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HCV Infection/Disease
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Ultrasound
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Virologic Tests
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Liver Biopsy
Diagnostic Challenges
 

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Last Update:  January 17, 2012
 
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General/Miscellaneous Reports
 

     Journal Papers, Abstracts, and Commentaries

 
Quantitation of hepatitis C virus RNA in peripheral blood mononuclear cells in HCV-monoinfection
and HIV/HCV-coinfection.
Chary A, Winters MA, Eisen R,  et al
J Med Virol. 2012 Mar;84(3):431-
Abstract

FULL-TEXT ARTICLE
"Liverscore" is predictive of both liver fibrosis and activity in chronic hepatitis C.
Arain SA, Jamal Q, Omair A.
World J Gastroenterol. 2011 Nov 7;17(41
Paper

FULL-TEXT PDF ARTICLE
HCV genotype-specific correlation with serum markers: Higher predictability for Genotype 4a.
Ahmad W, Ijaz B, Javed FT,  et al

Virol J
. 2011 Jun 10;8(1):293.
Paper

FULL-TEXT PDF ARTICLE
Applicability and precautions of use of liver injury biomarker FibroTest. A reappraisal at 7 years of age.
Poynard T, Munteanu M, Deckmyn O,

BMC Gastroenterol
. 2011 Apr 14;11(1):39
Paper

Evaluation of chronic HCV infection in transplanted livers using a modified histological
activity index.
Ziarkiewicz-Wroblewska B, Wroblewski T,  et al
Ann Transplant
. 2011 Mar 23;16(1):26-33.
Abstract

Previously unrecognized advanced liver disease unveiled by transient elastography in patients
with Haemophilia and chronic hepatitis C.
Moessner BK, Andersen ES, Weis N, et al
Haemophilia
. 2011 Mar 24
Abstract

Interpretation of real-time PCR results for HCV when viral load is below quantification limits.
Laperche S, Bouchardeau F, André-Garnier E,  et al
J Clin Microbiol
. 2011 Jan 12
Abstract

 

Contribution of HCV core antigen testing in HCV diagnosis by test from the company
Abbott Laboratorie
Trbusek J.
Epidemiol Mikrobiol Imunol
. 2010 Nov;59(4):207-8
Abstract

Distinguishing Acute from Chronic Hepatitis C Virus (HCV) Infection Based on Antibody
Reactivities to Specific HCV Structural and Non-structural Proteins.
Araujo AC, Astrakhantseva IV, Fields HA, Kamili S.
J Clin Microbiol. 2010 Nov 17
Abstract

Hepatitis C virus: Prevention, screening, and interpretation of assays.
Albeldawi M, Ruiz-Rodriguez E, Carey WD.
Cleve Clin J Med
. 2010 Sep;77(9):616-26
Abstract

Use of an anti-HCV IgG avidity assay to identify recent HCV infection.
Gaudy-Graffin C, Lesage G, Kousignian I,  et al
J Clin Microbiol
. 2010 Jul 7
.
Abstract

ELISA-based detection of C4d after liver transplantation - a helpful tool for
differential diagnosis between acute rejection and HCV-recurrence?
Schmeding M, Kienlein S, Roecken C,  et al
Transpl Immunol
. 2010 Jun 14.
Abstract

A novel duplex real-time reverse transcriptase-polymerase chain reaction assay for the
detection of hepatitis C viral RNA with armored RNA as internal control.
Meng S, Li J. 
Virol J
. 2010 Jun 7;7(1):117
Abstract

Detection of HCV RNA in saliva does not correlate with salivary flow or xerostomia in patients
with chronic hepatitis C.
de Mattos Camargo Grossmann S, Teixeira R,  et al
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jun;109(6):851-6.
Abstract

Evaluation of a rapid, point-of-care test device for the diagnosis of hepatitis C infection.
Lee SR, Yearwood GD, Guillon GB, et al
J Clin Virol
. 2010 May;48(1):15-7.
Abstract

Monitoring Hepatitis C Virus (HCV) RNA-dependent RNA polymerase
oligomerization by a FRET-based in vitro system.
Bellón-Echeverría I, López-Jiménez AJ, Clemente-Casares P, Mas A
Antiviral Res. 2010 Apr 26.
Abstract

Analytical evaluation of HCV core antigen and interest for HCV screening in haemodialysis patients.
Miedouge M, Saune K, Kamar N,  et al  
J Clin Virol
. 2010 Mar 14.
Abstract

Viral Safety of Biologicals: Evaluation of Hepatitis C Virus (HCV) Nucleic Acid
Amplification Test (NAT) Assay and Development of Concentration Method o
f HCV for Sensitive Detection by NAT.
Uchida E, Yamaguchi T.

