disease or Diabetes
C Sabin, R Weber, E Fontas, et al
Abstract
 
Comparison of Diabetes Mellitus Prevalence and Risk Factors among HIV-infected ART-naïve
Individuals vs Individuals in the NHANES III Cohort
IBrar, J Shute, D Wentworth, et al
(13 CROI)
Abstract
 
Diabetes Mellitus in HIV-infected Persons: The Role of CD4 Counts
A Butt, D Kelley, K McGinnis, et al 
(13 CROI)
Abstract
 
POSTER
 Duration of Indinavir and D4T Therapy Is Associated With New-Onset Type 2
Diabetes Mellitus
 H Crane, S Van Rompaey,  M Kitatata
 (11 CROI)
 PDF Poster       Abstract
 
Diabetes and Cognitive Functioning Among HIV Seropositive Patients. The Hawaii
Aging with HIV Cohort
 V Valcour, C Shikuma, B Shiramizu, et al
 (11 CROI))
 Abstract

POSTER
 Diabetes Mellitus in HIV-Infected Individuals
 JS Currier, F Boyd, H Kawabata, et al.
(9 CROI)
 PDF Poster     Abstract

POSTER
 Case-Control Study of Diabetes Mellitus in HIV-Infected Patients
C Yoon, R Gulick, D Hoover, et al.
 (9 CROI)
 PDF Poster    Abstract

POSTER
 The Effect of HAART and HCV Infection on the Development of Diabetes Mellitus
 S Mehta, R Moore, D Thomas, et al.
 (9 CROI)
 PDF Poster     Abstract

  

 

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Glucose Metabolic Alterations/Disorders