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Body Composition        
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New and Noteworthy
     
August 2010
 

July 2010
 
General Reports
 
      Journal Papers, Abstracts, and Commentaries
 
 
Pharmacogenetics of the Metabolic Disturbances and Atherosclerosis Associated with
Antiretroviral Therapy in HIV-Infected Patients.
Veloso S, Peraire J, Viladés C,  et al
Curr Pharm Des. 2010 Aug 5
 Abstract

Intermuscular Adipose Tissue and Metabolic Associations in HIV Infection.
Scherzer R, Shen W, Heymsfield SB, et al
 Obesity (Silver Spring). 2010 Jun 10.
Abstract

Metabolic changes associated with antiretroviral therapy in HIV-positive patients.
Almeida SE, Borges M, Fiegenbaum M, et al
 Rev Saude Publica. 2009 Feb 13.
 Abstract
 
Metabolic Abnormalities Associated With HIV Infection and Antiretroviral Therapy.
Fichtenbaum CJ.
Curr Infect Dis Rep. 2009 Jan;11(1):84-92
 Abstract
 
Metabolic-Inflammatory Changes, and Accelerated Atherosclerosis in HIV Patients:
Rationale for Preventative Measures.
De Lorenzo F, Collot-Teixeira S, et al
Curr Med Chem. 2008;15(28):2991
 Abstract
 
Metabolic disorders and chronic HIV and HCV infection.
Slama L, Le Camus C, Serfaty L, et al 
Diabetes Metab. 2008 Nov 27.
Abstract

Diagnosis and Management of Common Chronic Metabolic Complications in HIV-Infected Patients.
Bader MS, Kelly DV.
Postgrad Med. 2008 Nov;120(4):17-27.
 Abstract

  
Guidelines and Recommendations
 
      Journal Papers, Abstracts, and Commentaries
 
 
Serum leptin and bone metabolism in HIV patients treated with highly active antiretroviral therapy.
Madeddu G, Spanu A, Chessa F, et al 
Q J Nucl Med Mol Imaging. 2008 Jul 4.
 Abstract
 
Dietary intake and physical activity in a Canadian population sample of male patients with HIV
infection and metabolic abnormalities.
Arendt BM, Aghdassi E, Mohammed SS, et al 
Curr HIV Res. 2008 Jan;6(1):82-90
 Abstract
 
European AIDS Clinical Society (EACS) guidelines on the prevention and management of
metabolic diseases in HIV.
Lundgren JD, Battegay M, Behrens G, et al
HIV Med. 2008 Feb;9(2):72-81.
 Abstract
 
Recommendations of the Study Group for Metabolic Alterations/Secretariat for the National
AIDS Plan (GEAM/SPNS) on the management of metabolic and morphologic alterations in
patients with HIV infection.
Polo R, Jose Galindo M, Martinez E, et al
 Enferm Infecc Microbiol Clin. 2006 Feb;24(2):96-117
 Abstract
 
Strategies for Treating Morphological and Metabolic Alterations under Antiretroviral Treatment -
Appendix to the German-Austrian HIV Therapeutic Guidelines.
Mauss S, Behrens G, Walker U.  
Eur J Med Res. 2006 Feb 21;11(2):47-57.
Abstract

Management of Metabolic Complications Associated With Antiretroviral
Therapy for HIV-1 Infection :Recommendations of an International AIDS
Society-USA Panel.
Schambelan M, Benson CA, Carr A, et al.
J Acquir Immune Defic Syndr 2002 Nov 1;31(3):257-75
 Abstract

 

       Internet Document

  FULL-TEXT GUIDELINES
AACTG Metabolic Complications Guides
August 13, 2002
Guidelines		  
Body Composition/Habitus Studies
 
        Journal Papers, Abstracts, and Commentaries
 
 
Does low-dose growth hormone therapy improve the body composition of patients infected with HIV?
Nass R, Thorner MO.
 Nat Clin Pract Endocrinol Metab. 2009 Jan 20
 Abstract
 
