Medical Advocates
HCV Infection/Disease
  Extrahepatic Manifestations

 General Reports                
Anemia 
Arthritis
 Celiac Disease        
Cryoglobulinemia
 Diabetes 
Fatigue
Fibromyalgia 
 Heart Disease          
Hypercholesterolemia
 Hyperglycemia
Insulin Resistance
 Lichen Planus		 Lymphatic Disease
Mental Disorders
Neurological Disorder
 Lymphoma
 Osteosclerosis    
Polyarteritis Nodosa
Psoriasis
Renal Disease 
Rheumatologic Disease
Thrombocytopenia
 Sexual Dysfunction

 
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Last Update:  May 30, 2008
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General Reports
 

         Journal Papers, Abstracts, and Commentaries

 
Clinicopathologic correlates of hepatitis C virus in brain: a pilot study.
 Murray J, Fishman SL, Ryan E, et al 
J Neurovirol. 2008 Jan;14(1):17-27
 Abstract
 
Chronic hepatitis C with extrahepatic manifestations.
 Poantă L, Albu A.  
Rom J Intern Med. 2007;45(1):85-8.
 Abstract
 
FULL-TEXT ARTICLE
 Alterations of seminal and hormonal parameters: An extrahepatic manifestation
of HCV infection?
Durazzo M, Premoli A, Di Bisceglie C, et al
 World J Gastroenterol. 2006 May 21;12(19):3073-6
 Paper

Impact of treatment on extra hepatic manifestations in patients with chronic hepatitis C.
 Cacoub P, Ratziu V, Myers RP, et al.
Hepatol 2002 Jun;36(6):812-8
 Abstract

  
Anemia
 

         Journal Papers, Abstracts, and Commentaries

 
Anaemia in Acute HIV-1 Subtype C Infection.
Mlisana K, Auld SC, Grobler A, et al
PLoS ONE. 2008 Feb 20;3(2):e1626.
 Paper
 
Strategies for managing anemia in hepatitis C patients undergoing antiviral therapy.
 McHutchison JG, Manns MP, Brown RS Jr, et al 
Am J Gastroenterol. 2007 Apr;102(4):880-9.
 Abstract
 
Case Report: Hemolytic Anemia During Pegylated IFN-alpha2b Plus Ribavirin Treatment for Chronic
Hepatitis C: Ribavirin Is Not Always the Culprit.
 Gentile I, Viola C, Reynaud L, et al
J Interferon Cytokine Res. 2005 May;25(5):283-5
 Abstract

Treatment of hepatitis C and anemia in human immunodeficiency virus-infected patients.
Dieterich DT.
 J Infect Dis 2002 May 15;185 Suppl 2:S128-37
 Abstract

Autoimmune hemolytic anemia in chronic hepatitis C virus infection: an unusual extrahepatic
autoimmune manifestation.
 Moccia F, Tognoni E, Boccaccio P.
Ann Ital Med Int 2001 Oct-Dec;16(4):256-9
 Abstract

  
Arthritis
       
         Journal Papers, Abstracts, and Commentaries
 
 
Hepatitis C virus associated arthritis in absence of clinical, biochemical and histological
evidence of liver disease-responding to interferon therapy.
Sawada S.
 Med Sci Monit. 2005 Sep;11(9):LE10-10
 Abstract
Celiac Disease
                          
         Journal Papers, Abstracts, and Commentaries
 
  Coeliac disease in chronic hepatitis C: a French multicentre prospective study.
 Thevenot T, Denis J, Jouannaud V,et al  
Aliment Pharmacol Ther. 2007 Nov;26(9):1209-1216.
 Abstract		  
Cryoglobulinemia
       
       Journal Papers, Abstracts, and Commentaries
 
 
FULL TEXT PDF ARTICLE
 Cryoglobulinaemia in hepatitis C-positive patients in Iran.
 Owlia MB, Sami R, Akhondi M, Salimzadeh A. 
Singapore Med J. 2007 Dec;48(12):1136-9.
 Paper
 
Symptomatic and Virological Response to Antiviral Therapy in Hepatitis C Associated with
Extrahepatic Complications of Cryoglobulimia.
 Joshi S, Kuczynski M, Heathcote EJ.
Dig Dis Sci. 2007 Apr 6;
 Abstract
 