Yakugaku Zasshi. 2010 Feb;130(2):163-
Abstract

Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system.
Jones CT, Catanese MT, Law LM, et al
Nat Biotechnol. 2010 Jan 31
Abstract

Hepatitis C virus infection diagnosis using metabonomics.
Godoy MM, Lopes EP, Silva RO,  et al|
J Viral Hepat
. 2010 Jan 13
Abstract

Program characteristics associated with testing for HIV and hepatitis C in veterans
substance use disorder clinics.
McInnes DK, Hyun JK, Trafton JA, et al
Psychiatr Serv
. 2010 Jan;61(1):90-4.
Abstract

Real-time Quantitative Assay for Routine Testing HCV RNA in Formalin-fixed,
Paraffin-embedded Liver Samples
Gruppioni E, Vasuri F, Fiorentino M, et al
Diagn Mol Pathol
. 2009 Oct 26
Abstract

Performance and clinical utility of a novel fully automated quantitative HCV-core
antigen assay.
Mederacke I, Wedemeyer H, Ciesek S, et al 
J Clin Virol
. 2009 Sep 16.
Abstract

Improvement in the aetiological diagnosis of acute hepatitis C: A diagnostic protocol
based on the anti-HCV-IgM titre and IgG Avidity Index.
Coppola N, Pisapia R, Tonziello G, Masiello et al
J Clin Virol. 2009 Sep 14.
Abstract

Improving the Diagnosis of Acute Hepatitis C Virus Infection with Expanded Viral
Load Criteria.
McGovern BH, Birch CE, Bowen MJ, et al
Clin Infect Dis
. 2009 Sep 2
Abstract

Development of a rapid one-step immunochromatographic assay for HCV core antigen detection.
Mikawa AY, Santos SA, Kenfe FR, et al  
J Virol Methods
. 2009 Jun;158(1-2):160-4.
Abstract

Assessment of liver fibrosis by transient elastography in persons with hepatitis C virus infection or HIV-hepatitis C
virus coinfection.
Kirk GD, Astemborski J, Mehta SH, et al  
Clin Infect Dis
. 2009 Apr 1;48(7):963-72.
Abstract
 

Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis.
Castera L.
J Viral Hepat. 2009 Feb 25.
Abstract
 
A new sensitive and automated chemiluminescent microparticle immunoassay for quantitative
determination of hepatitis C virus core antigen.
Morota K, Fujinami R, Kinukawa H, et al
J Virol Methods
. 2009 Jan 7
Abstract
 
Laboratory evaluation of the UniCel DxI 800 analyser (Beckman Coulter) for detecting HBV and
HCV serological markers.
Miedouge M, Legrand-Abravanel F, Lalanne C, et al
J Clin Virol
. 2008 Dec 23.
Abstract
 
Abbott RealTime HCV and Roche COBAS AmpliPrep/COBAS TaqMan HCV assay in predicting of
sustained virological response to pegylated interferon and ribavirin in chronic hepatitis C patients.
Matsuura K, Tanaka Y, Hasegawa I, et al
J Clin Microbiol. 2008 Dec 17
Abstract
 
Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C.
Boursier J, Bacq Y, Halfon P, et al
Eur J Gastroenterol Hepatol. 2009 Jan;21(1):28-38.
Abstract
 
Quantitative Tests of Liver Function Measure Hepatic Improvement after Sustained Virologic Response:
Results from the HALT-C Trial.
Everson GT, Shiffman ML, Hoefs JC, et al  
Aliment Pharmacol Ther
. 2008 Dec 1.
Abstract
 
Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests.
Calès P, Boursier J, de Lédinghen V, et al
Gastroenterol Clin Biol
2008 Nov 17
Abstract
 
Clinical performance evaluation of four automated chemiluminescence immunoassays for hepatitis C virus
antibody detection.

Kim S, Kim JH, Yoon S, Park YH, Kim HS. et al  
J Clin Microbiol.
2008 Oct 22.
Abstract
 
Validation of a hepatitis C screening tool in primary care.
McGinn T, O'Connor-Moore N, Alfandre D, et al
Arch Intern Med.
2008 Oct 13;168(18):2009-13.
Abstract
 
Diagnostic accuracy, reproducibility and robustness of fibrosis blood tests in chronic hepatitis C: A meta-analysis with
individual data.