Management of morphologic changes associated with antiretroviral use in HIV-infected patients.
Wohl DA, Brown TT.
J Acquir Immune Defic Syndr. 2008 Sep 1;49 Suppl 2:S93-S100.
 Abstract
 
Relation of Body Composition to Body Mass Index in HIV-Infected Patients With Metabolic
Abnormalities.
Joy T, Keogh HM, Hadigan C, et al
 J Acquir Immune Defic Syndr. 2007 Oct 25;
Abstract
 
Interventions for body habitus changes associated with HIV infection and its treatment.
Tebas P. 
Curr HIV/AIDS Rep. 2007 May;4(2):86-92.
 Abstract
 
Long-Term Body Composition and Metabolic Changes in Antiretroviral Naive Persons Randomized
to Protease Inhibitor-, Nonnucleoside Reverse Transcriptase Inhibitor-, or Protease Inhibitor
Plus Nonnucleoside Reverse Transcriptase Inhibitor-Based Strategy.
Shlay JC, Bartsch G, Peng G, et al
J Acquir Immune Defic Syndr. 2007 Feb 22;
 Abstract
 
Balancing disfigurement and fear of disease progression: Patient perceptions of HIV body fat
redistribution.
Reynolds NR, Neidig JL, Wu AW, et al  
AIDS Care. 2006 Oct;18(7):663-
 Abstract
 
Body shape and composition in HIV-infected women: an urban cohort.
 Karmon S, Moore R, Dobs A, Keruly J, et al 
HIV Med. 2005 Jul;6(4):245-52.
 Abstract

Body-composition measurements as predictors of glucose and insulin
abnormalities in HIV-positive men.
Meininger G, Hadigan C, Rietschel P, Grinspoon S.
Am J Clin Nutr 2002 Aug;76(2):460-465
 Abstract

Pathophysiology of body composition and metabolic abnormalities in
HIV-infection: therapeutic implications.
Hellerstein M K.
 Int J Sport Nutr Exerc Metab 2001 Dec;11 Suppl:S105-10
 Abstract

 

     Conference Reports, Abstracts, and Posters

 
Effects of Diet and Exercise and Rosiglitazone on Body Composition and Lipids, including
Oxidized LDL in HIV+ and HIV- Men and Women
D Mun, E Engelson, J Albu, et al
(15 CROI)
 Abstract
 
Dyslipidemia, Osteopenia, and Changes in Body Habitus in HIV-infected Women
 E Schoenbaum
(11 CROI)
 Abstract
 
Metabolic Disorders: General
 
         Journal Papers, Abstracts, and Commentaries
 
 
Metabolic consequences and therapeutic options in highly active antiretroviral therapy
in human immunodeficiency virus-1 infection.
 Samaras K   
J Antimicrob Chemother. 2007 Dec 10
 Abstract
 
HIV infection and high density lipoprotein metabolism.
Rose H, Hoy J, Woolley I, Tchoua U, et al 
Atherosclerosis. 2007 Dec 3
Abstract
 
The use of growth hormone to treat endocrine-metabolic disturbances in acquired immunodeficiency
syndrome (AIDS) patients
Spinola-Castro AM, Siviero-Miachon AA, da Silva MT, Guerra-Junior G.
Arq Bras Endocrinol Metabol. 2008 Jul;52(5):818-32.
 Abstract
 
Toxicogenetics of antiretroviral therapy: genetic factors that contribute to metabolic
complications.
Tarr PE, Telenti A.
Antivir Ther. 2007;12(7):999-1013.
 Abstract
 
Considering Metabolic Issues When Initiating HIV Therapy.
Wohl DA. 
Curr HIV/AIDS Rep. 2007 Aug;4(3):119-25.
 Abstract
 		  
FULL TEXT ARTICLE
 Hormonal and Metabolic Disorders of Human Immunodeficiency Virus Infection
and Substance Abuse.
Khalsa JH, Vocci F, Dobs A.
 Am J Infect Dis. 2006;2(3):125-129.
Paper
 