Central nervous system involvement in HCV-related mixed cryoglobulinemia.
Cappellari A, Origgi L, Spina MF, et al
Electromyogr Clin Neurophysiol. 2006 May-Jun;46(3):149-58
 Abstract
 
Polyarteritis nodosa and cryoglobulinemic glomerulonephritis related to chronic hepatitis C.
 Canada R, Chaudry S, Gaber L, et al  
Am J Med Sci. 2006 Jun;331(6):329-33.
 Abstract
 
Prevalence of cryoglobulinemia in hepatitis C virus (HCV) positive patients with and
without human immunodeficiency virus (HIV) coinfection.
 Dezzutti CS, Astemborski J, Thomas DL, et al
J Clin Virol. 2004 Nov;31(3):210-4.
 Abstract

Treatment of chronic hepatitis C infection with cryoglobulinemia.
 Della Rossa A, Tavoni A, Baldini C.
 Curr Opin Rheumatol 2002 May;14(3):231-7
 Abstract

Mixed cryoglobulinaemia and chronic hepatitis C virus infection: the rheumatic manifestations.
 Leone N, Pellicano R, Ariata Maiocco I, et al
 J Med Virol 2002 Feb;66(2):200-3
 Abstract

  
Diabetes
                          
         Journal Papers, Abstracts, and Commentaries
 
 
Hepatitis C is associated with type 2 diabetes mellitus in HIV-infected persons without
traditional risk factors.
 Jain M, Aragaki C, Fischbach L, et al
 HIV Med. 2007 Nov;8(8):491-7.
 Abstract
 
Resolution of diabetes in type 2 diabetic patient treated with IFN-alpha and ribavirin for
hepatitis C.
 Tahrani A, Bowler L, Singh P, Coates P.
Eur J Gastroenterol Hepatol. 2006 Mar;18(3):291-3.
 Abstract

Chronic hepatitis C and type II diabetes mellitus: a prospective cross-sectional study.
 Zein CO, Levy C, Basu A, Zein NN. 
Am J Gastroenterol. 2005 Jan;100(1):48-55.
Abstract

  
Fatigue
                          
         Journal Papers, Abstracts, and Commentaries
 
  Fatigue in patients with chronic hepatitis C.
 Poynard T, Cacoub P, Ratziu V, et al
J  Viral Hepat 2002 Jul;9(4):295-303
 Abstract		  
Fibromyalgia
                          
         Journal Papers, Abstracts, and Commentaries
 
  Fibromyalgia, hepatitis C infection, and the cytokine connection.
Thompson ME, Barkhuizen A. 
Curr Pain Headache Rep. 2003 Oct;7(5):342-7.
 Abstract
Heart Disease
                          
         Journal Papers, Abstracts, and Commentaries
 
  Hepatitis C associated cardiomyopathy: Potential pathogenic mechanisms and
clinical implications.
 Sanchez MJ, Bergasa NV
Med Sci Monit. 2008 May;14(5):RA55-63.
 Abstract
Hypercholesterolemia
                          
         Journal Papers, Abstracts, and Commentaries
 
  Association of hypercholesterolemia with hepatitis C virus infection in HIV-infected people.
 Polgreen P, Fultz S, Justice A, et al 
HIV Med. 2004 May;5(3):144-15
 Abstract
Hyperglycemia
                          
         Journal Papers, Abstracts, and Commentaries
 
  Hyperglycemia among persons with hepatitis C: Not the classical diabetic phenotype.
 Behrendt CE, Ruiz RB.
Diabetes Res Clin Pract. 2006 Jan;71(1):68-74.
 Abstract
Insulin Resistance
                          
         Journal Papers, Abstracts, and Commentaries
 
  A WEEK-IN-REVIEW FEATURED REPORT
FULL-TEXT ARTICLE
Insulin resistance and hepatitis C.
 Romero-Gomez M.  
World J Gastroenterol. 2006 Nov 28;12(44):7075-80
 Paper
Lichen Planus
                          
         Journal Papers, Abstracts, and Commentaries
 
  Hepatitis C virus and lichen planus.
Nagao Y, Sata M.   
J Gastroenterol Hepatol. 2004 Oct;19(10):1101-1113.
 Abstract
Lymphatic Disease
                          
