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HIV/HCV Coinfection
 
Drugs/Alternative Therapies
 
Multiple Therapies  
Boceprevir  
Erythropoietin                       
Fluvastatin                            
Interferon
Interferon Alpha/Ribavirin
Inteleukin-2
Nitazoxanide
Peginterferon                       
Peginterferon Alpha 2a       
Peginterferon Alpha 2b   		Ribavirin
Rilpivirine
Sorafenib
Tacrolimus
Telaprevir
Antituberculosis Drugs
Milk Thistle|
 Antiretrovirals/HAART
Valacyclovir
 
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Last Update:  May 09, 2012  
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Multiple Therapies
 
      Journal Papers, Abstracts, and Commentaries
 
  FULL-TEXT ARTICLE
 Treatment of hepatitis C in HCV mono-infected and in HIV-HCV co-infected patients:
an open-labelled comparison study.
 Gonvers J, Heim M, Cavassini M, et al
Swiss Med Wkly. 2010 Jul 19;140:w13055.
Paper
Boceprevir
 
     Journal Papers, Abstracts, and Commentaries
 
  HIV-HCV co-infection facing HCV protease inhibitor licensing: implications for clinicians.
Ingiliz P, Rockstroh JK.
 Liver Int. 2012 Apr 17
 Abstract
Erythropoietin
 
      Journal Papers, Abstracts, and Commentaries
 
  Preemptive Erythropoietin Plus High Ribavirin Doses to Increase Rapid Virological
Responses in HIV Patients Treated for Chronic Hepatitis C.
 Vispo E, Labarga P, Guardiola JM, et al
AIDS Res Hum Retroviruses. 2010 Apr 8.
 Abstract
Fluvastatin
 
      Journal Papers, Abstracts, and Commentaries
 
  Fluvastatin as an adjuvant to pegylated interferon and ribavirin in HIV/hepatitis
C virus genotype 1 co-infected patients: an open-label randomized controlled study.
Milazzo L, Caramma I, Mazzali C, et al
J Antimicrob Chemother. 2010 Jan 30
 Abstract
Interferon: General Reports
 
      Journal Papers, Abstracts, and Commentaries
 
  Insulin Resistance Impairs Response to Interferon Plus Ribavirin in Patients Coinfected
With HIV and Hepatitis C Virus.
 Ryan P, Resino S, Miralles P,  et al  
J Acquir Immune Defic Syndr. 2010 Jun 23
 Abstract

    Conference Reports, Abstracts, and Posters

 
CONFERENCE PDF POSTER
 Efficacy of Pegylated Interferon + Ribavirin Treatment in HIV/HCV-co-infected Patients
Receiving Abacavir + Lamivudine or Tenofovir + either Lamivudine or Emtricitabine as
Nucleoside Analogue Backbone
 J Mira, L Lopez-Cortes, P Barreiro, et al
(15th C CROI)
 PDF Poster     Abstract

Infection Rates in HIV/HCV and HCV Patients Treated with Interferon Are Similar and not
Related to Neutropenia
(13 CROI)
 Abstract
Interferon Alpha
 
      Journal Papers, Abstracts, and Commentaries
 
 
Virus Dynamics and Immune Responses During Treatment in Patients Coinfected With
Hepatitis C and HIV.
 Talal AH, Shata MT, Markatou M
 J Acquir Immune Defic Syndr. 2004 Feb 1
 Abstract
 
FULL-TEXT ARTICLE
Fast relapse and high drop out rate of 48 weeks daily interferon monotherapy in HIV-infected
patients with chronic hepatitis C.
 Bruno R, Sacchi P, Puoti M, et al.
BMC Infect Dis 2002 Aug 28;2(1):17
Paper
Interferon Alpha/Ribavirin
 