Long-Term Body Composition and Metabolic Changes in Antiretroviral Naive Persons
Randomized to Protease Inhibitor-, Nonnucleoside Reverse Transcriptase Inhibitor-, or
Protease Inhibitor Plus Nonnucleoside Reverse Transcriptase Inhibitor-Based Strategy.
 Shlay JC, Bartsch G, Peng G, et al
J Acquir Immune Defic Syndr. 2007 Feb 22;
 Abstract
 
Metabolic Effects of Protease Inhibitor-Sparing Antiretroviral Regimens Given as Initial
Treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095).
Shikuma CM, Yang Y, Glesby MJ, et al
J Acquir Immune Defic Syndr. 2007 Jan 22;
 Abstract
 
Metabolic Abnormalities in HIV-infected Patients: An Update.
Brown TT, Cofrancesco J.
Curr Infect Dis Rep. 2006 Nov;8(6):497-504.
 Abstract
 
Metabolic and skeletal complications of HIV infection: the price of success.
Morse CG, Kovacs JA.
JAMA. 2006 Aug 16;296(7):844-54.
 Abstract
 
Current Concepts in the Diagnosis and Management of Metabolic Complications of HIV Infection
and Its Therapy.
Wohl DA, McComsey G, Tebas P, et al 
Clin Infect Dis. 2006 Sep 1;43(5):645-53.
 Abstract
 
Highly active antiretroviral therapy-associated metabolic syndrome: pathogenesis and
cardiovascular risk
Barbaro G. 
Am J Ther. 20
Abstract
 
Highly Active Antiretroviral Therapy-Associated Metabolic Syndrome and Cardiovascular Risk.
Barbaro G, Barbarini G. 
Chemotherapy. 2006 May 2;52(4):161-165
 Abstract
 
Metabolic Syndrome Among HIV-Infected Patients: Prevalence, characteristics,
and related factors.
Jerico C, Knobel H, Montero M, et al  
Diabetes Care. 2005 Jan;28(1):132-7.
 Abstract

Role of long-term nucleoside-analogue therapy in lipodystrophy and metabolic
disorders in human immunodeficiency virus-infected patients.
Chene G, Angelini E, Cotte L, et al.
Clin Infect Dis 2002 Mar 1;34(5):649-57
 Abstract

Metabolic complications of HIV infection: translating research findings into clinical
practice.
Currier J.
AIDS Clin Care 2002 Jan;14(1):1-2, 8
 Abstract

Clinical evaluation and management of metabolic and morphologic abnormalities
associated with human immunodeficiency virus.
 Wanke CA, Falutz JM, Shevitz A, et al.
Clin Infect Dis 2002 Jan 15;34(2):248-59
 Abstract

The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose
transport in cultured adipocytes.
 Ranganathan S, Kern PA.
 J Endocrinol 2002 Jan;172(1):155-62
 Abstract

The evaluation of metabolic function and fat redistribution in clinical trials.
(No authors listed)
HIV Med 2002 Jan;3(1):65-72
 Abstract

  

        Conference Reports, Abstracts, and Posters

 
HIV infection of T cells enhances production of proteins associated with cardiovascular and
other metabolic disorders
Rasheed S, Hussain A, Yan J, Chan L
(14th IAS Conference)
Abstract
 
A Single Nucleotide Polymorphism in the Resistin Gene Is Associated with Adverse Metabolic
Changes on HAART: An Exploratory Pharmacogenetic Association Study of A5005s, the
Metabolic Sub-study of ACTG 384
K Ranade, R Parker, L Ploughman, et al
(13 CROI)
Abstract
 
Correlates of the Metabolic Syndrome among HIV Seropositive and Seronegative Men in
the Multicenter AIDS Cohort Study
 F Palella, Z Wang, H Chu, et al 
(13 CROI)
Abstract
 