Leroy V, Halfon P, Bacq Y, et al
Clin Biochem.
2008 Jul 11
Abstract
 
Very low hepatitis C antibody levels predict false-positive results and avoid supplemental testing.
Contreras AM, Tornero-Romo CM, Toribio JG, et al
Transfusion. 2008 Aug 1.
Abstract

Occult HCV infection revisited with ultra-sensitive real-time PCR assay.
Halfon P, Bourlière M, Ouzan D, et al  
J Clin Microbiol. 2008 Apr 30
Abstract
 

Identified cases of acute hepatitis C from computerized laboratory database: A hospital-based
epidemiological and clinical study.

Hung CH, Lu SN, Wang JH, et al
J Infect. 2008 Mar 15
Abstract
 
Integrating enhanced hepatitis C testing and counselling in research.
Winter R, Nguyen O, Higgs P,et al
Int J Drug Policy. 2008 Feb;19(1):66-70.
Abstract
 

Increasing the uptake of hepatitis C virus testing among injecting drug users in specialist
drug treatment and prison settings by using dried blood spots for diagnostic testing: a cluster
randomized controlled trial.

Hickman M, McDonald T, Judd A, et al 
J Viral Hepat.
2007 Dec 11
Abstract

Detection and quantitation of HCV RNA using real-time PCR after automated sample
processing.
Sandres-Sauné K, Abravanel F, et al
J Med Virol. 2007 Dec;79(12):1821-6
Abstract
 
Hepatitis C virus screening: performances characteristics of a commercial automated
chemiluminescent microparticle immunoassay (CMIA-ARCHITECT((R)) anti-HCV).

Petitjean Lecherbonnier J, Gouarin S, Dina J, al
Pathol Biol (Paris). 2007 Oct 22;
Paper
 
FULL TEXT PDF ARTICLE
Meta-analyses of Fibrotest diagnostic value in chronic liver disease.
Poynard T, Morra R, Halfon P, et al
BMC Gastroenterol. 2007 Oct 15;7(1):40
Paper
 
Evaluation of a new-generation line-probe assay that detects 5' untranslated and core regions to
genotype and subtype hepatitis C virus.

Nadarajah R, Khan GY, Miller SA, Brooks GF.
Am J Clin Pathol.
2007 Aug;128(2):300-4.
Abstract
 
Microarray multiplex assay for the simultaneous detection and discrimination of hepatitis B,
hepatitis C, and human immunodeficiency type-1 viruses in human blood samples.
Hsia CC, Chizhikov VE, Yang AX, et al
Biochem Biophys Res Commun. 2007 May 18;356(4):1017-23.
Abstract
 
A Prospective Analysis of the Prognostic Value of Biomarkers (FibroTest) in Patients with Chronic
Hepatitis C.
Ngo Y, Munteanu M, Messous D, et al  
Clin Chem. 2006 Aug 24;
Abstract
 
13C-methacetin breath test in hepatitis C chronic liver disease.
Oliveira AC, Reber M, Lanzoni V, et al

Arq Gastroenterol. 2006 Mar;43(1):41-44.
Abstract
 
A novel recombinant multiepitope protein as a hepatitis C diagnostic intermediate of high
sensitivity and specificity.
Dipti CA, Jain SK, Navin K.
Protein Expr Purif. 2006 Feb 6|
Abstract
 
A novel panel of blood markers to assess the degree of liver fibrosis.
Cales P, Oberti F, Michalak S, et al
Hepatology. 2005 Nov 29;42(6):1373-1381
Abstract
 
Evaluation of a total core antigen assay for the diagnosis of hepatitis C virus infection in
hemodialysis patients.
Bouzgarrou N, Fodha I, Othman SB, et al 
J Med Virol.
2005 Oct 27;77(4):502-508
Abstract
 
FULL-TEXT ARTICLE
Dried blood spots as a practical and inexpensive source for human immunodeficiency virus and
hepatitis C virus surveillance.

Toledo Jr AC, Januario JN, Rezende RM, et al 
Mem Inst Oswaldo Cruz. 2005 Jul;100(4):365-370.
Paper
 
Cost effectiveness of testing strategies for chronic hepatitis C.
Chapko MK, Sloan KL, Davison JW, et al
Am J Gastroenterol. 2005 Mar;100(3):607-15.
Abstract

Application of hepatitis serology testing algorithms to assess inappropriate
laboratory utilization.
Ozbek OA, Oktem MA, Dogan G, Abacioglu YH. 
J Eval Clin Pract.
2004 Nov;10(4):519-23.