    Journal Papers, Abstracts, and Commentaries

 
AIDS-Related Kaposi Sarcoma Can Occur during Peginterferon-{alpha} and Ribavirin Therapy for
Chronic Hepatitis C Infection.
de Lastours V, Pavie J, Delaugerre C, Molina JM.
J Int Assoc Physicians AIDS Care (Chic). 2011 Sep 20.
Abstract
Fulminant autoimmune hepatitis after successful interferon treatment in an HIV-HCV co-infected
patient.
 Coriat R, Podevin P.
 Int J STD AIDS. 2008 Mar;19(3):208-10.
Abstract
 
A WEEK IN REVIEW FEATURED REPORT
Severe weight loss in HIV / HCV-coinfected patients treated with interferon plus ribavirin:
incidence and risk factors.
 Bani-Sadr F, Lapidus N, Melchior JC, et al 
J Viral Hepat. 2008 Apr;15(4):255-60.
 Abstract
 
Rapid and early virological response to chronic Hepatitis C treatment with IFN {alpha}2b or
PEG-IFN & [alpha]2b plus ribavirin in HIV/HCV co-infected patients.
 Payan C, Pivert A, Morand P, et al
 Gut. 2007 Mar 15;
 Abstract
 
Predictive Value of Early Virologic Response in HIV/Hepatitis C Virus-Coinfected Patients
Treated With an Interferon-Based Regimen Plus Ribavirin.
 Laguno M, Larrousse M, Murillas J, et al
J Acquir Immune Defic Syndr. 2006 Nov 9;
 Abstract
 
Serious ophthalmic pathology compromising vision in HCV/HIV co-infected patients treated with
peginterferon alpha-2b and ribavirin.
 Farel C, Suzman DL, McLaughlin M, et al  
AIDS. 2004 Sep 3;18(13):1805-9.
Abstract
 
T-lymphocyte populations in hepatitis C and HIV co-infected patients treated with interferon-
alfa-2a and ribavirin.
 Neau D, Galperine T, Legrand E, et al
 HIV Med 2003 Apr;4(2):120-126
 Abstract

Pilot study of interferon alpha high-dose induction therapy in combination with ribavirin for chronic
hepatitis C in HIV-co-infected patients.
 Rockstroh JK, Mudar M, Lichterfeld M, et al.  
 AIDS 2002 Oct 18;16(15):2083-5
 Abstract

    Conference Reports, Abstracts, and Posters

 
POSTER
Interferon + Ribavirin Treatment for HCV Is Associated with Development of Hypophosphatemia in
HIV/HCV-co-Infected Patients Treated with Tenofovir-containing ART
E Funk, A Kohli, M Polis, et al
 (19 CROI)
PDF Poster     Abstract
 
POSTER
Plasma IL-6 and IL-9 Predict the Failure of Interferon-a + Ribavirin Therapy in HIV/HCV-co-infected Patients
J Berenguer, M Guzmán-Fulgencio, JL Jiménez, et al
 (19 CROI)
PDF Poster     Abstract

Long-term outcomes after peg-IFN plus pibavirin in HIV/HCV-cirrhotic patients with hypersplenism undergoing
partial splenic embolization (PSE)
 A. Moreno, R. Bárcena, C. Quereda, et al
 (XVII International AIDS Conference)
 Abstract
 
Interferon-Alfa Exposure for the Treatment of Hepatitis C Could Impair Immune Recovery in HIV
Infected Patients Under Antiretroviral Therapy
 I. MAIDA, V. SORIANO,  et al 
(45 ICAAC)
Abstract
 
Efficacy of Interferon and Ribavirin Therapy in HIV/HCV Co-infected Patients: Sustained Viral
Response Is Associated with a Rise in CD4 Lymphocyte Count
 A Urielrriero, J Lucas, et al.
(11 CROI)
 Abstract

Treatment of Chronic Hepatitis C: SHIRT (Spanish HIV Interferon Ribavirin Trial)
M. Pérez-Olmeda, V. Asensi, M. Romero,
(9RETRO)
 Abstract

  
Interleukin-2
 
    Journal Papers, Abstracts, and Commentaries
 
  Effect of IL-2 on hepatitis C virus RNA levels in patients co-infected with human
immunodeficiency virus receiving HAART.
 Tedaldi EM, Chen L, Markowitz N, et al 
J Viral Hepat. 2005 Jul;12(4):414-20.
 Abstract
   