POSTER
Metabolic Syndrome in HIV within a Representative US Patient Population
K Mondy, S Tong, L Kessels, et al 
(13 CROI)
PDF Poster     Abstract
 
Metabolic Syndrome and Markers of Early Atherosclerosis in a Cohort of
HIV-infected Subjects from Nutrition for Healthy Living
 A Mangili, D Jacobson, J Gerrior, et al
 (12 CROI)
 Abstract
 
Metabolic Complications of HIV Disease
(41 ICAAC)
Abstract
 
Hypoalphalipoproteinemia
 
      Journal Papers, Abstracts, and Commentaries
 
  HIV infection and high-density lipoprotein: the effect of the disease vs the effect of treatment.
Rose H, Woolley I, Hoy J, et al  
Metabolism. 2006 Jan;55(1):90-5.
 Abstract		  
Metabolic Syndrome
 
      Journal Papers, Abstracts, and Commentaries
 
 
The Hiv-1/HAART Associated Metabolic Syndrome - Novel Adipokines,
Molecular Associations And Therapeutic Implications.
Tsiodras S, Perelas A, Wanke C, Mantzoros CS.
J Infect. 2010 Jun 11
 Abstract

Metabolic Abnormalities and Coronary Heart Disease Risk in Human
Immunodeficiency Virus-Infected Adults.
Pullinger CR, Aouizerat BE, Gay Cet al 
Metab Syndr Relat Disord. 2010 Mar 17.
 Abstract

Management of the Metabolic Syndrome in Patients With Human Immunodeficiency Virus.
Feigenbaum K, Longstaff L.
Diabetes Educ. 2010 Mar 26
 Abstract

High prevalence of the metabolic syndrome in HIV-infected patients: impact of different
definitions of the metabolic syndrome.
Worm SW, Friis-Møller N, Bruyand M, et al
AIDS. 2009 Nov 11.
 Abstract

Metabolic Syndrome and Associated Cardiovascular Risk Factors in the Treatment of
Persons with HIV and Severe Mental Illness.
Vergara-Rodriguez P, Vibhakar S, Watts J.
Pharmacol Ther. 2009 Jul 29
 Abstract

Role of metabolic syndrome components in human immunodeficiency
virus-associated stroke.
Ances BM, Bhatt A, Vaida F, et al
 J Neurovirol. 2009 Jun 26:1-8
 Abstract

Metabolic syndrome associated with HIV and highly active antiretroviral therapy.
 Barbaro G, Iacobellis G.
 Curr Diab Rep. 2009 Feb;9(1):37-42
 Abstract

A WEEK IN REVIEW FEATURED REPORT
Metabolic Syndrome in Older HIV-Infected Patients: Data from the CORE50 Cohort.
 Adeyemi O, Rezai K, Bahk M, Badri S, Thomas-Gossain N.
AIDS Patient Care STDS. 2008 Dec;22(12):941-5
 Abstract
 
Presence of the metabolic syndrome (MS) is not a better predictor of cardiovascular disease (CVD)
than the sum of its components in HIV-infected individuals. Data Collection on Adverse Events of
Anti-HIV Drugs (The D:A:D study).
Worm SW, Sabin CA, Reiss P, et al  
 Diabetes Care. 2008 Dec 3
 Abstract
 
Prevalence and Predictors of Metabolic Syndrome Among HIV-Infected and HIV-Uninfected Women
in the Women's Interagency HIV Study.
Sobieszczyk ME, Hoover DR, Anastos K, et al
J Acquir Immune Defic Syndr. 2008 Jun 9.
 Abstract
 
HIV Therapy, Metabolic Syndrome, and Cardiovascular Risk.
Pao V, Lee GA, Grunfeld C. et al
Curr Atheroscler Rep. 2008 Feb;10(1):61-70
 Abstract
 
Metabolic syndrome: A major risk factor for atherosclerosis in HIV-infected patients
(SHIVA study).
Martin LD, Pasquier E, Roudaut N, et al
Presse Med. 2008 Feb 28
 Abstract
 