Abstract
 

 
     Conference Reports, Abstracts, and Posters
 
 
POSTER
Avidity Assay for the Detection of Newly HCV-infected Individuals
C Mullis, A Cox, B Fisher. et al
(18 CROI)

PDF Poster     Abstract


POSTER
Evaluation of Dried Blood Spots as an Alternative Specimen for the Diagnosis of HCV Antibodies in
Resource-limited Settings

P Nandagopal, H Syed Iqbal, S Solomon,  et al
(18 CROI)
PDF Poster     Abstract

Performance and Utility of a Rapid, Point of Care Test for Hepatitis C Using Oral Fluid, Blood, Serum
and Plasma

SR Lee,KW Kardos, G Yearwood, et al
(2008 STD)
Abstract

Combination hepatitis c virus antigen and antibody immunoassay as a new tool for early
diagnosis of infection

Ansaldi F.
Bruzzone B., Frabetti M., et al;
(Conference Citations from the 12th International Symposium on Viral Hepatitis and Liver Disease)
Abstract


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Computed Tomography
 

     Journal Papers, Abstracts, and Commentaries

  Chronic hepatic disease: usefulness of serial CT examinations.
Usuki N, Miyamoto T.
J Comput Assist Tomogr 2002 May-Jun;26(3):418-21
Abstract
 

Flow Cytometry
 

     Journal Papers, Abstracts, and Commentaries

  FULL-TEXT ARTICLE
Flow cytometric detection of hepatitis C virus antigens in infected peripheral blood
leukocytes: Binding and entry.
El-Awady MK, Tabll AA, Redwan el-RM,   
World J Gastroenterol.
2005 Sep 7;11(33):5203-8. R
Paper
 

MRI
 

    Journal Papers, Abstracts, and Commentaries
 
 
Compensated hepatitis C: unenhanced MR imaging correlated with pathologic grading and staging.
Mitchell DG, Navarro VJ, Herrine SK, et al
Abdom Imaging.
2007 Mar 27;
Abstract

Cirrhosis or Chronic Hepatitis: Evaluation of Small (</=2-cm) Early-Enhancing Hepatic
Lesions with Serial Contrast-enhanced Dynamic MR Imaging.

Shimizu A, Ito K, Koike S, et al
Radiology
2003 Feb;226(2):550-5
Abstract

 

Ultrasound
       

    Journal Papers, Abstracts, and Commentaries

 
FULL-TEXT ARTICLE
Role of microbubble ultrasound contrast agents in the non-invasive assessment of chronic
hepatitis C-related liver disease.
Grier S, Lim AK, Patel N, et al 
World J Gastroenterol. 2006 Jun 14;12(22):3461-5.
Paper
 
FULL-TEXT PDF ARTICLE
The accuracy of the report of hepatic steatosis on ultrasonography in patients infected with
hepatitis C in a clinical setting: A retrospective observational study.

Hepburn MJ, Vos JA, Fillman EP, Lawitz EJ.
BMC Gastroenterol. 2005 Apr 13;5(
1):14
Paper
 
Can ultrasonographic findings of perihepatic lymphadenopathy promote investigations
to detect possible presence of virus C infection in non-symptomatic subjects?
Neri S, Ierna D, Mauceri B, et al

Hepatol Res.
2003 Oct;27(2):124-128.
Abstract

Ultrasound detection of abdominal lymph nodes in chronic liver diseases.A
retrospective analysis.

Soresi M, Bonfissuto G, Magliarisi C, et al.
Clin Radiol
2003 May;58(5):372-7

Abstract

 

Antibody/Antigen
      

    Journal Papers, Abstracts, and Commentaries

 
HCV core antigen testing in HIV- and HBV-coinfected patients, and in HCV-infected patients on hemodialysis.
Mederacke I, Potthoff A, Meyer-Olson D, et al
J Clin Virol. 2011 Dec 14
Abstract

Comparison of a newly developed automated and quantitative hepatitis C virus (HCV) core antigen test with the HCV RNA assay for the clinical usefulness of confirming anti-HCV results.
Kesli R, Polat H, Terzi Y, et al

J Clin Microbiol
. 2011 Sep 21
Abstract

Comparison of a newly developed automated and quantitative hepatitis C virus (HCV) core antigen test with the
HCV RNA assay for the clinical usefulness of confirming anti-HCV results.
Kesli R, Polat H, Terzi Y, et al
J Clin Microbiol
. 2011 Sep 21.
Abstract

Utility of a commercial quantitative hepatitis C virus core antigen assay in a diagnostic laboratory setting.
Ergünay K, Sener B, Alp A,  et al
Diagn Microbiol Infect Dis
. 2011 Aug;70(4):486-91.
Abstract

Performance characteristics of a combined hepatitis C virus core antigen and anti-hepatitis C virus
antibody test in different patient groups.
Yang JF, Lin YY, Hsieh MH,  et al
Kaohsiung J Med Sci
. 2011 Jul;27(7):258-
Abstract