     Conference Reports, Abstracts, and Posters
 
 
Interleukin-21-producing HCV-specific T Cells and Response to HCV Therapy in HIV/HCV-co-infected Patients
N Rallón, C Restrepo, S Fiorante, et al
 (19 CROI)
Abstract

Effects of IL-2 on Hepatitis C Virus (HCV) Replication on HIV/HCV Co-Infected Patients
M. SANCHEZ-CONDE, P. CATALAN, J. COSIN, et al 
(45 ICAAC)
Abstract

POSTER
 Pilot Study of Low Dose Daily Interleukin-2 Plus Pegylated-Interferon-alfa-2b and Ribavirin in
Patients with HCV/HIV Co-infection: ACTG A5088
MJ Glesby, R Bassett, B Alston, et al
 (11 CROI)
 PDF Poster      Abstract
Nitazoxanid
 
     Conference Reports, Abstracts, and Posters
 
 
POSTER
Augmentation of Interferon Signaling by Nitazoxanide: A Therapeutic Strategy For HIV/HCV-co-infected
Relapsers to Pegylated Interferon + Ribavirin Therapy
A  Osinusi C Wang, X Zhang, et al
(19 CROI)
PDF Poster     Abstract
Pioglitazone
 
     Conference Reports, Abstracts, and Posters
 
 
POSTER
Pilot Study of Pioglitazone Prior to HCV Re-treatment in HIV/HCV Genotype 1+Subjects with Insulin Resistance
and Prior Non-response to Pegylated Interferon + Ribavirin Therapy: ACTG 5239
K Marks, D Kitch, R Chung, et al
(19 CROI)
PDF Poster     Abstract
Ribavirin
 
     Journal Papers, Abstracts, and Commentaries
 
 
Mitochondrial Toxicity Is Associated with Virological Response in Patients with HIV
and Hepatitis C Virus Coinfection Treated with Ribavirin and Highly Active Antiretroviral Therapy.
Reiberger T, Kosi L, Maresch J,  et al
J Infect Dis. 2010 May 20.
Abstract

Early monitoring of ribavirin serum concentration is not useful to optimize hepatitis C virus
treatment in HIV-coinfected patients.
 Crespo M, Pou L, Esteban JI, et al 
Antivir Ther. 2007;12(8):1217-23.
 Abstract
 
Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse
transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus
coinfection: results of a randomized clinical study.
 Rodriguez-Torres M, Torriani FJ, Soriano V, et al
Antimicrob Agents Chemother. 2005 Oct;49(10):3997-4008.
 Abstract
 
Early Monitoring of Ribavirin Plasma Concentrations May Predict Anemia and
Early Virologic Response in HIV/Hepatitis C Virus-Coinfected Patients.
 Rendon AL, Nunez M, Romero M, et al
J Acquir Immune Defic Syndr. 2005 Aug 1;39(4):401-405.
Abstract
 

     Conference Reports, Abstracts, and Posters
 
 
POSTER
 Induction with High-dose RBV Does Not Improve HCV RNA Kinetics in HIV/HCV Co-infected Patients Starting HCV Therapy
P Labarga, P Barreiro, JM Guardiola, et al
 (18 CROI)
PDF Poster     Abstract

POSTER
 Modeling the Probability of Sustained Virologic Response to pegIFN-RBV Therapy in HCV/HIV Co-infected Patients
J Medrano, S Resino, N Rallón, et al
(18 CROI)
PDF Poster     Abstract

Ribavirin Plasma Levels at Week 4 Predicts Hepatitis C Virus Relapse in HIV/HCV-co-infected Patients Treated
for Hepatitis C
 J Morello, S Rodríguez-Nóvoa, P Barreiro, et al
 (16 CROI)
Abstract
 
Renal toxicity in HIV/Hepatitis C co-infected individuals exposed to tenofovir and/or Ribavarin
Jones R., Bower M., Mandalia S., et al
(XVI  International AIDS Conference)
Abstract