Metabolic syndrome, cardiovascular disease and type 2 diabetes mellitus after initiation of
antiretroviral therapy in HIV infection.
Wand H, Calmy A, Carey DL, Samaras K, et al 
AIDS. 2007 Nov 30;21(18):2445-2453.
 Abstract
 
Metabolic syndrome and cardiovascular risk in HIV-infected patients with lipodystrophy.
Falasca K, Ucciferri C, Manzoli L, et al
Int J Immunopathol Pharmacol. 2007 July-September;20(3):519-527.
Abstract
 
HIV and Metabolic Syndrome: A Comparison With the General Population. [Italy]
Bonfanti P, Giannattasio C, Ricci E, et al
J Acquir Immune Defic Syndr. 2007 May 17
 Abstract
 
Metabolic Syndrome and Subclinical Atherosclerosis in Patients Infected with HIV.
Mangili A, Jacobson DL, Gerrior J, et al
Clin Infect Dis. 2007 May 15;44(10):1368-74.
 Abstract
 
Incidence and prevalence of the metabolic syndrome in a cohort of naive HIV-infected patients:
prospective analysis at 48 weeks of highly active antiretroviral therapy.
Palacios R, Santos J, Gonzalez M, et al,
Int J STD AIDS. 2007 Mar;18(3):184-7
 Abstract
.
Metabolic Syndrome in HIV-Infected Patients from an Urban, Midwestern US Outpatient
Population.
Mondy K, Turner Overton E, Grubb J, et al
 Clin Infect Dis. 2007 Mar 1;44(5):726-34.
 Abstract
 
Prevalence of Metabolic Syndrome in HIV-Infected Patients Receiving Highly Active Antiretroviral
Therapy Using International Diabetes Foundation and Adult Treatment Panel III Criteria:
Associations with insulin resistance, disturbed body fat compartmentalization, elevated
C-reactive peptide, and hypoadiponectinemia.
Samaras K, Wand H, Law M, Emery S
Diabetes Care. 2007 Jan;30(1):113-9.
 Abstract
 
Pathogenesis of lipodystrophy and metabolic syndromes associated with HIV infection
Munoz-Sanz A, Rodriguez-Vidigal FF, Domingo P.
Med Clin (Barc). 2006 Sep 30;127(12):465-74.
 Abstract

Effects of a lifestyle modification program in HIV-infected patients with the metabolic syndrome.
Fitch KV, Anderson EJ, Hubbard JL, et al
AIDS. 2006 Sep 11;20(14):1843-50
Abstract

Toxic metabolic syndrome associated with HAART.
 Haugaard SB.
 Expert Opin Drug Metab Toxicol. 2006 Jun;2(3):429-45.
 Abstract
 
Metabolic syndrome and HIV/AIDS disorder.
 Snopkova S, Husa P.
Klin Mikrobiol Infekc Lek. 2006 Jun;12(3):109-117.
 Abstract
 
Highly active antiretroviral therapy-associated metabolic syndrome: pathogenesis and
cardiovascular risk
 Barbaro G.
 Am J Ther. 2006 May-Jun;13(3):248-60.
 Abstract
 
Highly Active Antiretroviral Therapy-Associated Metabolic Syndrome and Cardiovascular
Risk.
 Barbaro G, Barbarini G.
 Chemotherapy. 2006 May 2;52(4):161-165
 Abstract
 
 
        Conference Reports, Abstracts, and Posters
 
  Hypertension is the most common component of the metabolic syndrome in a cohort of NRTI-based HAART
treated patients – a preliminary report
Iwuala SO 
(Ninth International Congress on Drug Therapy in HIV Infection)
 Abstract
 
Metabolic syndrome among patients initiating HAART and outcome in Southern India
Saghayam S, Kumarasamy N, Sundaram M, et al  
(Ninth International Congress on Drug Therapy in HIV Infection)
 Abstract

 
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