The assessment of serum HCV RNA 12 weeks after the end of treatment using TaqMan PCR
is less relevant than after 24 weeks for predicting SVR.
Kanda T, Imazeki F, Wu S, Nakamoto S, Yokosuka O.
Hepatology. 2011 Jul 2.
Abstract

Abbott RealTime PCR assay is useful for evaluating virological response to antiviral treatment
for chronic hepatitis C.
Ikezaki H, Furusyo N, Ihara T, et al

J Infect Chemother
. 2011 Apr 29
Abstract

Distinguishing Acute from Chronic Hepatitis C Virus (HCV) Infection Based on Antibody
Reactivities to Specific HCV Structural and Non-structural Proteins.
Araujo AC, Astrakhantseva IV, Fields HA, Kamili S.
J Clin Microbiol. 2010 Nov 17
Abstract

FULL-TEXT PDF ARTICLE
Excellent superiority and specificity of COBAS TaqMan HCV assay in an |
early viral kinetic change during pegylated interferon alpha-2b plus ribavirin
treatment.

Ogawa E, Furusyo N, Toyoda K,  et al
BMC Gastroenterol
. 2010 Apr 16;10(1):38
Paper

Evaluation of a rapid, point-of-care test device for the diagnosis of hepatitis C infection.
Lee SR, Yearwood GD, Guillon GB, et al
J Clin Virol
. 2010 Mar 31.
Abstract

High diagnostic accuracy of antigen microarray for sensitive detection of hepatitis C virus
infection
.
Kwon JA, Lee H, Lee KN, et al
Clin Chem. 2008 Feb;54(2):424-8.
Abstract

Sensitivity of a rapid immuno-chromatographic test for Hepatitis C antibodies detection.
Desbois D, Vaghefi P, Savary J, et al 
J Clin Virol. 2
007 Dec 7
Abstract
 

Evaluation of the available anti-HCV antibody Detection Tests and RT-PCR assay in the
Diagnosis of Hepatitis C Virus Infection.
Tashkandy MA, Khodari YA, Ibrahim AM,et al
Saudi J Kidney Dis Transpl.
2007 Oct-Dec;18(4):523-31.
Abstract
 
Early detection of hepatitis C virus infection by use of a new combined antigen-antibody
detection assay: potential use for high-risk individuals.

Schnuriger A, Dominguez S, Valantin MA, et al 
J Clin Microbiol.
2006 Apr;44(4):1561-3.
Abstract
 
FULL TEXT ARTICLE
A focus reduction neutralization assay for hepatitis C virus neutralizing antibodies.
Fournier C, Duverlie G, Francois C, et al 
Virol J.
2007 Mar 30;4:35.
Paper
 
FULL-TEXT ARTICLE
Hepatitis C Virus Serologic and Virologic Tests and Clinical Diagnosis of HCV-Related Liver
Disease.
Chevaliez S, Pawlotsky JM. 
Int J Med Sci. 2006;3(2):35-40.
Paper
 
Is it possible to diagnose acute hepatitis C virus (HCV) infection by a rising anti-HCV
titre rather than by seroconversion?
Lu SN, Tung HD, Chen TM, et al  
J Viral Hepat. 2004 Nov;11(6):563-70.
Abstract
 
Evaluation of a modified commercial assay in detecting antibody to hepatitis C
virus in oral fluids and dried blood spots.
Judd A, Parry J, Hickman M, et al
J Med Virol. 2003 Sep;71(1):49-55.
Abstract

FULL-TEXT ARTICLE
Guidelines for Laboratory Testing and Result Reporting of Antibody to Hepatitis
C Virus
MMWR February 7, 2003 / Vol. 52 / No. RR--3
Paper

Comparison of second- and third-generation enzyme immunoassays for detecting
antibodies to hepatitis C virus.
Abdel-Hamid M, El-Daly M, El-Kafrawy S, et al.
J Clin Microbiol 2002 May;40(5):1656-9
Abstract
 

 
    Conference Reports, Abstracts, and Posters
 
  Performance and Utility of a Rapid, Point of Care Test for Hepatitis C Using Oral Fluid, Blood,
Serum and Plasma
SR Lee, K Kardos, G Yearwood, et al
(2008 National STD Prevention Conference
)
Abstract

Virologic Tests
         

     Journal Papers, Abstracts, and Commentaries

 
The use of real-time PCR to detect hepatitis C virus RNA in dried blood spots from
Brazilian patients infected chronically.
Santos C, Reis A, Dos Santos CV,  et al
J Virol Methods. 2011 Jun 24.
Abstract

Hepatitis C virus RNA assays: current and emerging technologies and their clinical applications.
Al Olaby RR, Azzazy HM.