Ribavirin Plasma Concentrations throughout Hepatitis C Treatment Play a Major Role in the
Achievement of Sustained Virological Response in HIV/HCV Co-Infected Patients 
A. RENDÓN, M. NUÑEZ, M. ROMERO, et al
 (45 ICAAC)
Abstract
Rilpivirine
 
     Journal Papers, Abstracts, and Commentaries
 
  Efficacy and safety of rilpivirine in treatment-naive, HIV-1-infected patients with hepatitis B virus/
hepatitis C virus coinfection enrolled in the Phase III randomized, double-blind ECHO and THRIVE trials.
 Nelson M, Amaya G, Clumeck N, et al
 J Antimicrob Chemother. 2012 Apr 23
 Abstract
Sorafenib
 
     Journal Papers, Abstracts, and Commentaries
 
 
Sorafenib Therapy for Hepatocellular Carcinoma in an HIV-HCV Coinfected Patient:
A Case Report.
Perboni G, Costa P, Fibbia GC, et al
Oncologist. 2010 Feb 8.
 Abstract
Tacrolimus
 
     Journal Papers, Abstracts, and Commentaries
 
 
Effect of Highly Active Antiretroviral Therapy on Tacrolimus Pharmacokinetics in Hepatitis
C Virus and HIV Co-Infected Liver Transplant Recipients in the ANRS HC-08 Study.
Teicher E, Vincent I, Bonhomme-Faivre L, et al
Clin Pharmacokinet. 2007;46(11):941-52.
 Abstract
Telaprevir
 
     Journal Papers, Abstracts, and Commentaries
 
  HIV-HCV co-infection facing HCV protease inhibitor licensing: implications for clinicians.
Ingiliz P, Rockstroh JK.
 Liver Int. 2012 Apr 17
 Abstract

     Conference Reports, Abstracts, and Posters
 
 
POSTER
Early On-treatment Responses to Telapravir Do Not Differ between HIV/HCV Co-infected and HCV Mono-infected Patients
V Martel-Laferriere, K Bichoupan, A Pappas, et al
(19 CROI)
PDF Poster     Abstract

Interim Analysis of a Phase 2a Double-blind Study of TVR in Combination with pegIFN-a2a and RBV in HIV/HCV Co-infected Patients
 M Sulkowski, D Dieterich, K Sherman, et al
 (18 CROI)
 Abstract
Antituberculosis Drugs
 
     Journal Papers, Abstracts, and Commentaries
 
 
Management of Patients Coinfected With HCV and HIV: A Close Look at the Role for Direct-Acting Antivirals.
Naggie S, Sulkowski MS.
Gastroenterology. 2012 May;142(6):1324-1334.e3.
 Abstract

Changes in Hepatitis C Virus (HCV) Viral Load and Interferon-alpha Levels in HIV/HCV-Coinfected
Patients Treated With Highly Active Antiretroviral Therapy.
 Bower WA, Culver DH, Castor D, et al
 J Acquir Immune Defic Syndr. 2006 Jun 4;
 Abstract

Hepatitis B or hepatitis C co-infection in individuals infected with human immunodeficiency
virus and effect of anti-tuberculosis drugs on liver function.
 Padmapriyadarsini C, Chandrabose J, Victor L, 
J Postgrad Med. 2006 Apr-Jun;52(2):92-6.
Abstract
Valacyclovir
 
     Journal Papers, Abstracts, and Commentaries
 
  High-dose Valacyclovir HSV-2 Suppression Results in Greater Reduction in Plasma HIV-1 Levels Compared With Standard Dose Acyclovir Among HIV-1/HSV-2 Coinfected Persons: A Randomized, Crossover Trial.
Mugwanya K, Baeten JM, Mugo NR, et al
 J Infect Dis. 2011 Oct 12.
Abstract
Milk Thistle
 
     Conference Reports, Abstracts, and Posters
 
 
Pilot trial of milk thistle in HIV/hepatitis C co-infection
 G. Carter , J. Godbold  , R. MacKay
(XVII International AIDS Conference)
 Abstract

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