         Journal Papers, Abstracts, and Commentaries
 
 
A WEEK-IN-REVIEW FEATURED REPORT
FULL TEXT ARTICLE
 Hepatitis C virus-related lymphoproliferative disorders: An overview.
Zignego AL, Giannini C, Ferri C.
 World J Gastroenterol. 2007 May 7;13(17):2467-78.
 Paper

Hepatitis C virus (HCV) I hepatitis C virus (HCV) infection and lymphoproliferative
disorders.
 Libra M, Gasparotto D, Gloghini A, Navolanic PM, et al
Front Biosci. 2005 Sep 1;10:2460-71
 Abstract
Mental Health Disorders
                          
         Journal Papers, Abstracts, and Commentaries
 
 
Could the depression of obese patients suffering from chronic hepatitis C be temporarily improved?
 Tarantino G, Basile V, Conca P, et al  
J Viral Hepat. 2008 May 27.
 Abstract
 
Therapy of interferon-induced depression in chronic hepatitis C with citalopram: A randomized,
double-blind, placebo-controlled study.
 Kraus MR, Schäfer A, Schöttker K, et al
Gut. 2007 Dec 13
Abstract
 
Association of chronic hepatitis C with major depressive disorders: irrespective of
interferon-alpha therapy.
 Carta MG, Hardoy MC, Garofalo A, et al
Clin Pract Epidemol Ment Health. 2007 Oct 23;3(1):22
Abstract
 
Is hepatitis C infection associated with increased risk of depression in persons with
methamphetamine dependence?
Vigil O, Woods SP, Moran LM, et al 
Am J Addict. 2007 Sep-Oct;16(5):418-23.
 Abstract
 
A WEEK-IN-REVIEW FEATURED REPORT
Cognitive Dysfunction in Chronic Hepatitis C: A Review.
Perry W, Hilsabeck RC, Hassanein TI. et al
Dig Dis Sci. 2007 Aug 17;
 Abstract
 
Serotonin-1A Receptor Gene HTR1A Variation Predicts Interferon-Induced Depression in
Chronic Hepatitis C.
 Kraus MR, Al-Taie O, Schafer A, et al 
Gastroenterology. 2007 Apr;132(4):1279-86.
Abstract

Schizophrenia and comorbid human immunodeficiency virus or hepatitis C virus.
Courrnos F, McKinnon K, Sullivan G.
J Clin Psychiatry. 2005;66 Suppl 6:27-33.
Abstract

Neuropsychiatric impact of hepatitis C on advanced HIV.
 Ryan EL, Morgello S, Isaacs K,et al
Neurology. 2004 Mar 23;62(6):957-6
 Abstract
Neurological Disorders
                          
         Journal Papers, Abstracts, and Commentaries
 
 
Hepatitis C virus presumably associated bilateral consecutive anterior ischemic optic
neuropathy.
 Fodor M, Nagy V, Berta A, et al  
 Eur J Ophthalmol. 2008 Mar-Apr;18(2):313-5.
 Abstract
 
Ischemic stroke accompanied by anti-PR3 antibody-related cerebral vasculitis and hepatitis C
virus infection.
 Cojocaru IM, Cojocaru M, Burcin C.  
Rom J Intern Med. 2007;45(1):47-50
 Abstract
 
Leukoencephalopathy as a rare complication of hepatitis C infection.
Buccoliero R, Gambelli S, Sicurelli F, et al
Neurol Sci. 2006 Nov;27(5):360-3.
Abstract
 
Hepatitis C virus infection and neurocognitive function.
 Soogoor M, Lynn HS, Donfield SM, et al 
Neurology. 2006 Oct 24;67(8):1482-5.
 Abstract
 
The presentation of viral hepatitis C infection without cryoglobulinemia with a peripheral
neuropathy. Five case reports
 Rafai MA, Gam I, Fadel H, et al
Rev Neurol (Paris). 2006 May;162(5):623-627.
Abstract
 
Lewis-Sumner syndrome in hepatitis C virus infection: A possible pathogenetic association
with therapeutic problems.
 Caporale CM, Capasso M, Ragno M, et al
 Muscle Nerve. 2006 Feb 1;
 Abstract
 
Pure trigeminal motor neuropathy presenting with temporo-mandibular joint dysfunction in
a patient with HIV and HCV infections.
 Anheim M, Echaniz-Laguna A, Rey D, Tranchant C.
Rev Neurol (Paris). 2006 Jan;162(1):92-4.
 Abstract