Expert Rev Mol Diagn
. 2011 Jan;11(1):53-64.
Abstract

FULL-TEXT PDF ARTICLE
Quantitative analysis of interferon alpha receptor subunit 1 and suppressor of cytokine
signaling 1 gene transcription in blood cells of patients with chronic hepatitis C.

Sedeno-Monge V, Santos-Lopez G, Rocha-Gracia RC,  et al 
Virol J
. 2010 Sep 18;7(1):243.
Paper

Performance evaluation of the Abbott RealTime HCV Genotype II for hepatitis C
virus genotyping.
Sohn YH, Ko SY, Kim MH, Oh HB.
Clin Chem Lab Med
. 2010 Feb 4
Abstract

Viral RNA Testing in Hepatitis C Antibody-Positive Veterans.
Rongey CA, Kanwal F, Hoang T, Gifford AL, Asch SM.
Am J Prev Med. 2009 Jan 20
Abstract
 

Differences between two real-time PCR based assays (RealTime HCV, COBAS AmpliPrep/
COBAS TaqMan) and one signal amplification assay (VERSANT HCV RNA 3.0) for HCV RNA

detection and quantification.
Vermehren J, Kau A, Gärtner BC, et al
J Clin Microbiol.
2008 Sep 17.
Abstract
 
End-point limiting-dilution real-time PCR assay for evaluation of hepatitis C virus quasispecies in serum:
Performance under optimal and suboptimal conditions.
Ramachandran S, Xia GL, Ganova-Raeva LM, Nainan OV, Khudyakov Y.
J Virol Methods. 2008 Jun 19.
Abstract
 
Quantitation of hepatitis C virus using an in-house real-time reverse transcriptase polymerase chain
 reaction in plasma samples.
Daniel HD, Chandy GM, Abraham P
Diagn Microbiol Infect Dis. 2008 May 15.
Abstract
 
Evaluation of the Versant HCV genotype assay A (LiPA) 2.0.
Verbeeck J, Stanley MJ, Shieh J, et al
J Clin Microbiol.
2008 Apr 9
Abstract
 
Predicting sustained virological response in chronic hepatitis C patients treated with
pegylated interferon and ribavirin using a novel highly sensitive Real-time detection
PCR assay

Matsuura K, Tanaka Y, Takagi K, et al 
Rinsho Byori.
2007 Nov;55(11):983-8
Abstract
 
Clinical evaluation of the COBAS Ampliprep/COBAS TaqMan for HCV RNA
quantitation in comparison with the branched-DNA assay.

Pittaluga F, Allice T, Abate ML
J Med Virol. 2007 Dec 20;80(2):254-260
Abstract
 
Qualitative application of cobas amplicor HCV test version 2.0 assays in patients with chronic
hepatitis C virus infection and comparison of clinical performance with version 1.0.

Hsieh MY, Lee LP, Hou NJ, et al 
Kaohsiung J Med Sci.
2007 Jul;23(7):332-8
Abstract
 
Comparison of the Abbott 7000 and the Bayer 340 Systems for the Measurement of HCV
Viral Load.
Highbarger HC, Hu Z, Kottilil S, et al 
J Clin Microbiol.
2007 Jun 27;
Abstract
 
Prediction of the efficacy of antiviral therapy for hepatitis C virus infection by an
ultrasensitive RT-PCR assay.

Kinai E, Hanabusa H, Kato S.
J Med Virol. 2007 Jun 27;79(8):1113-1119
Abstract
 
Impact of Hepatitis C Virus (HCV) genotypes on quantification of HCV RNA in serum by Cobas
AmpliPrep/Cobas TaqMAN HCV Test, Abbott ART HCV RealTime assay and VERSANT HCV
RNA Assay.

Tuaillon E, Mondain AM, Ottomani L, et al
J Clin Microbiol. 2007 Jun 20;
Abstract
 
Overestimation and underestimation of hepatitis C virus RNA levels in a widely used real-time
polymerase chain reaction-based method.

Chevaliez S, Bouvier-Alias M, Brillet R, Pawlotsky JM.  |
Hepatology. 2
007 May 24
Abstract
 
Evaluation of the Ortho-Clinical Diagnostics Vitros ECi Anti-HCV test: comparison with three
other methods.

Watterson JM, Stallcup P, Escamilla D, et al
J Clin Lab Anal.
2007 May 16;21(3):162-166
Abstract
 
Prognostic Significance of Hepatitis C Virus RNA Detection by Transcription-Mediated
Amplification with Negative Polymerase Chain Reaction During Therapy with Peginterferon alpha
and Ribavirin.
Kadam JS, Gonzalez SA, Ahmed F
Dig Dis Sci. 2007 Apr 4;
Abstract
 
Fully automated quantification of hepatitis C virus (HCV) RNA in human plasma and human serum
by the COBAS AmpliPrep/COBAS TaqMan System.

Sizmann D, Boeck C, Boelter J, et al 
J Clin Virol.
2007 Mar 5;
Abstract
 
Evaluation of the Abbott RealTime HCV assay for quantitative detection of hepatitis C virus RNA.
Michelin BD, Muller Z, Stelzl E, et al
J Clin Virol. 2006 Dec 19
Abstract
 
Comparison of Conventional PCR with Real-Time PCR and Branched DNA-Based Assays
for Hepatitis C Virus RNA Quantification and Clinical Significance for Genotypes 1 to 5.
Sarrazin C, Gartner BC, Sizmann D, et al 
Clin Microbiol. 2006 Mar;44(3):729-37.
Abstract
 
Evaluation of the invader assay for genotyping hepatitis C virus.
Germer JJ, Majewski DW, Yung B, et al
J Clin Microbiol. 2006 Feb;44(2):318-23.
Abstract
 
Assessment of early virological response to antiviral therapy by comparing four assays for HCV
RNA quantitation using the international unit standard: Implications for clinical management of
patients with chronic hepatitis C virus infection.
Halfon P, Penaranda G, Bourliere M,
Med Virol. 2006 Feb;78(2):208-15.
Abstract
 
Use of a Commercially Available Line Probe Assay for Genotyping of Hepatitis C Virus 5a Strains.
Verbeeck J, Maes P, Wollants E, et al
J Clin Microbiol. 2005 Dec;43(12):6117-6119.
Abstract
 
A real-time Taqman method for hepatitis C virus genotyping.
Rolfe KJ, Alexander GJ, Wreghitt TG
J Clin Virol
. 2005 May 11
Abstract
 

Evaluation of the COBAS Hepatitis C Virus (HCV) TaqMan Analyte-Specific Reagent Assay
and Comparison to the COBAS Amplicor HCV Monitor V2.0 and Versant HCV bDNA 3.0
Assays.
Konnick EQ, Williams SM, Ashwood ER, Hillyard DR. 
Clin Microbiol. 2005 May;43(5):2133-40.
Abstract
 

HCV genotyping by combination of Cobas Amplicor HCV 2.0 test and Versant HCV
Genotype Assay

Nemcova J, Nemecek V. 
Epidemiol Mikrobiol Imunol. 2005 Feb;54(1):34-8
Abstract
 
TRUGENE sequencing versus INNO-LiPA for sub-genotyping of HCV genotype-4.
Zekri AR, Alam El-Din HM, Bahnassy AA, et al 
J Med Virol. 2005 Mar;75(3):412-20.
Abstract
 
New combination test for hepatitis C virus genotype and viral load determination using
Amplicor GT HCV MONITOR test v2.0.
Mukaide M, Tanaka Y, Kakuda H, et al
World J Gastroenterol. 2005 Jan 28;11(4):469-75
Abstract
 
Evaluation of the COBAS TaqMan HCV Test with Automated Sample Processing
Using the MagNA Pure LC Instrument.
Germer JJ, Harmsen WS, Mandrekar JN, et al
J Clin Microbiol.
2005 Jan;43(1):293-8.
Abstract
 
Role of polymerase chain reaction and liver biopsy in the evaluation of patients with
asymptomatic transaminitis: Implications in diagnostic approach. 
Madan K, Batra Y, Panda SK, et al
J Gastroenterol Hepatol.
2004 Nov;19(11):1291-9
Abstract
 
Inter-laboratory comparison of qualitative and quantitative detection of hepatitis C
(HCV) virus RNA in diagnostic virology: a multicentre study (MS) in Italy.

Mancini C, Pisani G, Azzi A, et al 
J Clin Virol. 2004 Aug;30(4):313-9.

Abstract
 
Expertise of French Laboratories in Detection, Genotyping, and Quantification of
Hepatitis C Virus RNA in Serum.
Lefrere JJ, Roudot-Thoraval F,et al 
J Clin Microbiol. 2004 May;42(5):2027-2030.