Recurrent demyelinating myelitis associated with hepatitis C viral infection.
 Grewal AK, Lopes MB, Berg CL
 J Neurol Sci. 2004 Sep 15;224(1-2):1
 Abstract

  
Lymphoma
                          
         Journal Papers, Abstracts, and Commentaries
 
 
Hepatitis C virus and lymphoma.
 Viswanatha DS, Dogan A. 
J Clin Pathol. 2007 Dec;60(12):1378-83.
Abstract
 
Hepatitis C virus and non-Hodgkin's lymphoma: findings from the Swiss HIV Cohort Study.
 Franceschi S, Polesel J, Rickenbach M, et al 
Br J Cancer. 2006 Nov 14;
 Abstract

Hepatitis C virus infection and non-Hodgkin lymphoma: results of the NCI-SEER multi-center
case-control study.
 Engels EA, Chatterjee N, Cerhan JR 
Int J Cancer. 2004 Aug 10;111(1):76-80.
 Abstract
Oxteoslerosis
                          
         Journal Papers, Abstracts, and Commentaries
 
  Hepatitis C-associated osteosclerosis (HCAO): report of a new case with involvement of the
OPG/RANKL system.
 Fiore CE, Riccobene S, Mangiafico R, et al
 Osteoporos Int. 2005 Jun 28;
Abstract		  
Psoriasis
                          
         Journal Papers, Abstracts, and Commentaries
 
 
Exacerbation of Psoriasis due to Peginterferon alpha-2b plus Ribavirin Treatment of Chronic
Active Hepatitis C.
 Kartal ED, Colak H, Ozgunes I, Usluer G.et al 
Chemotherapy. 2005 May 9;51(2-3):167-169
Abstract

Treatment of psoriasis with alefacept in patients with hepatitis C infection:
a report of two cases.
 Thaci D, Patzold S, Kaufmann R, Boehncke WH. 
Br J Dermatol. 2005 May;152(5):1048-50.
Abstract		  
Polyarteritis Nodosa
                          
         Journal Papers, Abstracts, and Commentaries
 
 
Polyarteritis nodosa and cryoglobulinemic glomerulonephritis related to chronic hepatitis C.
 Canada R, Chaudry S, Gaber L, et al  
Am J Med Sci. 2006 Jun;331(6):329-33.
 Abstract
 
Rheumatologic Disease
                          
         Journal Papers, Abstracts, and Commentaries
 
  Rheumatological manifestations of hepatitis C: incidence in a rheumatology and non-rheumatology
setting and the effect of methotrexate and interferon.
Nissen MJ, Fontanges E, Allam Y, et al  
Rheumatology (Oxford). 2005 Apr 26;
 Abstract		  
Renal Disease
 

          Journal Papers, Abstracts, and Commentaries

 
Antiviral therapy of hepatitis C in chronic kidney diseases: meta-analysis of
controlled clinical trials.
 Fabrizi F, Ganeshan SV, Lunghi G, et al  
J Viral Hepat. 2008 Apr 28
Abstract
 
Association of Hepatitis C Virus Infection With Prevalence and Development of Kidney Disease.
 Moe SM, Pampalone AJ, Ofner S, et al
 Am J Kidney Dis. 2008 Apr 25
 Abstract
 
Hepatitis C virus-related kidney disease: an overview.
 Kamar N, Izopet J, Alric L, et al 
Clin Nephrol. 2008 Mar;Volume 69(March):149-160.
 Abstract
 
Patterns in the prevalence of hepatitis C virus infection at the start of hemodialysis in Japan.
 Iwasa Y, Otsubo S, Sugi O, et al
Clin Exp Nephrol. 2008 Jan 5
Abstract
 
Chronic hepatitis C virus infection in renal transplant: treatment and outcome.
 Sharma RK, Bansal SB, Gupta A, et al 
Clin Transplant. 2006 Nov-Dec;20(6):677-83.
 Abstract
 
Relationship between Hepatitis C and Chronic Kidney Disease: Results from the Third
National Health and Nutrition Examination Survey.
 Tsui JI, Vittinghoff E, Shlipak MG, O'hare AM.
 J Am Soc Nephrol. 2006 Mar 8;
Abstract
 
Clinical presentation of chronic hepatitis C in patients with end-stage renal disease
and on hemodialysis versus those with normal renal function.
Hu KQ, Lee SM, Hu SX,  et al