Abstract
 
Evaluation of a new NASBA assay for the qualitative detection of hepatitis C virus
based on the NucliSens Basic Kit reagents.
Guichon A, Chiparelli H, Marti;nez A, et al. 
J Clin Virol.
2004 Feb;29(2):84-91
Abstract
 
Predictive value of early HCV RNA quantitation for sustained response in
nonresponders receiving daily interferon and ribavirin therapy.
Trimoulet P, De Ledinghen V, Foucher J, et al 
J Med Virol. 2004 Jan;72(1):46-51
Abstract
 
Direct comparison of hepatitis C virus genotypes tested by INNO-LiPA HCV II and
TRUGENE HCV genotyping methods.
Zheng X, Pang M, Chan A, et al

Clin Virol. 2003 Oct;28(2):214-6.
Abstract
 
Successful HCV genotyping of previously failed and low viral load specimens using an
HCV RNA qualitative assay based on transcription-mediated amplification in conjunction
with the line probe assay.
Comanor L, Elkin C, Leung K, et al  
J Clin Virol. 2003 Sep;28(1):14-26.
Abstract
 
Comparison of different HCV viral load and genotyping assays.
Anderson JC, Simonetti J, Fisher DG, et al 

J Clin Virol. 2
003 Sep;28(1):27-37
Abstract
 
Direct comparison of hepatitis C virus genotypes tested by INNO-LiPA HCV II and
TRUGENE HCV genotyping methods.
Zheng X, Pang M, Chan A, et al.

J Clin Virol
. 2003 Oct;28(2):214-6.
Abstract
 
Evaluation of the MagNA Pure LC Instrument for Extraction of Hepatitis C Virus RNA
for the COBAS AMPLICOR Hepatitis C Virus Test, Version 2.0.
Germer JJ, Lins MM, Jensen ME, et al  

Clin Microbiol.
2003 Aug;41(8):
Abstract

Genotyping of hepatitis C virus-comparison of three assays.
Haushofer AC, Berg J, Hauer R, et al
J Clin Virol. 2003 Aug;27(3):276-85.
Abstract
 

 

Quantitative assay of hepatitis C virus RNA using an automated extraction system for
specific capture with probes and paramagnetic particle separation
.
Miyachi H, Masukawa A, Asai S, et al
Clin Microbiol
2003 Feb;41(2):572-5
Abstract

Hepatitis C viral load does not predict disease outcome: going beyond numbers.
de Araujo ES, Cavalheiro Nde P, et al.
Rev Inst Med Trop Sao Paulo 2002 Mar-Apr;44(2):71-8
Abstract

Significant closure of the human immunodeficiency virus type 1 and hepatitis C virus
preseroconversion detection windows with a transcription-mediated-amplification-driven
assay.
Kolk DP, Dockter J, Linnen J, et al.
J Clin Microbiol 2002 May;40(5):1761-6
Abstract

Highly Sensitive Multiplex Assay for Detection of Human Immunodeficiency Virus Type 1
and Hepatitis C Virus RNA

Giachetti C,  Linnen JM,  Kolk DP, et al
J. Clin. Microbiol. 2002 40: 2408-2419.

Abstract

Sensitivity of the Procleix HIV-1/HCV Assay for Detection of Human Immunodeficiency
Virus Type 1 and Hepatitis C Virus RNA in a High-Risk Population.
Jackson JB, Smith K, Knott C, et al.
J Clin Microbiol 2002 Jul;40(7):2387-91
Abstract

FULL-TEXT ARTICLE
Prospective Multicenter Clinical Evaluation of AMPLICOR and COBAS AMPLICOR
Hepatitis C Virus Tests

Nolte FS, Fried MW, Shiffman ML, et al.
J. Clin. Microbiol. 2001 39: 4005-4012.
Paper

 

    Conference Reports, Abstracts, and Posters

  CONFERENCE PRESENTATION
Use and Interpretation of Virologic Tests 
Pawlotsky, JM
[NIH Consensus Development Conference on Management of Hepatitis C: 2002]
Report
 

Serum Titer
       

   Journal Papers, Abstracts, and Commentaries
 
 
FULL-TEXT ARTICLE
FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
Patel K, Friedrich-Rust M, Lurie Y, Grigorescu M, et al

World J Gastroenterol
. 2011 Nov 7;17(41):4581-9.
Paper

Serum levels of hepatitis C virus core antigen as a marker of infection and response to
therapy.
Soffredini R, Rumi MG, Parravicini ML, et al
Am J Gastroenterol. 2004 Sep;99(9):1738-43.
Abstract

FULL-TEXT ARTICLE
Assessment of correlation between serum titers of hepatitis c virus and severity of liver
disease.
Anand BS, Velez M.
World J Gastroenterol
. 2004 Aug 15;10(16):2409-11.
Paper


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